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- Sima Kumari
Sima Kumari
Postdoctor
Department of Medical Biochemistry and Cell-
Silencing of STE20-type kinase TAOK1 confers protection against hepatocellular lipotoxicity through metabolic
rewiring
Ying Xia, Emma Andersson, Sumit Kumar Anand, Emmelie Cansby, Mara Caputo, Sima Kumari, R. Porosk, K. Kilk, S. Nair, Hanns-Ulrich Marschall, M. Blüher, Margit Mahlapuu
Hepatology communications. - 2023 -
Silencing of STE20-type kinase STK25 in human aortic endothelial and smooth muscle cells is
atheroprotective
Emmelie Cansby, Sima Kumari, Mara Caputo, Ying Xia, Rando Porosk, Jonathan Robinson, Hao Wang, Britt-Marie Olsson, Josefine Vallin, Julie Grantham, Ursel Soomets, L. Thomas Svensson, Carina Sihlbom, Hanns-Ulrich Marschall, Andreas Edsfeldt, Isabel Goncalves, Margit Mahlapuu
Communications Biology - 2022 -
Inhibition of MAP4K4 signaling initiates metabolic reprogramming to protect hepatocytes from lipotoxic
damage
Sumit Kumar Anand, Mara Caputo, Ying Xia, Emma Andersson, Emmelie Cansby, Sima Kumari, Marcus Henricsson, R. Porosk, Katharina Keuenhof, Johanna L Höög, Syam Nair, Hanns-Ulrich Marschall, M. Bluher, Margit Mahlapuu
Journal of Lipid Research - 2022 -
Antagonizing STK25 Signaling Suppresses the Development of Hepatocellular Carcinoma Through Targeting Metabolic, Inflammatory, and Pro-Oncogenic
Pathways
Yeshwant Kurhe, Mara Caputo, Emmelie Cansby, Ying Xia, Sima Kumari, Sumit Kumar Anand, B. W. Howell, Hanns-Ulrich Marschall, Margit Mahlapuu
Cellular and Molecular Gastroenterology and Hepatology - 2022 -
Silencing of STE20-type kinase MST3 in mice with antisense oligonucleotide treatment ameliorates diet-induced nonalcoholic fatty liver
disease
Mara Caputo, Yeshwant Kurhe, Sima Kumari, Emmelie Cansby, M. Amrutkar, E. Scandalis, S. L. Booten, Marcus Ståhlman, Jan Borén, Hanns-Ulrich Marschall, M. Aghajan, Margit Mahlapuu
FASEB Journal - 2021 -
STE20-Type Protein Kinase MST4 Controls NAFLD Progression by Regulating Lipid Droplet Dynamics and Metabolic Stress in
Hepatocytes
Mara Caputo, Emmelie Cansby, Sima Kumari, Yeshwant Kurhe, Syam Nair, Marcus Ståhlman, Nagaraj M. Kulkarni, Jan Borén, Hanns-Ulrich Marschall, M. Bluher, Margit Mahlapuu
Hepatology Communications - 2021