Andrew Ewing

Professor

Department of Chemistry & Molecular

Biology

Mail

andrew.ewing@gu.se

Fax

+46 31-772 34 99

Visiting address

Kemigården 4

41258 Göteborg

Room number

4031

Postal address

Kemivägen 10

41296 Göteborg

About Andrew Ewing

RESEARCH Electrochemistry, imaging with optical (STED) and mass spectrometry (SIMS, NanoSIMS) methods aimed at understanding the chemistry of single nerve cells, single vesicles, neural communication in cell networks and in the Drosophila nervous system; and understanding molecular messengers in cell differentiation. Analytical chemistry methods at the micro- and nanoscale.

Links

Ewing group home page: www.andrewewinggroup.se/
Analytical Chemistry home page: www.cmb.gu.se/english/research/analytical-chemistry/

TEACHING

Graduate classes: Bioanalytical electrochemistry, spectroscopy and mass spectrometry, analytical separations

Undergraduate classes: Analytical chemistry and Bioanalytical Chemistry

Publications

Striatal Dopamine Transporter Function Is Facilitated by Converging Biology of alpha-Synuclein and
Cholesterol

S. Threlfell, A. S. Mohammadi, B. J. Ryan, N. Connor-Robson, N. J. Platt, R. Anand, F. Serres, T. Sharp, N. Bengoa-Vergniory, R. Wade-Martins, Andrew G Ewing, S. J. Cragg, K. R. Brimblecombe
Frontiers in Cellular Neuroscience - 2021-01-01
Nanoscale Amperometry Reveals that Only a Fraction of Vesicular Serotonin Content is Released During Exocytosis from Beta
Cells

Amir Hatamie, Lin Ren, Haiqiang Dou, Nikhil Gandasi, Patrik Rorsman, Andrew G Ewing
Angewandte Chemie-International Edition - 2021-01-01
Chemical Analysis of Single Cells and
Organelles

Keke Hu, Tho D. K. Nguyen, Stefania Rabasco, Pieter E. Oomen, Andrew G Ewing
Analytical Chemistry - 2021-01-01
Mass spectrometric imaging of plasma membrane lipid alteration correlated with amperometrically measured activity-dependent plasticity in
exocytosis

Chaoyi Gu, Mai H. Philipsen, Andrew G Ewing
International Journal of Molecular Sciences - 2020-01-01
Zinc Deficiency Leads to Lipid Changes in Drosophila Brain Similar to Cognitive-Impairing Drugs: An Imaging Mass Spectrometry
Study

M. H. Philipsen, Chaoyi Gu, Andrew G Ewing
Chembiochem - 2020-01-01
Spatial Lipidomics Reveals Region and Long Chain Base Specific Accumulations of Monosialogangliosides in Amyloid Plaques in Familial Alzheimer's Disease Mice (5xFAD)
Brain.

Ibrahim Kaya, Eva Jennische, Johan Dunevall, Stefan Lange, Andrew G Ewing, Per Malmberg, Ahmet Tarik Baykal, John S. Fletcher
ACS chemical neuroscience - 2020-01-01
COVID-19—a very visible
pandemic

Andrew G Ewing
The Lancet - 2020-01-01
Mass Spectrometry Imaging of Cocaine, Drug Removal and Methylphenidate AlterPhospholipids in Drosophila
Brain

Mai H. Philipsen, Nhu TN Phan, John S. Fletcher, Andrew G Ewing
Biorxiv preprint - 2020-01-01
Nanoelectrochemical analysis inside a single living
cell

Xin-Wei Zhang, Amir Hatamie, Andrew G Ewing
Current Opinion in Electrochemistry - 2020-01-01
Correlating Molecule Count and Release Kinetics with Vesicular Size Using Open Carbon
Nanopipettes

Keke Hu, R. Jia, Amir Hatamie, Kim Vo, M. V. Mirkin, Andrew G Ewing
Journal of the American Chemical Society - 2020-01-01
Intracellular injection of phospholipids directly alters exocytosis and the fraction of chemical release in chromaffin cells as measured by
nano-electrochemistry

Mohaddeseh A. Aref, Elias Ranjbari, Armaghan Romiani, Andrew G Ewing
Chemical Science - 2020-01-01
Direct Measurement of Total Vesicular Catecholamine Content with Electrochemical Microwell
Arrays

Elias Ranjbari, Zahra Taleat, M. Mapar, Mohaddeseh A. Aref, Johan Dunevall, Andrew G Ewing
Analytical Chemistry - 2020-01-01
Comparison of Disk and Nanotip Electrodes for Measurement of Single-Cell Amperometry during Exocytotic
Release

Chaoyi Gu, Xin-Wei Zhang, Andrew G Ewing
Analytical Chemistry - 2020-01-01
Counteranions in the Stimulation Solution Alter the Dynamics of Exocytosis Consistent with the Hofmeister
Series

Xiulan He, Andrew G Ewing
Journal of the American Chemical Society - 2020-01-01
Subcellular Mass Spectrometry Imaging and Absolute Quantitative Analysis across
Organelles

Aurélien Thomen, Neda Najafinobar, Florent Penen, Emma Kay, Pratik P. Upadhyay, Xianchan Li, Nhu TN Phan, Per Malmberg, Magnus Klarqvist, Shalini Andersson, Michael E. Kurczy, Andrew G Ewing
ACS nano - 2020-01-01
Intracellular Electrochemical Nanomeasurements Reveal that Exocytosis of Molecules at Living Neurons is Subquantal and
Complex

Anna Larsson, Soodabeh Majdi, A. Oleinick, I. Svir, Johan Dunevall, C. Amatore, Andrew G Ewing
Angewandte Chemie-International Edition - 2020-01-01
Interplay between Cocaine, Drug Removal, and Methylphenidate Reversal on Phospholipid Alterations in Drosophila Brain Determined by Imaging Mass
Spectrometry

Mai H. Philipsen, Nhu TN Phan, John S. Fletcher, Andrew G Ewing
ACS Chemical Neuroscience - 2020-01-01
Simultaneous Quantification of Vesicle Size and Catecholamine Content by Resistive Pulses in Nanopores and Vesicle Impact Electrochemical
Cytometry

Xin-Wei Zhang, Amir Hatamie, Andrew G Ewing
Journal of the American Chemical Society - 2020-01-01
Amperometric Measurements and Dynamic Models Reveal a Mechanism for How Zinc Alters Neurotransmitter
Release

Lin Ren, A. Oleinick, I. Svir, C. Amatore, Andrew G Ewing
Angewandte Chemie-International Edition - 2020-01-01
Outcomes following small bowel obstruction due to malignancy in the national audit of small bowel
obstruction

Thomas M. Drake, Matthew J. Lee, Adele E. Sayers, John Abercrombie, Austin Acheson, Derek Alderson, Iain Anderson, Mike Bradburn, Michael Davies, Zaed Hamady, Daniel Hind, Marianne Hollyman, Sarah Hare, Ellen Lee, John Northover, Christopher Lewis, Paul J. Marriott, Nick Maynard, Malcolm McFall, Aravinth Muragananthan, David Murray, Pritam Singh, Gillian Tierney, Azmina Verjee, Ciaran Walsh, Jonathan RL Wild, Timothy Wilson, S. Abbott, Y. Abdulaal, S. Afshar, M. Akhtar, D. Anderson, S. Appleton, D. Bandyopadhyay, G. Bashir, N. Behar, S. Bhandari, G. Branagan, R. Boulton, C. Borg, G. Bouras, J. Boyle, H. Brewer, L. Brown, C. Briggs, M. Cartmell, S. Chan, N. Chandratreya, P. Conaghan, J. Cornish, D. Cotton, P. Coyne, J. Crozier, T. Cook, P. Cunha, N. Curtis, A. Day, S. Dayal, R. Dennis, P. Dent, H. Dowson, R. Fallaize, S. Farag, M. El Farran, G. Faulkner, P. Giordano, T. Grey, V. Halahakoon, J. Hannay, A. Harikrishnan, S. Holtham, P. Hawkin, C. Hall, L. Hancock, J. Hartley, F. Howse, R. Kallam, G. Kakaniaris, S. Kelly, S. Lockwood, D. Leinhardt, B. Levy, R. Lal, T. Lazim, J. Lund, R. Lunevicius, P. Mathur, K. Maude, D. McArthur, B. McIlroy, A. Miles, S. Moug, M. Mondragon-Pritchard, D. Messenger, M. Mullan, A. Myers, K. Muhammad, C. Mason, J. Sarveswaran, V. Shatkar, Andrew G Ewing
European Journal of Surgical Oncology - 2019-01-01
Vesicular Transmitter Content in Chromaffin Cells Can Be Regulated via Extracellular
ATP

Anna Larsson, Soodabeh Majdi, R. Borges, Andrew G Ewing
ACS Chemical Neuroscience - 2019-01-01
Mass spectrometry imaging as a novel approach to measure hippocampal
zinc

M. D. Pour, L. Ren, Eva Jennische, Stefan Lange, Andrew G Ewing, P. Malmberg
Journal of Analytical Atomic Spectrometry - 2019-01-01
Plasticity in exocytosis revealed through the effects of repetitive stimuli affect the content of nanometer vesicles and the fraction of transmitter
released

Chaoyi Gu, Anna Larsson, Andrew G Ewing
Proceedings of the National Academy of Sciences of the United States of America - 2019-01-01
Analytical Techniques: Shedding Light upon Nanometer-Sized Secretory
Vesicles

Elias Ranjbari, Soodabeh Majdi, Andrew G Ewing
Trends in Chemistry - 2019-01-01
Extracellular ATP regulates the vesicular pore opening in chromaffin cells and increases the fraction released during individual exocytosis
events

Soodabeh Majdi, Anna Larsson, N. Najafinobar, R. Borges, Andrew G Ewing
ACS Chemical Neuroscience - 2019-01-01
Dopamine release dynamics in the tuberoinfundibular dopamine
system.

Stefanos Stagkourakis, Johan Dunevall, Zahra Taleat, Andrew G Ewing, Christian Broberger
The Journal of neuroscience : the official journal of the Society for Neuroscience - 2019-01-01
Anticancer Drug Tamoxifen Affects Catecholamine Transmitter Release and Storage from Single
Cells.

Zahra Taleat, Anna Larsson, Andrew G Ewing
ACS chemical neuroscience - 2019-01-01
Altered Lipid Composition of Secretory Cells Following Exposure to Zinc Can Be Correlated to Changes in
Exocytosis

Lin Ren, Masoumeh Dowlatshahi Pour, Per Malmberg, Andrew G Ewing
Chemistry - A European Journal - 2019-01-01
Combined Amperometry and Electrochemical Cytometry Reveal Differential Effects of Cocaine and Methylphenidate on Exocytosis and the Fraction of Chemical
Release

Wanying Zhu, Chaoyi Gu, Johan Dunevall, Lin Ren, Xuemin Zhou, Andrew G Ewing
Angewandte Chemie - International Edition - 2019-01-01
Chemical Analysis of Single
Cells

Pieter E. Oomen, Mohaddeseh A. Aref, Ibrahim Kaya, Nhu TN Phan, Andrew G Ewing
Analytical Chemistry - 2019-01-01
Using Single-Cell Amperometry and Intracellular Vesicle Impact Electrochemical Cytometry to Shed Light on the Biphasic Effects of Lidocaine on
Exocytosis

Daixin Ye, Chaoyi Gu, Andrew G Ewing
ACS Chemical Neuroscience - 2018-01-01
Frontiers in
Neurochemistry

Andrew G Ewing, Insung S. Choi, William Green, Orit Shefi
ChemPhysChem - 2018-01-01
On-Tissue Chemical Derivatization of Catecholamines Using 4-(N-Methyl)pyridinium Boronic Acid for ToF-SIMS and LDI-ToF Mass Spectrometry
Imaging

Ibrahim Kaya, S. M. Brülls, Johan Dunevall, Eva Jennische, Stefan Lange, J. Martensson, Andrew G Ewing, Per Malmberg, John S. Fletcher
Analytical Chemistry - 2018-01-01
Relative quantification of deuterated omega-3 and-6 fatty acids and their lipid turnover in PC12 cell membranes using
TOF-SIMS

Mai H. Philipsen, P. Malmberg, Andrew G Ewing, V. P. Nada
Journal of Lipid Research - 2018-01-01
Electrochemical quantification of transmitter concentration in single nanoscale vesicles isolated from PC12
cells

Xianchan Li, J. Dunevall, Andrew G Ewing
Faraday Discussions - 2018-01-01
Benefits of NaCl addition for time-of-flight secondary ion mass spectrometry analysis including the discrimination of diacylglyceride and triacylglyceride
ions

S. Samfors, Andrew G Ewing, John S. Fletcher
Rapid Communications in Mass Spectrometry - 2018-01-01
Mass Spectrometry Imaging Suggests That Cisplatin Affects Exocytotic Release by Alteration of Cell Membrane
Lipids

Amir Saeid Mohammadi, Xianchan Li, Andrew G Ewing
Analytical Chemistry - 2018-01-01
Mass Spectrometry Imaging Shows Cocaine and Methylphenidate Have Opposite Effects on Major Lipids in Drosophila
Brain

Mai H. Philipsen, Nhu TN Phan, John S. Fletcher, Per Malmberg, Andrew G Ewing
Acs Chemical Neuroscience - 2018-01-01
Electrochemistry in and of the Fly
Brain

Soodabeh Majdi, Anna Larsson, M. Philipsen, Andrew G Ewing
Electroanalysis - 2018-01-01
On the Action of General Anesthetics on Cellular Function: Barbiturate Alters the Exocytosis of Catecholamines in a Model Cell
System

Daixin Ye, Andrew G Ewing
Chemphyschem - 2018-01-01
Nanopore Opening at Flat and Nanotip Conical Electrodes during Vesicle Impact Electrochemical
Cytometry

Xianchan Li, L. Ren, J. Dunevall, Daixin Ye, H. S. White, M. A. Edwards, Andrew G Ewing
ACS Nano - 2018-01-01
Electrochemical Investigation of the Interaction between Catecholamines and
ATP

Z. Taleat, J. Estevez-Herrera, J. D. Machado, J. Dunevall, Andrew G Ewing, R. Borges
Analytical Chemistry - 2018-01-01
MS/MS analysis and imaging of lipids across Drosophila brain using secondary ion mass
spectrometry

Nhu TN Phan, Marwa Munem, Andrew G Ewing, John S. Fletcher
Analytical and Bioanalytical Chemistry - 2017-01-01
Measuring synaptic vesicles using cellular electrochemistry and nanoscale molecular
imaging

Nhu TN Phan, Xianchan Li, Andrew G Ewing
Nature Reviews Chemistry - 2017-01-01
Vesicle impact electrochemical cytometry compared to amperometric exocytosis
measurements

J. Dunevall, Soodabeh Majdi, Anna Larsson, Andrew G Ewing
Current Opinion in Electrochemistry - 2017-01-01
Zinc Regulates Chemical-Transmitter Storage in Nanometer Vesicles and Exocytosis Dynamics as Measured by
Amperometry

Lin Ren, Masoumeh Dowlatshahi Pour, Soodabeh Majdi, Xianchan Li, Per Malmberg, Andrew G Ewing
Angewandte Chemie - International Edition - 2017-01-01
DMSO Chemically Alters Cell Membranes to Slow Exocytosis and Increase the Fraction of Partial Transmitter
Released

Soodabeh Majdi, N. Najafinobar, J. Dunevall, J. Lovric, Andrew G Ewing
Chembiochem - 2017-01-01
Mechanistic Aspects of Vesicle Opening during Analysis with Vesicle Impact Electrochemical
Cytometry

Xianchan Li, J. Dunevall, L. Ren, Andrew G Ewing
Analytical Chemistry - 2017-01-01
Nano Secondary Ion Mass Spectrometry Imaging of Dopamine Distribution Across Nanometer
Vesicles

Jelena Lovrić, Johan Dunevall, Anna Larsson, Lin Ren, S. Andersson, A. Meibom, Per Malmberg, M.E. Kurczy, Andrew G Ewing
ACS Nano - 2017-01-01
Laser Desorption Ionization Mass Spectrometry Imaging of Drosophila Brain Using Matrix Sublimation versus Modification with
Nanoparticles

Nhu TN Phan, Amir Saeid Mohammadi, Masoumeh Dowlatshahi Pour, Andrew G Ewing
Analytical Chemistry - 2016-01-01
Intact lipid imaging of mouse brain samples: MALDI, nanoparticle-laser desorption ionization, and 40 keV argon cluster secondary ion mass
spectrometry

Amir Saeid Mohammadi, Nhu TN Phan, John S. Fletcher, Andrew G Ewing
Analytical and Bioanalytical Chemistry - 2016-01-01
Mass spectrometric profiling of lipids in intestinal tissue from rats fed cereals processed for medical
conditions

Masoumeh Dowlatshahi Pour, Eva Jennische, Stefan Lange, Andrew G Ewing, Per Malmberg
Biointerphases - 2016-01-01
An investigation on the mechanism of sublimed DHB matrix on molecular ion yields in SIMS imaging of brain
tissue

Masoumeh Dowlatshahi Pour, Per Malmberg, Andrew G Ewing
Analytical and Bioanalytical Chemistry - 2016-01-01
Cysteine residues reduce the severity of dopamine electrochemical
fouling

Wolfgang Harreither, Raphaël Trouillon, Philippe Poulin, Wilfrid Neri, Andrew G Ewing, Gulnara Safina
Electrochimica Acta - 2016-01-01
Multimodal Imaging of Chemically Fixed Cells in Preparation for
NanoSIMS

Jelena Lovric, Per Malmberg, Bengt R Johansson, John S. Fletcher, Andrew G Ewing
Analytical Chemistry - 2016-01-01
Using Single-Cell Amperometry To Reveal How Cisplatin Treatment Modulates the Release of Catecholamine Transmitters during
Exocytosis

Xianchan Li, Johan Dunevall, Andrew G Ewing
Angewandte Chemie-International Edition - 2016-01-01
Quantitative Chemical Measurements of Vesicular Transmitters with Electrochemical
Cytometry

Xianchan Li, Johan Dunevall, Andrew G Ewing
Accounts of Chemical Research - 2016-01-01
On the mechanism of electrochemical vesicle cytometry: chromaffin cell vesicles and
liposomes

J. Lovric, N. Najaiinobar, J. Dunevall, Soodabeh Majdi, I. Svir, A. Oleinick, C. Amatore, Andrew G Ewing
Faraday Discussions - 2016-01-01
Single cell amperometry reveals curcuminoids modulate the release of neurotransmitters during exocytosis from PC12
cells

Xianchan Li, A. S. Mohammadi, Andrew G Ewing
Journal of Electroanalytical Chemistry - 2016-01-01
The evidence for open and closed exocytosis as the primary release
mechanism

Lin Ren, Lisa J. Mellander, Jacqueline Keighron, Ann-Sofie Cans, Michael E. Kurczy, I. Svir, A. Oleinick, C. Amatore, Andrew G Ewing
Quarterly Reviews of Biophysics - 2016-01-01
Excited Fluorophores Enhance the Opening of Vesicles at Electrode Surfaces in Vesicle Electrochemical
Cytometry

N. Najafinobar, J. Lovrić, Soodabeh Majdi, J. Dunevall, A. S. Cans, Andrew G Ewing
Angewandte Chemie International Edition - 2016-01-01
Lithographic Microfabrication of a 16-Electrode Array on a Probe Tip for High Spatial Resolution Electrochemical Localization of
Exocytosis

Joakim Wigström, Johan Dunevall, Neda Najafinobar, Jelena Lovric, Jun Wang, Andrew G Ewing, Ann-Sofie Cans
Analytical Chemistry - 2016-01-01
Food-induced changes of lipids in rat neuronal tissue visualized by ToF-SIMS
imaging

M. D. Pour, Eva Jennische, Stefan Lange, Andrew G Ewing, Per Malmberg
Scientific Reports - 2016-01-01
Cell Analysis with Bioelectrochemical Approaches: Past, Present, and
Future

Andrew G Ewing
Electrochemistry - 2016-01-01
Lipid Structural Effects of Oral Administration of Methylphenidate in Drosophila Brain by Secondary Ion Mass Spectrometry
Imaging

Nhu TN Phan, John S. Fletcher, Andrew G Ewing
Analytical Chemistry - 2015-01-01
Characterizing the Catecholamine Content of Single Mammalian Vesicles by Collision-Adsorption Events at an
Electrode

Johan Dunevall, Hoda Mashadi Fathali, Neda Najafinobar, Jelena Lovric, Joakim Wigström, Ann-Sofie Cans, Andrew G Ewing
Journal of the American Chemical Society - 2015-01-01
Spatial neuroproteomics using imaging mass
spectrometry

Jörg Hanrieder, Per Malmberg, Andrew G Ewing
Biochimica Et Biophysica Acta-Proteins and Proteomics - 2015-01-01
Selected recent in vivo studies on chemical measurements in
invertebrates

Soodabeh Majdi, Lin Ren, Hoda Mashadi Fathali, Xianchan Li, Andrew G Ewing
Analyst - 2015-01-01
Quantitative Measurement of Transmitters in Individual Vesicles in the Cytoplasm of Single Cells with Nanotip
Electrodes

Xianchan Li, Soodabeh Majdi, Johan Dunevall, Hoda Mashadi Fathali, Andrew G Ewing
Angewandte Chemie International Edition - 2015-01-01
Electrochemical Measurements of Optogenetically Stimulated Quantal Amine Release from Single Nerve Cell Varicosities in Drosophila
Larvae

Soodabeh Majdi, E Carina Berglund, Johan Dunevall, A. I. Oleinick, C. Amatore, D. E. Krantz, Andrew G Ewing
Angewandte Chemie International Edition - 2015-01-01
Neuronal Networks on Nanocellulose
Scaffolds

M. Jonsson, Christian Brackmann, Maja Puchades, K. Brattås, Andrew G Ewing, Paul Gatenholm, Annika Enejder
Tissue Engineering. Part C, Methods - 2015-01-01
The Effect of Excited Fluorophore on Vesicle Fusion at the Surface of the
Electrode

Neda Najafinobar, Johan Dunevall, Jelena Lovric, Hoda Mashadi Fathali, Andrew G Ewing, Ann-Sofie Cans
Biophysical Journal - 2015-01-01
Imaging Mass Spectrometry for Single-Cell
Analysis

Nhu TN Phan, John S. Fletcher, Andrew G Ewing
Reference Module in Chemistry, Molecular Sciences and Chemical Engineering - 2014-01-01
Two modes of exocytosis in an artificial
cell

Lisa J. Mellander, Michael E. Kurczy, Neda Najafinobar, Johan Dunevall, Andrew G Ewing, Ann-Sofie Cans
Scientific Reports - 2014-01-01
Actin Controls the Vesicular Fraction of Dopamine Released During Extended Kiss and Run
Exocytosis

Raphaël Trouillon, Andrew G Ewing
Acs Chemical Biology - 2014-01-01
Simultaneous study of subcellular exocytosis with individually addressable multiple
microelectrodes

Jun Wang, Andrew G Ewing
Analyst - 2014-01-01
Spatial Elucidation of Spinal Cord Lipid- and Metabolite-Regulations in Amyotrophic Lateral
Sclerosis

Jörg Hanrieder, Andrew G Ewing
Scientific Reports - 2014-01-01
High Resolution Metabolite Imaging in the Hippocampus Following Neonatal Exposure to the Environmental Toxin BMAA Using
ToF-SIMS

Jörg Hanrieder, Lorenz Gerber, Åsa P Sandelius, Eva B. Brittebo, Andrew G Ewing, Oskar Karlsson
Acs Chemical Neuroscience - 2014-01-01
Development of an Organic Lateral Resolution Test Device for Imaging Mass
Spectrometry

M. K. Passarelli, Jun Wang, Amir Saeid Mohammadi, Raphaël Trouillon, I. Gilmore, Andrew G Ewing
Analytical Chemistry - 2014-01-01
Probing the lipid chemistry of neurotoxin-induced hippocampal lesions using multimodal imaging mass
spectrometry

Jörg Hanrieder, K. Oskar, E. B. Brittebo, Per Malmberg, Andrew G Ewing
Surface and Interface Analysis: 19th International Conference on Secondary Ion Mass Spectrometry (SIMS) - 2014-01-01
ToF-SIMS imaging of lipids and lipid related compounds in Drosophila
brain

Nhu TN Phan, John S. Fletcher, Peter Sjövall, Andrew G Ewing
Surface and Interface Analysis: 19th International Conference on Secondary Ion Mass Spectrometry (SIMS) - 2014-01-01
Analysis of liposome model systems by time-of-flight secondary ion mass
spectrometry

Jelena Lovric, Jacqueline Keighron, Tina B. Angerer, Xianchan Li, Per Malmberg, John S. Fletcher, Andrew G Ewing
Surface and Interface Analysis: 19th International Conference on Secondary Ion Mass Spectrometry (SIMS) - 2014-01-01
Gold and silver nanoparticle-assisted laser desorption ionization mass spectrometry compatible with secondary ion mass spectrometry for lipid
analysis

Amir Saeid Mohammadi, John S. Fletcher, Per Malmberg, Andrew G Ewing
Surface and Interface Analysis: 19th International Conference on Secondary Ion Mass Spectrometry (SIMS) - 2014-01-01
Spatial Resolution of Single-Cell Exocytosis by Microwell-Based Individually Addressable Thin Film Ultramicroelectrode
Arrays

Jun Wang, Raphaël Trouillon, Johan Dunevall, Andrew G Ewing
Analytical Chemistry - 2014-01-01
Applying THz Technology in Life
Science

Helena Rodilla, Josip Vukusic, Jan Stake, Anna Kim, Gavin Jeffries, Aldo Jesorka, Junsheng Yang, Ida Lundholm, Weixiao Yuan Wahlgren, Åsa Persson, Gergely Katona, Richard Neutze, Thomas Nyström, Andrew G Ewing
Swedish Microwave Days. Gigahertz Symposium, March 11-12, 2014. Gothenburg, Sweden - 2014-01-01
Using imaging ToF-SIMS data to determine the cell wall thickness of fibers in
wood

Lorenz Gerber, V. M. Hoang, L. Tran, H. A. T. Kiet, Per Malmberg, Jörg Hanrieder, Andrew G Ewing
Surface and Interface Analysis: 19th International Conference on Secondary Ion Mass Spectrometry (SIMS) - 2014-01-01
Pituitary Adenylate Cyclase Activating Polypeptide Modulates Catecholamine Storage and Exocytosis in PC12
Cells

Y. Dong, G. Ning, Andrew G Ewing, M. L. Heien, V. P. Lifornia
Plos One - 2014-01-01
Mass spectrometry imaging of freeze-dried membrane phospholipids of dividing Tetrahymena
pyriformis

Ingela Lanekoff, Nhu TN Phan, C. T. Van Bell, N. Winograd, Peter Sjövall, Andrew G Ewing
Surface and Interface Analysis - 2013-01-01
Capillary Electrophoresis-Mass Spectrometry-Based Detection of Drugs and Neurotransmitters in Drosophila
Brain

Nhu TN Phan, Jörg Hanrieder, Carina Berglund, Andrew G Ewing
Analytical Chemistry - 2013-01-01
Imaging mass spectrometry in
neuroscience.

Jörg Hanrieder, Nhu TN Phan, Michael E. Kurczy, Andrew G Ewing
ACS chemical neuroscience - 2013-01-01
Oral administration of methylphenidate blocks the effect of cocaine on uptake at the Drosophila dopamine
transporter.

E Carina Berglund, Monique A Makos, Jacqueline Keighron, Nhu TN Phan, Michael L Heien, Andrew G Ewing
ACS chemical neuroscience - 2013-01-01
Single-Cell Lipidomics: Characterizing and Imaging Lipids on the Surface of Individual Aplysia californica Neurons with Cluster Secondary Ion Mass
Spectrometry

M. K. Passarelli, Andrew G Ewing, N. Winograd
Analytical Chemistry - 2013-01-01
The real catecholamine content of secretory vesicles in the CNS revealed by electrochemical
cytometry

D. M. Omiatek, A. J. Bressler, Ann-Sofie Cans, A. M. Andrews, M. L. Heien, Andrew G Ewing
Scientific Reports - 2013-01-01
Single Cell Amperometry Reveals Glycocalyx Hinders the Release of Neurotransmitters During
Exocytosis

Raphaël Trouillon, Andrew G Ewing
Analytical Chemistry - 2013-01-01
C-60-SIMS studies of glycerophospholipid in a LIPID MAPS model system: KDO2-Lipid A stimulated RAW 264.7
cells

M. K. Passarelli, Andrew G Ewing, N. Winograd
Surface and Interface Analysis - 2013-01-01
Amperometric Measurements at Cells Support a Role for Dynamin in the Dilation of the Fusion Pore during
Exocytosis

Raphaël Trouillon, Andrew G Ewing
Chemphyschem - 2013-01-01
Time-of-Flight Secondary Ion Mass Spectrometry Based Molecular Histology of Human Spinal Cord Tissue and Motor
Neurons

Jörg Hanrieder, Per Malmberg, Olle R Lindberg, John S. Fletcher, Andrew G Ewing
Analytical Chemistry - 2013-01-01
Carbon Nanotube Fiber Microelectrodes Show a Higher Resistance to Dopamine
Fouling

Wolfgang Harreither, Raphaël Trouillon, P. Poulin, W. Neri, Andrew G Ewing, Gulnara Safina
Analytical Chemistry - 2013-01-01
Electrochemical measurements of transmitters in flies, at cells, and from transmitter
vesicles

Andrew G Ewing
Abstracts of Papers of the American Chemical Society (Conference: 246th National Meeting of the American-Chemical-Society (ACS)) - 2013-01-01
Spatial resolution of exocytosis across a single cell by a microwell-based individually addressable thin film ultra-microelectrode
array

Jun Wang, Raphaël Trouillon, Johan Dunevall, Andrew G Ewing
17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013; Freiburg; Germany; 27 October 2013 through 31 October 2013 - 2013-01-01
Evaluating the Diffusion Coefficient of Dopamine at the Cell Surface During Amperometric Detection: Disk vs Ring
Microelectrodes

R. Trouillon, Y. Q. Lin, Lisa J. Mellander, Jacqueline Keighron, Andrew G Ewing
Analytical Chemistry - 2013-01-01
Individually Addressable Thin-Film Ultramicroelectrode Array for Spatial Measurements of Single Vesicle
Release

J. Wang, R. Trouillon, Y. Q. Lin, M. I. Svensson, Andrew G Ewing
Analytical Chemistry - 2013-01-01
C60-ToF SIMS imaging of frozen hydrated HeLa
cells

A. M. Piwowar, S. Keskin, M. O. Delgado, K. Shen, J. J. Hue, Ingela Lanekoff, Andrew G Ewing, N. Winograd
Surface and Interface Analysis - 2013-01-01
Freeze-Drying as Sample Preparation for Micellar Electrokinetic Capillary Chromatography-Electrochemical Separations of Neurochemicals in Drosophila
Brains

E. C. Berglund, N. J. Kuklinski, E. Karagunduz, Kubra Ucar, Jörg Hanrieder, Andrew G Ewing
Analytical Chemistry - 2013-01-01
Chemical Analysis of Single
Cells

Raphaël Trouillon, M. K. Passarelli, J. Wang, Michael E. Kurczy, Andrew G Ewing
Analytical Chemistry - 2013-01-01
Analytical tools to monitor exocytosis: A focus on new fluorescent probes and
methods

Jacqueline Keighron, Andrew G Ewing, Ann-Sofie Cans
Analyst - 2012-01-01
Carbon-Ring Microelectrode Arrays for Electrochemical Imaging of Single Cell Exocytosis: Fabrication and
Characterization

YQ Lin, R. Trouillon, M. Svensson, Jacqueline Keighron, Ann-Sofie Cans, Andrew G Ewing
Analytical Chemistry - 2012-01-01
Highlights of selected recent electrochemical measurements in living
systems

Raphaël Trouillon, Maria I. Svensson, Carina Berglund, Ann-Sofie Cans, Andrew G Ewing
Electrochimica Acta - 2012-01-01
Amperometric post spike feet reveal most exocytosis is via extended kiss-and-run
fusion

Lisa J. Mellander, Raphaël Trouillon, Maria I. Svensson, Andrew G Ewing
Scientific Reports - 2012-01-01
Ruthenium(II) Complex Enantiomers as Cellular Probes for Diastereomeric Interactions in Confocal and Fluorescence Lifetime Imaging
Microscopy

Frida Svensson, Maria Abrahamsson, N. Stromberg, Andrew G Ewing, Per Lincoln
Journal of Physical Chemistry Letters - 2011-01-01
Chemical Analysis of Single
Cells

Yuqing Lin, Raphaël Trouillon, Gulnara Safina, Andrew G Ewing
Analytical Chemistry - 2011-01-01
Relative quantification of phospholipid accumulation in the PC12 cell plasma membrane following phospholipid incubation using TOF-SIMS
Imaging.

Ingela Lanekoff, Peter Sjövall, Andrew G Ewing
Analytical Chemistry - 2011-01-01
Temporal Resolution in Electrochemical Imaging on Single PC12 Cells Using Amperometry and Voltammetry at Microelectrode
Arrays

B Zhang, MLAV Heien, MF Santillo, Lisa J. Mellander, Andrew G Ewing
ANALYTICAL CHEMISTRY - 2011-01-01
Mechanics of lipid bilayer junctions affecting the size of a connecting lipid
nanotube

Roger Karlsson, Michael E. Kurczy, R. Grzhibovskis, Kelly L. Adams, Andrew G Ewing, Ann-Sofie Cans, Marina V. Voinova
Nanoscale Research Letters - 2011-01-01
Highlights of 20 years of electrochemical measurements of exocytosis at cells and artificial
cells

Ann-Sofie Cans, Andrew G Ewing
Journal of Solid State Electrochemistry - 2011-01-01
An in situ fracture device to image lipids in single cells using
ToF-SIMS

Ingela Lanekoff, Michael E. Kurczy, Kelly L. Adams, J Malm, Roger Karlsson, P Sjovall, Andrew G Ewing
SURFACE AND INTERFACE ANALYSIS - 2011-01-01
Electrochemical Probes for Spatial Detection of Exocytosis and
Vesicles

Lisa J. Mellander, Ann-Sofie Cans, Andrew G Ewing
ChemPhysChem - 2010-01-01
Time of Flight Mass Spectrometry Imaging of Samples Fractured In Situ with a Spring-Loaded Trap
System.

Ingela Lanekoff, Michael E. Kurczy, Rowland Hill, John S. Fletcher, John C Vickerman, Nick Winograd, Peter Sjövall, Andrew G Ewing
Analytical chemistry - 2010-01-01
Tools to monitor exocytosis: a focus on new fluorescent probes and
methods

Ann-Sofie Cans, Andrew G Ewing
Cellscience Reviews - 2010-01-01
Steady-State Electrochemical Determination of Lipidic Nanotube Diameter Utilizing an Artificial Cell
Model

Kelly L. Adams, Johan Engelbrektsson, Marina V. Voinova, Bo Zhang, Daniel J. Eves, Roger Karlsson, Michael L. Heien, Ann-Sofie Cans, Andrew G Ewing
Analytical Chemistry - 2010-01-01
Analytical approaches to investigate transmitter content and release from single secretory
vesicles

Donna Omiatek, Ann-Sofie Cans, Michael Heien, Andrew G Ewing
Analytical and Bioanalytical Chemistry - 2010-01-01
Probing Exocytosis at Single Cells using
Electrochemistry

Yan Dong, Michael L Heien, Michael E. Kurczy, Andrew G Ewing
Chemical Cytometry: Ultrasensive Analysis of Single Cells (ed C. Lu) - 2010-01-01
Nanotome Cluster Bombardment to Recover Spatial Chemistry After Preparation of Biological Samples for SIMS
Imaging

Michael E. Kurczy, PD Piehowsky, David Willingham, K. Molyneaux, ML Heien, N. Winograd, Andrew G Ewing
JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY - 2010-01-01
Mass spectrometry imaging of mating Tetrahymena show that changes in cell morphology regulate lipid domain
formation

Michael E. Kurczy, PD Piehowsky, CT VanBell, ML Heien, N. Winograd, Andrew G Ewing
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA - 2010-01-01
Only a Fraction of Quantal Content is Released During Exocytosis as Revealed by Electrochemical Cytometry of Secretory
Vesicles

Donna M Omiatek, Yan Dong, ML Heien, Andrew G Ewing
ACS CHEMICAL NEUROSCIENCE - 2010-01-01
Development and Characterization of a Voltammetric Carbon-Fiber Microelectrode pH
Sensor

MA Makos, Donna M Omiatek, Andrew G Ewing, ML Heien
LANGMUIR - 2010-01-01
Using in Vivo Electrochemistry To Study the Physiological Effects of Cocaine and Other Stimulants on the Drosophila melanogaster Dopamine
Transporter

MA Makos, K-A Han, ML Heien, Andrew G Ewing
ACS Chemical Neuroscience - 2010-01-01
Biogenic Amines in Microdissected Brain Regions of Drosophila melanogaster Measured with Mice liar Electrokinetic Capillary Chromatography-Electrochemical
Detection

Nicholas J. Kuklinski, Carina Berglund, Johan Engelbrektsson, Andrew G Ewing
ANALYTICAL CHEMISTRY - 2010-01-01
Determination of salsolinol, norsalsolinol, and twenty-one biogenic amines using micellar electrokinetic capillary chromatography-electrochemical
detection

Nicholas J. Kuklinski, Carina Berglund, Johan Engelbrektsson, Andrew G Ewing
ELECTROPHORESIS - 2010-01-01
Micellar capillary electrophoresis - Electrochemical detection of neurochemicals from
Drosophila

Nicholas J. Kuklinski, Carina Berglund, Andrew G Ewing
JOURNAL OF SEPARATION SCIENCE - 2010-01-01
Time-of-flight secondary ion mass spectrometry imaging of subcellular lipid heterogeneity: Poisson counting and spatial
resolution.

Paul D Piehowski, Angel M Davey, Michael E. Kurczy, Erin D Sheets, Nicholas Winograd, Andrew G Ewing, Michael L Heien
Analytical chemistry - 2009-01-01
Quantitative chemical analysis of single
cells.

Michael L Heien, Andrew G Ewing
Methods in molecular biology book series, Volume 544, Part 2: Micro and Nano Technologies in Bioanalysis (eds Robert S. Foote, James Weifu Lee), - 2009-01-01
Temporal analysis of protozoan lysis in a microfluidic
device.

Michael F Santillo, Michael L Heien, Andrew G Ewing
Lab on a chip - 2009-01-01
Chemical measurements in
Drosophila

Monique A. Makos, Nicholas J. Kuklinski, Michael L. Heien, Andrew G Ewing, Carina Berglund
Trends in Analytical Chemistry - 2009-01-01
In Vivo Electrochemical Measurements of Exogenously Applied Dopamine in Drosophila
melanogaster.

MA Makos, YC Kim, KA Han, ML Heien, Andrew G Ewing
Analytical chemistry - 2009-01-01
Hybrid capillary-microfluidic device for the separation, lysis, and electrochemical detection of
vesicles.

Donna M Omiatek, Michael F Santillo, Michael L Heien, Andrew G Ewing
Analytical chemistry - 2009-01-01
Inhibition of HMGCoA Reductase Reveals An Unexpected Role for Cholesterol During PGC Migration in the
Mouse.

J. Ding, D. Jiang, Michael E. Kurczy, J. Nalepka, B. Dudley, E.I. Merkel, F. D. Porter, Andrew G Ewing, N. Winograd, J. Burgess, K. Molyneaux
BMC developmental biology - 2008-01-01
Which is more important in bioimaging SIMS experiments-The sample preparation or the nature of the
projectile?

Michael E. Kurczy, P. D. Piehowski, S. A. Parry, M. Jiang, G. Chen, Andrew G Ewing, Nicholas Winograd
APPLIED SURFACE SCIENCE - 2008-01-01
Freeze-Etching and Vapor Matrix Deposition for ToF-SIMS Imaging of Single
Cells

Paul D. Piehowski, Michael E. Kurczy, David Willingham, Shawn Parry, Michael L. Heien, Nicholas Winograd, Andrew G Ewing
Langmuir - 2008-01-01
Relative quantification of cellular sections with molecular depth profiling ToF-SIMS
imaging

Michael E. Kurczy, Joseph Kozole, S.A. Parry, Nicholas Winograd, Andrew G Ewing
Applied Surface Science - 2008-01-01
MS/MS Methodology To Improve Subcellular Mapping of Cholesterol Using
TOF-SIMS

Paul D. Piehowski, Anthony J. Carado, Michael E. Kurczy, Sara G. Ostrowski, Michael L. Heien, Nicholas Winograd, Andrew G Ewing
Anal. Chem. - 2008-01-01
Investigating lipid–lipid and lipid–protein interactions in model membranes by
ToF-SIMS

L. Zheng, C.M. McQuaw, Andrew G Ewing
Applied Surface Science - 2008-01-01
The PC12 cell as model for
neurosecretion

R.H.S. Westerink, Andrew G Ewing
Acta Physiologica - 2008-01-01
Amperometric measurements of catecholamine release from single vesicles in MN9D
cells.

Yan Dong, Michael L Heien, Marc M Maxson, Andrew G Ewing
Journal of neurochemistry - 2008-01-01
Spatially and Temporally Resolved Single-Cell Exocytosis Utilizing Individually Addressable Carbon Microelectrode
Arrays

Bo Zhang, Kelly L. Adams, Sarah J. Luber, Daniel J. Eves, Michael Heien, Andrew G Ewing
Anal.Chem. - 2008-01-01
In Vitro Electrochemistry of Biological
Systems

Kelly L. Adams, Maja Puchades, Andrew G Ewing
Annual Reviews of Analytical Chemistry - 2008-01-01
Short-Chain Alcohols Promote Accelerated Membrane Distention in a Dynamic Liposome Model of
Exocytosis

N J Wittenberg, Leiliang Zheng, Nicholas Winograd, Andrew G Ewing
Langmuir - 2008-01-01
Secondary Ion MS Imaging To Relatively Quantify Cholesterol in the Membranes of Individual Cells from Differentially Treated
Populations

Sara G Ostrowski, Michael E. Kurczy, Thomas P Roddy, Nicholas Winograd, Andrew G Ewing
Analytical chemistry - 2007-01-01
Phospholipid mediated plasticity in exocytosis observed in PC12
cells

Yoshiko Uchiyama, M M Maxson, Tsuguo Sawada, Akihiko Nakano, Andrew G Ewing
Brain Research - 2007-01-01
Electrochemistry inside and outside single nerve
cells

D J Eves, Andrew G Ewing
New Frontiers in Ultrasensitive Bioanalysis: Advanced Analytical ChemistryApplications in Nanobiotechnology, Single Molecule Detection, and Single Cell Analysis - 2007-01-01
Localization of Sphingomyelin in Cholesterol Domains by Imaging Mass
Spectrometry

Carolyn M McQuaw, Leiliang Zheng, Andrew G Ewing, Nicholas Winograd
Langmuir - 2007-01-01
Electrochemistry at the cell membrane/solution
interface

N J Wittenberg, M M Maxson, D J Eves, A-S Cans, Andrew G Ewing
Electrochemical Methods for Neouroscience - 2007-01-01
Capillary Electrophoresis for the Analysis of Single Cells: Sampling, Detection and
Applications

Imee G Arcibal, Michael F Santillo, Andrew G Ewing
Handbook of Capillary and Microchop Electrophoresis and Associated Microtechniques - 2007-01-01
High Osmolarity and L-DOPA Augment Release via the Fusion Pore in PC12
Cells

L A Sombers, M M Maxson, N J Wittenberg, Andrew G Ewing
Chemphyschem - 2007-01-01
Multicore Vesicles: Hyperosmolarity and l-DOPA Induce Homotypic Fusion of Dense Core
Vesicles

L A Sombers, M M Maxson, Andrew G Ewing
Cellular and Molecular Neurobiology - 2007-01-01
Flow characterization of a microfluidic device to selectively and reliably apply reagents to a cellular
network

Michael F Santillo, Imee G Arcibal, Andrew G Ewing
Lab on aChip - 2007-01-01
Recent advances in capillary electrophoretic analysis of individual
cells

Imee G Arcibal, Michael F Santillo, Andrew G Ewing
Analytical and Bioanalytical Chemistry - 2007-01-01
Electrochemistry in and at single biological
cells

N J Wittenberg, Andrew G Ewing
Handbook of Electrochemistry - 2007-01-01
Chemical analysis in nanoscale surfactant
networks

Roger Karlsson, A. Karlsson, Andrew G Ewing, P. Dommersnes, J. F. Joanny, Aldo Jesorka, Owe Orwar
Analytical Chemistry - 2006-01-01
The effects of vesicular volume on secretion through the fusion pore in exocytotic release from PC12
cells

L.A. Sombers, H.J. Hanchar, T.L. Colliver, N. Wittenberg, Ann-Sofie Cans, S. Arbault, C. Amatore, Andrew G Ewing
Journal of Neuroscience - 2004-01-01
Measurement of the Dynamics of Exocytosis and Vesicle Retrieval at Cell Populations using a Quartz Crystal
Microbalance

Ann-Sofie Cans, Fredrik Höök, Oleg Shupliakov, Andrew G Ewing, Peter S Eriksson, Lennart Brodin, Owe Orwar
Analytical Chemistry - 2001-01-01