Göran Landberg

PROFESSOR/ CHIEF PHYSICIAN

Department of Laboratory

Medicine

Mail

goran.landberg@gu.se

Fax

+46 31-41 32 90

Visiting address

Gula stråket 8

41345 Göteborg

Postal address

Box 100

40530 Göteborg

Publications

Characterization of cell-free breast cancer patient-derived scaffolds using liquid chromatography-mass spectrometry/mass spectrometry data and RNA sequencing
data

Göran Landberg, Emma Jonasson, Anna Gustafsson, Paul A. Fitzpatrick, Pauline Isakson, Joakim Karlsson, Erik Larsson, Andreas Svanstrom, Svanheidur Rafnsdottir, Emma Persson, Daniel Andersson, J. Rosendahl, S. Petronis, Parmida Ranji, Pernilla Gregersson, Ylva Magnusson, J. Hakansson, Anders Ståhlberg
Data in Brief - 2020-01-01
The mevalonate precursor enzyme HMGCS1 is a novel marker and key mediator of cancer stem cell enrichment in luminal and basal models of breast
cancer

Claire Walsh, Nina Akrap, Elena Garre, Ylva Magnusson, H. Harrison, Daniel Andersson, Emma Jonasson, S. Rafnsdottir, H. Choudhry, F. Buffa, J. Ragoussis, Anders Ståhlberg, A. Harris, Göran Landberg
PLoS ONE - 2020-01-01
Breast cancer stromal clotting activation (Tissue Factor and thrombin): A pre-invasive phenomena that is prognostic in
invasion

H. Shaker, N. J. Bundred, Göran Landberg, S. A. Pritchard, H. Albadry, S. L. Nicholson, L. J. Harries, J. Y. E. Heah, J. Castle, C. C. Kirwan
Cancer Medicine - 2020-01-01
Patient-derived scaffolds uncover breast cancer promoting properties of the
microenvironment

Göran Landberg, Paul A. Fitzpatrick, Pauline Isakson, Emma Jonasson, Joakim Karlsson, E. Larsson, Andreas Svanström, Svanheidur Rafnsdottir, Emma Persson, Anna Gustafsson, Daniel Andersson, J. Rosendahl, S. Petronis, Parmida Ranji, Pernilla Gregersson, Ylva Magnusson, J. Hakansson, Anders Ståhlberg
Biomaterials - 2020-01-01
JAK–STAT signalling controls cancer stem cell properties including chemotherapy resistance in myxoid
liposarcoma

Soheila Dolatabadi, Emma Jonasson, Malin Lindén, Bentolhoda Fereydouni, Karin Bäcksten, Malin Nilsson, Anna Martner, Amin Forootan, Henrik Fagman, Göran Landberg, Pierre Åman, Anders Ståhlberg
International Journal of Cancer - 2019-01-01
Hypoxia-induced secretion stimulates breast cancer stem cell regulatory signalling
pathways

Hanna Jacobsson, H. Harrison, Éamon Hughes, Emma Persson, Sara Rhost, Paul A. Fitzpatrick, Anna Gustafsson, Daniel Andersson, Pernilla Gregersson, Ylva Magnusson, Anders Ståhlberg, Göran Landberg
Molecular Oncology - 2019-01-01
Identification of breast cancer stem cell related genes using functional cellular assays combined with single-cell RNA sequencing in MDA-MB-231
cells

Emma Jonasson, Salim Ghannoum, Emma Persson, Joakim Karlsson, Thomas Kroneis, Erik Larsson, Göran Landberg, Anders Ståhlberg
Frontiers in Genetics - 2019-01-01
Sortilin inhibition limits secretion-induced progranulin-dependent breast cancer progression and cancer stem cell
expansion

Sara Rhost, Éamon Hughes, H. Harrison, Svanheidur Rafnsdottir, Hanna Jacobsson, Pernilla Gregersson, Ylva Magnusson, Paul A. Fitzpatrick, Daniel Andersson, Karoline Berger, Anders Ståhlberg, Göran Landberg
Breast cancer research : BCR - 2018-01-01
Identification of inhibitors regulating cell proliferation and FUS-DDIT3 expression in myxoid liposarcoma using combined DNA, mRNA, and protein
analyses.

David Svec, Soheila Dolatabadi, Christer Thomsen, Nicole Cordes, Mark Shannon, Paul A. Fitzpatrick, Göran Landberg, Pierre Åman, Anders Ståhlberg
Laboratory investigation; a journal of technical methods and pathology - 2018-01-01
Cell Cycle and Cell Size Dependent Gene Expression Reveals Distinct Subpopulations at Single-Cell
Level

Soheila Dolatabadi, J. Candia, Nina Akrap, Christoffer Vannas, Tajana Tesan Tomic, W. Losert, Göran Landberg, Pierre Åman, Anders Ståhlberg
Frontiers in Genetics - 2017-01-01
Pterocarpans and isoflavones from the root bark of Millettia micans and of Millettia
dura

M. Marco, Tsegaye Deyou, Amra Gruhonjic, J. Holleran, S. Duffy, M. Heydenreich, Paul A. Fitzpatrick, Göran Landberg, A. Koch, S. Derese, J. Pelletier, V. M. Avery, Mate Erdelyi, A. Yenesew
Phytochemistry Letters - 2017-01-01
Robotic Mammosphere Assay for High-Throughput Screening in Triple-Negative Breast
Cancer

Paul A. Fitzpatrick, Nina Akrap, Elin Söderberg, H. Harrison, G. J. Thomson, Göran Landberg
Slas Discovery - 2017-01-01
High expression of stromal PDGFR beta is associated with reduced benefit of tamoxifen in breast
cancer

J. Paulsson, L. Ryden, C. Strell, O. Frings, N. P. Tobin, T. Fornander, J. Bergh, Göran Landberg, O. Stal, A. Ostman
Journal of Pathology Clinical Research - 2017-01-01
Tissue Factor promotes breast cancer stem cell activity in
vitro

H. Shaker, H. Harrison, R. Clarke, Göran Landberg, N. J. Bundred, H. H. Versteeg, C. C. Kirwan
Oncotarget - 2017-01-01
Cellular organization and molecular differentiation model of breast cancer-associated
fibroblasts

Susann Busch, Daniel Andersson, Eva Bom, Claire Walsh, Anders Ståhlberg, Göran Landberg
Molecular Cancer - 2017-01-01
Lipid Heterogeneity Resulting from Fatty Acid Processing in the Human Breast Cancer Microenvironment Identified by GCIB-ToF-SIMS
Imaging

Tina B. Angerer, Ylva Magnusson, Göran Landberg, John S. Fletcher
Analytical Chemistry - 2016-01-01
Pterocarpans and isoflavones from the roots of Millettia micans and of Millettia
dura

Marco Makungu, Tsegaye Deyou, Amra Gruhonjic, John P. Holleran, Sandra Duffy, Matthias Heydenreich, Paul A. Fitzpatrick, Göran Landberg, Andreas Koch, Solomon Derese, Jerry Pelletier, Vicky M. Avery, Mate Erdelyi, Abiy Yenesew
Advances in Drug Discovery and Development - 2016-01-01
Phytoconstituents with Radical Scavenging and Cytotoxic Activities from Diospyros
shimbaensis

Per Aronsson, Joan J. E. Munissi, Amra Gruhonjic, Paul A. Fitzpatrick, Göran Landberg, Stephen S. Nyandoro, Mate Erdelyi
Diseases - 2016-01-01
Naphthalene Derivatives from the Roots of Pentas parvifolia and Pentas
bussei

Negera Abdissa, F. Pan, Amra Gruhonjic, Jürgen Gräfenstein, Paul A. Fitzpatrick, Göran Landberg, K. Rissanen, A. Yenesew, Mate Erdelyi
Journal of natural products - 2016-01-01
An Endothelial Gene Signature Score Predicts Poor Outcome in Patients with Endocrine-Treated, Low Genomic Grade Breast
Tumors

N. P. Tobin, K. Wennmalm, L. S. Lindstrom, T. Foukakis, L. Q. He, G. Genove, A. Ostman, Göran Landberg, Christer Betsholtz, J. Bergh
Clinical Cancer Research - 2016-01-01
Identification of Distinct Breast Cancer Stem Cell Populations Based on Single-Cell Analyses of Functionally Enriched Stem and Progenitor
Pools

Nina Akrap, Daniel Andersson, Eva Bom, Pernilla Gregersson, Anders Ståhlberg, Göran Landberg
Stem Cell Reports - 2016-01-01
Selenium Accumulating Leafy Vegetables Are a Potential Source of Functional
Foods

P. E. Mabeyo, M. L. K. Manoko, Amra Gruhonjic, Paul A. Fitzpatrick, Göran Landberg, Mate Erdelyi, Stephen S. Nyandoro
International Journal of Food Science - 2015-01-01
Rotenoids, Flavonoids, and Chalcones from the Root Bark of Millettia
usaramensis

Tsegaye Deyou, Ivan Gumula, F. F. Pang, Amra Gruhonjic, M. Mumo, J. Holleran, S. Duffy, Paul A. Fitzpatrick, M. Heydenreich, Göran Landberg, S. Derese, V. Avery, K. Rissanen, Mate Erdelyi, A. Yenesew
Journal of Natural Products - 2015-01-01
N-Cinnamoyltetraketide Derivatives from the Leaves of Toussaintia
orientalis

Stephen S. Nyandoro, J. Ndanu, Joan J. E. Munissi, Amra Gruhonjic, Paul A. Fitzpatrick, Göran Landberg, You Lu, B. Wang, F. Pan, K. Rissanen, Mate Erdelyi
Journal of natural products - 2015-01-01
Early diagnostic value of Bcl-3 localization in colorectal
cancer

K. Saamarthy, Sofie Björner, M. Johansson, Göran Landberg, R. Massoumi, K. Jirstrom, K. C. Masoumi
Bmc Cancer - 2015-01-01
Properties of targeted preamplification in DNA and cDNA
quantification

Daniel Andersson, Nina Akrap, David Svec, T. E. Godfrey, M. Kubista, Göran Landberg, Anders Ståhlberg
Expert Review of Molecular Diagnostics - 2015-01-01
Monocytes and macrophages, implications for breast cancer migration and stem cell-like activity and
treatment

R. Ward, A. H. Sims, A. Lee, C. Lo, L. Wynne, H. Yusuf, H. Gregson, M. p Lisanti, F. Sotgia, Göran Landberg, R. Lamb
OncoTarget - 2015-01-01
Loss of TGF beta Receptor Type 2 Expression Impairs Estrogen Response and Confers Tamoxifen
Resistance

Susann Busch, A. H. Sims, O. Stal, M. Ferno, Göran Landberg
Cancer Research - 2015-01-01
TGF-beta receptor type-2 expression in cancer-associated fibroblasts regulates breast cancer cell growth and survival and is a prognostic marker in pre-menopausal breast
cancer

Susann Busch, A. Acar, Yvonne Magnusson, Pernilla Gregersson, L. Rydén, Göran Landberg
Oncogene - 2015-01-01
Focal Adhesion Kinase and Wnt Signaling Regulate Human Ductal Carcinoma In Situ Stem Cell Activity and Response to
Radiotherapy

K. E. Williams, N. J. Bundred, Göran Landberg, R. B. Clarke, G. Farnie
Stem Cells - 2015-01-01
Cytotoxic Quinones from the roots of Aloe
dawei

Negera Abdissa, Martha Induli, Paul A. Fitzpatrick, John Patrick Alao, Per Sunnerhagen, Göran Landberg, Abiy Yenesew, Mate Erdelyi
Molecules - 2014-01-01
Co-ordination of cell cycle, migration and stem cell-like activity in breast
cancer

R. Lamb, M. P. Lisanti, R. B. Clarke, Göran Landberg
Oncotarget - 2014-01-01
17 beta-estradiol regulates giant vesicle formation via estrogen receptor-alpha in human breast cancer
cells

P. K. Wright, S. B. Jones, N. Ardern, R. Ward, R. B. Clarke, F. Sotgia, M. P. Lisanti, Göran Landberg, R. Lamb
Oncotarget - 2014-01-01
Epithelial and Stromal MicroRNA Signatures of Columnar Cell Hyperplasia Linking Let-7c to Precancerous and Cancerous Breast Cancer Cell
Proliferation

Sofie Björner, Paul A. Fitzpatrick, Y. Y. Li, C. Allred, A. Howell, A. Ringberg, H. Olsson, C. J. Miller, H. Axelson, Göran Landberg
Plos One - 2014-01-01
Constituents of the Roots and Leaves of Ekebergia capensis and Their Potential Antiplasmodial and Cytotoxic
Activities

Beatrice N. Irungu, Jennifer A. Orwa, Amra Gruhonjic, Paul A. Fitzpatrick, Göran Landberg, Francis Kimani, Jacob Midiwo, Mate Erdelyi, Abiy Yenesew
Molecules - 2014-01-01
Decreased expression of Yes-associated protein is associated with outcome in the luminal A breast cancer subgroup and with an impaired tamoxifen
response

S. Lehn, N. P. Tobin, A. H. Sims, O. Stal, K. Jirstrom, H. Axelson, Göran Landberg
Bmc Cancer - 2014-01-01
Targeting CXCR1/2 Significantly Reduces Breast Cancer Stem Cell Activity and Increases the Efficacy of Inhibiting HER2 via HER2-dependent and -independent
Mechanisms.

Jagdeep K Singh, Gillian Farnie, Nigel J Bundred, Bruno M Simoes, Amrita Shergill, Göran Landberg, Sacha Howell, Robert B Clarke
Clinical cancer research : an official journal of the American Association for Cancer Research - 2013-01-01
Oestrogen increases the activity of oestrogen receptor negative breast cancer stem cells through paracrine EGFR and Notch
signalling

H. Harrison, B. M. Simões, L. Rogerson, S. J. Howell, Göran Landberg, R. B. Clarke
Breast Cancer Research - 2013-01-01
Cell cycle regulators cyclin D1 and CDK4/6 have estrogen receptor-dependent divergent functions in breast cancer migration and stem cell-like
activity

R. Lamb, S. Lehn, L. Rogerson, R. B. Clarke, Göran Landberg
Cell Cycle - 2013-01-01
Contrasting hypoxic effects on breast cancer stem cell hierarchy is dependent on ERα
status.

Hannah Harrison, Lynsey Rogerson, Hannah J Gregson, Keith R Brennan, Robert B Clarke, Göran Landberg
Cancer research - 2013-01-01
Automated image analysis of cyclin D1 protein expression in invasive lobular breast carcinoma provides independent prognostic
information.

Nicholas P Tobin, Katja L Lundgren, Catherine Conway, Lola Anagnostaki, Sean Costello, Göran Landberg
Human pathology - 2012-01-01
Med1 plays a critical role in the development of tamoxifen
resistance.

Arumugam Nagalingam, Mourad Tighiouart, Lisa Ryden, Leena Joseph, Göran Landberg, Neeraj K Saxena, Dipali Sharma
Carcinogenesis - 2012-01-01
Genetic predisposition, parity, age at first childbirth and risk for breast
cancer.

Salma Butt, Sophia Harlid, Signe Borgquist, Malin Ivarsson, Göran Landberg, Joakim Dillner, Joyce Carlson, Jonas Manjer
BMC research notes - 2012-01-01
Downregulation of miR-92a is associated with aggressive breast cancer features and increased tumour macrophage
infiltration.

Sofie Nilsson, Christina Möller, Karin Jirström, Alexander Lee, Susann Busch, Rebecca Lamb, Göran Landberg
PloS one - 2012-01-01
Low ERK Phosphorylation in Cancer-Associated Fibroblasts Is Associated with Tamoxifen Resistance in Pre-Menopausal Breast
Cancer

S. Busch, L. Ryden, O. Stal, K. Jirstrom, Göran Landberg
Plos One - 2012-01-01
Effects of cyclin D-1 gene amplification and protein expression on time to recurrence in postmenopausal breast cancer patients treated with anastrozole or tamoxifen: a TransATAC
study

K. Lundgren, M. Brown, S. Pineda, J. Cuzick, J. Salter, L. Zabaglo, A. Howell, M. Dowsett, Göran Landberg
Breast Cancer Research - 2012-01-01
Tumour-related factors and prognosis in breast cancer detected by
screening.

A Olsson, S Borgquist, S Butt, S Zackrisson, Göran Landberg, J Manjer
The British journal of surgery - 2012-01-01
Stromal expression of β-arrestin-1 predicts clinical outcome and tamoxifen response in breast
cancer.

Katja Lundgren, Nicholas P Tobin, Sophie Lehn, Olle Stål, Lisa Rydén, Karin Jirström, Göran Landberg
The Journal of molecular diagnostics : JMD - 2011-01-01
The cocaine- and amphetamine-regulated transcript mediates ligand-independent activation of ERα, and is an independent prognostic factor in node-negative breast
cancer.

D J Brennan, D P O'Connor, H Laursen, S F McGee, S McCarthy, R Zagozdzon, E Rexhepaj, A C Culhane, F M Martin, M J Duffy, Göran Landberg, L Ryden, S M Hewitt, M J Kuhar, R Bernards, R C Millikan, J P Crown, K Jirström, W M Gallagher
Oncogene - 2011-01-01
Cyclin D1, Id1 and EMT in breast
cancer.

Nicholas P Tobin, Andrew H Sims, Katja L Lundgren, Sophie Lehn, Göran Landberg
BMC cancer - 2011-01-01
FoxO3A promotes metabolic adaptation to hypoxia by antagonizing Myc
function.

Kim Steen Jensen, Tina Binderup, Klaus Thorleif Jensen, Ib Therkelsen, Rehannah Borup, Elise Nilsson, Hinke Multhaupt, Caroline Bouchard, Bjørn Quistorff, Andreas Kjær, Göran Landberg, Peter Staller
The EMBO journal - 2011-01-01
Hypoxic induction of vascular endothelial growth factor regulates murine hematopoietic stem cell function in the low-oxygenic
niche.

Matilda Rehn, André Olsson, Kristian Reckzeh, Eva Diffner, Peter Carmeliet, Göran Landberg, Jörg Cammenga
Blood - 2011-01-01
The HOXB7 protein renders breast cancer cells resistant to tamoxifen through activation of the EGFR
pathway.

Kideok Jin, Xiangjun Kong, Tariq Shah, Marie-France Penet, Flonne Wildes, Dennis C Sgroi, Xiao-Jun Ma, Yi Huang, Anne Kallioniemi, Göran Landberg, Ivan Bieche, Xinyan Wu, Peter E Lobie, Nancy E Davidson, Zaver M Bhujwalla, Tao Zhu, Saraswati Sukumar
Proceedings of the National Academy of Sciences of the United States of America - 2011-01-01
Risk of recurrence following delayed large flap reconstruction after mastectomy for breast
cancer.

A E Isern, J Manjer, J Malina, N Loman, T Mårtensson, A Bofin, A I Hagen, I Tengrup, Göran Landberg, A Ringberg
The British journal of surgery - 2011-01-01
A non-functional retinoblastoma tumor suppressor (RB) pathway in premenopausal breast cancer is associated with resistance to
tamoxifen.

Sophie Lehn, Mårten Fernö, Karin Jirström, Lisa Rydén, Göran Landberg
Cell cycle - 2011-01-01
Isolation and characterization of progenitor-like cells from human renal proximal
tubules.

David Lindgren, Anna-Karin Boström, Kristina Nilsson, Jennifer Hansson, Jonas Sjölund, Christina Möller, Karin Jirström, Elise Nilsson, Göran Landberg, Håkan Axelson, Martin E Johansson
The American journal of pathology - 2011-01-01
PKA-induced phosphorylation of ERα at serine 305 and high PAK1 levels is associated with sensitivity to tamoxifen in ER-positive breast
cancer.

Marleen Kok, Wilbert Zwart, Caroline Holm, Renske Fles, Michael Hauptmann, Laura J Van't Veer, Lodewyk F A Wessels, Jacques Neefjes, Olle Stål, Sabine C Linn, Göran Landberg, Rob Michalides
Breast cancer research and treatment - 2011-01-01
A practical guide to constructing and using tissue
microarrays.

Ian Chandler, Richard Houlston, Göran Landberg
Methods in molecular biology - 2011-01-01
Food sources of fat and sex hormone receptor status of invasive breast tumors in women of the Malmö Diet and Cancer
cohort.

Elisabet Wirfält, Cairu Li, Jonas Manjer, Ulrika Ericson, Emily Sonestedt, Signe Borgquist, Göran Landberg, Håkan Olsson, Bo Gullberg
Nutrition and cancer - 2011-01-01
Genomic alterations in histopathologically normal breast tissue from BRCA1 mutation carriers may be caused by BRCA1
haploinsufficiency.

Karin Rennstam, Anita Ringberg, Heather E Cunliffe, Håkan Olsson, Göran Landberg, Ingrid Hedenfalk
Genes, chromosomes & cancer - 2010-01-01
Cyclooxygenase-2 inhibition does not improve the reduction in ductal carcinoma in situ proliferation with aromatase inhibitor therapy: results of the ERISAC randomized placebo-controlled
trial.

Nigel J Bundred, Angela Cramer, Julie Morris, Lorna Renshaw, Kwok-Leung Cheung, Pamela Flint, Rachael Johnson, Oliver Young, Göran Landberg, Sue Grassby, Lorraine Turner, Andrew Baildam, Lester Barr, J Michael Dixon
Clinical cancer research : an official journal of the American Association for Cancer Research - 2010-01-01
PKCalpha expression is a marker for breast cancer
aggressiveness.

Gry Kalstad Lønne, Louise Cornmark, Iris Omanovic Zahirovic, Göran Landberg, Karin Jirström, Christer Larsson
Molecular cancer - 2010-01-01
Acetylation-dependent oncogenic activity of metastasis-associated protein 1
co-regulator.

Kazufumi Ohshiro, Suresh K Rayala, Caroline Wigerup, Suresh B Pakala, Reddy S Divijendra Natha, Anupama E Gururaj, Poonam R Molli, Sofie Svensson Månsson, Ali Ramezani, Robert G Hawley, Göran Landberg, Norman H Lee, Rakesh Kumar
EMBO reports - 2010-01-01
Validation of cytoplasmic-to-nuclear ratio of survivin as an indicator of improved prognosis in breast
cancer.

Elton Rexhepaj, Karin Jirstrom, Darran P O'Connor, Sallyann L O'Brien, Göran Landberg, Michael J Duffy, Donal J Brennan, William M Gallagher
BMC cancer - 2010-01-01
Down-regulation of the oncogene cyclin D1 increases migratory capacity in breast cancer and is linked to unfavorable prognostic
features.

Sophie Lehn, Nicholas P Tobin, Pontus Berglund, Kristina Nilsson, Andrew H Sims, Karin Jirström, Pirkko Härkönen, Rebecca Lamb, Göran Landberg
The American journal of pathology - 2010-01-01
p27Kip1 is a predictive factor for tamoxifen treatment response but not a prognostic marker in premenopausal breast cancer
patients.

Maria Stendahl, Sofie Nilsson, Caroline Wigerup, Karin Jirström, Per Ebbe Jönsson, Olle Stål, Göran Landberg
International journal of cancer. Journal international du cancer - 2010-01-01
Estrogen receptor-alpha phosphorylation at serine-118 and tamoxifen response in breast
cancer.

Marleen Kok, Caroline Holm-Wigerup, Michael Hauptmann, Rob Michalides, Olle Stål, Sabine Linn, Göran Landberg
Journal of the National Cancer Institute - 2009-01-01