Sebastian Valenzuela
Doctoral Student
Department of Medical Biochemistry and Cell-
Pathological variants in TOP3A cause distinct disorders of mitochondrial and nuclear genome
stability
Direnis Erdinc, A. Rodriguez-Luis, M. R. Fassad, S. Mackenzie, C. M. Watson, Sebastian Valenzuela, Xie Xie, K. E. Menger, K. Sergeant, K. Craig, S. Hopton, G. Falkous, J. Poulton, H. Garcia-Moreno, P. Giunti, C. A. D. Aschoff, J. A. M. Saute, A. J. Kirby, C. Toro, L. Wolfe, D. Novacic, L. Greenbaum, A. Eliyahu, O. Barel, Y. Anikster, R. McFarland, G. S. Gorman, A. M. Schaefer, Claes M Gustafsson, R. W. Taylor, Maria Falkenberg, T. J. Nicholls
Embo Molecular Medicine - 2023 -
Article Non-coding 7S RNA inhibits transcription via mitochondrial RNA polymerase
dimerization
Xuefeng Zhu, Xie Xie, H. Das, Benedict Tan, Yonghong Shi, Ali Al-Behadili, Bradley Peter, E. Motori, Sebastian Valenzuela, Viktor Posse, Claes M Gustafsson, B. M. Hallberg, Maria Falkenberg
Cell - 2022 -
DNA polymerase gamma mutations that impair holoenzyme stability cause catalytic subunit
depletion
P. Silva-Pinheiro, Carlos Pardo-Hernandez, A. Reyes, L. Tilokani, Anup Mishra, R. Cerutti, S. F. Li, D. H. Rozsivalova, Sebastian Valenzuela, S. A. Dogan, Bradley Peter, P. Fernandez-Silva, A. Trifunovic, J. Prudent, M. Minczuk, L. Bindoff, Bertil Macao, M. Zeviani, Maria Falkenberg, C. Viscomi
Nucleic Acids Research - 2021