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- Xiangdong Gongye
Xiangdong Gongye
Doctoral Student
Department of Chemistry & Molecular Biology-
MTARC1 p.A165 ablation reduces hepatocellular carcinoma aggressiveness in vitro and in
vivo
Lohitesh Kovooru, Jingjing Zhang, Francesco Giuseppe Monni, Tanmoy Dutta, Xiangdong Gongye, Bernice Asiedu, Patrizia Infelise, Emelie Barreby, Oveis Jamialahmadi, Margit Mahlapuu, Rosellina Mancina, Stefano Romeo
Clinical and Molecular Hepatology - 2026 -
Targeting STE20-type kinase MST3 improves metabolic dysfunction-associated steatohepatitis without affecting hepatocellular carcinoma development in
mice
Jingjing Zhang, Xiangdong Gongye, Lohitesh Kovooru, Emma Andersson, Bernice Asiedu, Manoj Amrutkar, Nadia Gul, Caitlyn Myers, Sheri Booten, Dan Lind, Ying Xia, Antonio Molinaro, Anetta Härtlova, Per Lindahl, Sue Murray, Margit Mahlapuu
BMC Medicine - 2026 -
Programmable iPSC-derived CAR-NK vesicles remodel the immune microenvironment and eradicate
tumors
Hao Zhang, Shenglong Li, Chongzhong Liu, Xiangdong Gongye, Han Li, Yiyi Ji, Cheng Wei Ju, Wenzhen Jia, Xing Niu, Yujing Guan, Xiangyu Zhai, Bin Jin, Peng Xia
Cell Reports Medicine - 2026 -
Tumor-derived exosomal CCT6A serves as a matchmaker introducing chemokines to tumor-associated macrophages in pancreatic ductal
adenocarcinoma
Tianyin Ma, Wing-Wa Guo, Minghe Zhang, Wenzhi He, Cairang Dongzhi, Xiangdong Gongye, Peng Xia, Yibo Chai, Zhang Chen, Yimin Zhu, Chengming Qu, Jie Liu, Zhiyong Yang, Weijie Ma, Ming Tian, Yufeng Yuan
CELL DEATH & DISEASE - 2025 -
Machine Learning-Based WGCNA Approach for Developing an Immunogenic Cell Death-Related Hub Gene Signature and Identification of AJM1 as a Prognostic Biomarker in Pancreatic
Adenocarcinoma
Tianyin Ma, Xiangdong Gongye, Cairang Dongzhi, Yibo Chai, Qikun Wang, Ming Tian
International Journal of Medical Sciences - 2025 -
WDR4 drives tumour-associated macrophage reprogramming and tumour progression via selective translation and membrane cholesterol
efflux
Jie Liu, Chengming Qu, Yingyi Liu, Xiangdong Gongye, Minghe Zhang, Tianyin Ma, Wenzhi He, Haitao Wang, Xi Chen, Peng Xia, Yufeng Yuan
Nature Cell Biology - 2025 -
The Acetyltransferase ARD1 Induces Glutathione Synthesis to Facilitate Ferroptosis Evasion in Hepatocellular
Carcinoma
Yingyi Liu, Fusheng Liu, Jie Liu, Dongzhi Cairang, Xiaomian Li, Peng Xia, Weijie Ma, Tiangen Wu, Xiangdong Gongye, Zhonglin Zhang, Xi Chen, Wenzhi He, Yufeng Yuan
CANCER RESEARCH - 2025 -
Inhibition of GCKIII kinases STK25 and MST3 mitigates organ lipotoxicity and enhances metabolic resilience under nutritional
stress
Emma Andersson, Xiangdong Gongye, Emmelie Cansby, Jingjing Zhang, Mara Caputo, Bernice Asiedu, Viktor Garellick, Sheri Booten, Sue Murray, Ferran Font, Johan Ruud, Dan Lind, Manoj Amrutkar, Brian W. Howell, Ingrid Wernstedt Asterholm, Margit Mahlapuu
BMC MEDICINE - 2025