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High baseline PD-1+CD8 T Cells and TIGIT+CD8 T Cells in circulation associated with response to PD-1 blockade in patients with non-small cell lung
cancer
Nikita Dutta, Johanna Svensson, George-Alehandro Saad, Marielle Mello, Ella Äng, Ilayda Altinönder, Per Torstensson, Volkan Sayin, Anna Rohlin, Herve Luche, Andreas Hallqvist, Sukanya Raghavan
CANCER IMMUNOLOGY IMMUNOTHERAPY - 2025 -
Monotherapy With Immune Checkpoint Blockade Improves Survival Outcomes in KRAS-Mutant but Not KRAS Wild-Type Metastatic Lung Adenocarcinoma: Validation From an Extended Swedish
Cohort
Ella Äng, Sama Sayin, Jonas Smith Jonsson, Hannes Nilsson van Renswoude, Jan Nyman, Andreas Hallqvist, Clotilde Wiel, Volkan Sayin
JTO CLINICAL AND RESEARCH REPORTS - 2025 -
Comprehensive genetic variant analysis reveals combination of KRAS and LRP1B as a predictive biomarker of response to immunotherapy in patients with non-small cell lung
cancer.
Ella Äng Eklund, Johanna Svensson, Louise Stauber Näslund, Maria Yhr, Sama I Sayin, Clotilde Wiel, Levent Akyürek, Per Torstensson, Volkan I. Sayin, Andreas Hallqvist, Sukanya Raghavan, Anna Rohlin
Journal of Experimental & Clinical Cancer Research - 2025 -
Equalizing prognostic disparities in KRAS-mutated stage III NSCLC patients: addition of durvalumab to combined chemoradiotherapy improves
survival.
Ella A Eklund, Mathilda Orgard, Delice Wallin, Sama I Sayin, Henrik Fagman, Johan Isaksson, Sukanya Raghavan, Levent Akyürek, Jan Nyman, Clotilde Wiel, Andreas Hallqvist, Volkan I. Sayin
Lung Cancer - 2025 -
Distinct metastatic organotropism shapes prognosis in lung adenocarcinoma with brain
metastasis
Sama I Sayin, Ella M. Eklund, Kevin X. Ali, Jozefina J. Dzanan, Moe Xylander, Martin Dankis, Per Lindahl, Volkan I. Sayin, Andreas Hallqvist, Clotilde Wiel
FRONTIERS IN ONCOLOGY - 2025 -
Assessing the prognostic value of KRAS mutation combined with tumor size in stage I-II non-small cell lung cancer: a retrospective
analysis
Ella A Eklund, Ali Mourad, Clotilde Wiel, Sama I. Sayin, Henrik Fagman, Andreas Hallqvist, Volkan I. Sayin
Frontiers in Oncology - 2024 -
Pulmonary adenocarcinoma in situ and minimally invasive adenocarcinomas in European patients have less KRAS and more EGFR mutations compared to advanced
adenocarcinomas.
Jennie Petterson, Dyar Mustafa, Sashidar Bandaru, Ella Äng Eklund, Andreas Hallqvist, Volkan I. Sayin, Andréanne Gagné, Henrik Fagman, Levent Akyürek
International Journal of Molecular Sciences - 2024 -
Excessive copper impairs intrahepatocyte trafficking and secretion of selenoprotein
P.
Maria Schwarz, Caroline E Meyer, Alina Löser, Kristina Lossow, Julian Hackler, Christiane Ott, Susanne Jäger, Isabelle Mohr, Ella A Eklund, Angana A. H. Patel, Nadia Gul, Samantha Alvarez, Ilayda Altinonder, Clotilde Wiel, Maria Maares, Hajo Haase, Anetta Härtlova, Tilman Grune, Matthias B Schulze, Tanja Schwerdtle, Uta Merle, Hans Zischka, Volkan I. Sayin, Lutz Schomburg, Anna P Kipp
Nature communications - 2023 -
Combinatory analysis of immune cell subsets and tumor-specific genetic variants predict clinical response to PD-1 blockade in patients with non-small cell lung
cancer
Nikita Dutta, Anna Rohlin, Ella A Eklund, Maria K Magnusson, Frida Nilsson, Levent Akyürek, Per Torstensson, Volkan I. Sayin, Anna Lundgren, Andreas Hallqvist, Sukanya Raghavan
Frontiers in Oncology - 2023 -
KRAS mutations impact clinical outcome in metastatic non-small cell lung
cancer.
Ella A Eklund, Clotilde Wiel, Henrik Fagman, Levent Akyürek, Sukanya Raghavan, Jan Nyman, Andreas Hallqvist, Volkan I. Sayin
Cancers - 2022 -
Genomic profiling of the transcription factor Zfp148 and its impact on the p53
pathway
Zhiyuan V. Zou, Nadia Gul, Markus Lindberg, Abdulmalik Bokhari, Ella M. Eklund, Viktor Garellick, Angana A. H. Patel, Jozefina J. Dzanan, Ben Titmuss, Kristell Le Gal, Inger Johansson, Åsa Tivesten, Eva Forssell-Aronsson, Martin O. Bergö, Anna Staffas, Erik Larsson, Volkan I. Sayin, Per Lindahl
Scientific Reports - 2020