Jenny Nyström
Head of Department
Institute of Neuroscience andAbout Jenny Nyström
Research group
Renal function and glomerular kidney disease
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Glomerular Endothelial Cell-Derived miR-200c Impairs Glomerular Homeostasis by Targeting Podocyte
VEGF-A
R. Ursu, N. Sopel, A. Ohs, R. Tati, L. Buvall, Jenny Nyström, M. Schiffer, J. Muller-Deile
International Journal of Molecular Sciences - 2022 -
Bilirubin levels and kidney function decline: An analysis of clinical trial and real world
data
Y. Aoki, C. S. Cabrera, M. Ouwens, K. Bamberg, Jenny Nyström, I. Raz, B. M. Scirica, B. Hamren, P. J. Greasley, D. Rekic
Plos One - 2022 -
The role of dendrin in IgA
nephropathy
A. Levin, A. Schwarz, J. Hulkko, L. Q. He, Y. Sun, P. Barany, A. Bruchfeld, M. Herthelius, L. Wennberg, Kerstin Ebefors, J. Patrakka, C. Betsholtz, Jenny Nyström, Johan Mölne, K. Hultenby, A. Witasp, A. Wernerson
Nephrology Dialysis Transplantation - 2022 -
Modified lipid metabolism and cytosolic phospholipase A2 activation in mesangial cells under pro-inflammatory
conditions
Roberto Boi, Kerstin Ebefors, Marcus Henricsson, Jan Borén, Jenny Nyström
Scientific Reports - 2022 -
The Glomerulus According to the
Mesangium
Kerstin Ebefors, Lovisa Bergwall, Jenny Nyström
Frontiers in Medicine - 2022 -
The Glomerular Endothelium Restricts Albumin
Filtration
B. J. Ballermann, Jenny Nyström, Börje Haraldsson
Frontiers in Medicine - 2021 -
Mesangioproliferative Kidney Diseases and Platelet-Derived Growth Factor-Mediated AXL
Phosphorylation
Q. Bian, J. C. Anderson, X. W. Zhang, Z. Q. Huang, Kerstin Ebefors, Jenny Nyström, S. Hall, L. Novak, B. A. Julian, C. D. Willey, J. Novak
Kidney Medicine - 2021 -
Proteoglycans contribute to the functional integrity of the glomerular endothelial cell surface layer and are regulated in diabetic kidney
disease
Alina Khramova, Roberto Boi, Vincent Fridén, Anna Björnson Granqvist, Ulf Nilsson, O. Tenstad, E. Oveland, Börje Haraldsson, Kerstin Ebefors, Jenny Nyström
Scientific Reports - 2021 -
Depletion of protein kinase STK25 ameliorates renal lipotoxicity and protects against diabetic kidney
disease.
Emmelie Cansby, Mara Caputo, Lei Gao, Nagaraj M. Kulkarni, Annika Nerstedt, Marcus Ståhlman, Jan Borén, Rando Porosk, Ursel Soomets, Matteo Pedrelli, Paolo Parini, Hanns-Ulrich Marschall, Jenny Nyström, Brian W Howell, Margit Mahlapuu
JCI insight - 2020 -
Novel insights into the disease transcriptome of human diabetic glomeruli and
tubulointerstitium
A. Levin, A. Reznichenko, A. Witasp, Peidi Liu, P. J. Greasley, A. Sorrentino, T. Blondal, S. Zambrano, J. Nordstrom, A. Bruchfeld, P. Barany, Kerstin Ebefors, F. Erlandsson, J. Patrakka, P. Stenvinkel, Jenny Nyström, A. Wernerson
Nephrology Dialysis Transplantation - 2020 -
Localization and Regulation of Polymeric Ig Receptor in Healthy and Diseased Human
Kidney
K. M. Krawczyk, H. Nilsson, Jenny Nyström, D. Lindgren, K. Leandersson, K. Sward, M. E. Johansson
American Journal of Pathology - 2019 -
Mice exposed to maternal androgen excess and diet-induced obesity have altered phosphorylation of catechol-O-methyltransferase in the placenta and fetal
liver
R. Fornes, M. Manti, X. J. Qi, Egor Vorontsov, Carina Sihlbom, Jenny Nyström, Elisabeth Jerlhag, M. Maliqueo, A. L. Hirschberg, M. Carlstrom, Anna Benrick, E. Stener-Victorin
International Journal of Obesity - 2019 -
GPRC5b Modulates Inflammatory Response in Glomerular Diseases via NF-kappa B
Pathway
S. Zambrano, K. Moller-Hackbarth, X. D. Li, P. Q. Rodriguez, E. Charrin, A. Schwarz, Jenny Nyström, A. O. Wernerson, M. Lal, J. Patrakka
Journal of the American Society of Nephrology - 2019 -
Identification of cell and disease specific microRNAs in glomerular
pathologies
J. Muller-Deile, J. Dannenberg, Peidi Liu, J. Lorenzen, Jenny Nyström, T. Thum, M. Schiffer
Journal of Cellular and Molecular Medicine - 2019 -
Novel ELISA for thrombospondin type 1 domain-containing 7A autoantibodies in membranous
nephropathy
C. Zaghrini, B. Seitz-Polski, J. Justino, G. Dolla, C. Payre, N. Jourde-Chiche, A. E. Van de Logt, C. Booth, E. Rigby, Jennie Lönnbro-Widgren, Jenny Nyström, C. Mariat, Z. Cui, J. F. M. Wetzels, G. Ghiggeri, L. H. Beck, P. Ronco, H. Debiec, G. Lambeau
Kidney International - 2019 -
A CRISP(e)R view on kidney organoids allows generation of an induced pluripotent stem cell-derived kidney model for drug
discovery
C. Borestrom, A. Jonebring, J. Guo, H. Palmgren, L. Cederblad, A. Forslow, A. Svensson, M. Soderberg, A. Reznichenko, Jenny Nyström, J. Patrakka, R. Hicks, M. Maresca, B. Valastro, A. Collen
Kidney International - 2018 -
Amplification of the Melanocortin-1 Receptor in Nephrotic Syndrome Identifies a Target for Podocyte Cytoskeleton
Stabilization
Lovisa Bergwall, Hanna Wallentin, Johannes Elvin, Peidi Liu, Roberto Boi, Carina Sihlbom, K. Hayes, D. Wright, Börje Haraldsson, Jenny Nyström, Lisa Buvall
Scientific Reports - 2018 -
Pharmacokinetic Properties of the Nephrotoxin Orellanine in
Rats
Deman Hadi Najar, Börje Haraldsson, Annika Thorsell, Carina Sihlbom, Jenny Nyström, Kerstin Ebefors
Toxins - 2018 -
Overexpression of preeclampsia induced microRNA-26a-5p leads to proteinuria in
zebrafish
J. Muller-Deile, P. Schroder, L. Beverly-Staggs, R. Hiss, J. Fiedler, Jenny Nyström, T. Thum, H. Haller, M. Schiffer
Scientific Reports - 2018 -
Orellanine specifically targets renal clear cell
carcinoma.
Lisa Buvall, Heidi Hedman, Alina Khramova, Deman Hadi Najar, Lovisa Bergwall, Kerstin Ebefors, Carina Sihlbom, Sven Lundstam, Anders Herrmann, Hanna Wallentin, Emelie Roos, Ulf Nilsson, Martin Johansson, Jan Törnell, Börje Haraldsson, Jenny Nyström
Oncotarget - 2017 -
Transcriptomic and Proteomic Profiling Provides Insight into Mesangial Cell Function in IgA
Nephropathy
Peidi Liu, Emelie Lassén, V. Nair, C. C. Berthier, M. Suguro, Carina Sihlbom, M. Kretzler, C. Betsholtz, Börje Haraldsson, W. J. Ju, Kerstin Ebefors, Jenny Nyström
Journal of the American Society of Nephrology - 2017 -
Podocytes regulate the glomerular basement membrane protein nephronectin by means of miR-378a-3p in glomerular
diseases
J. Muller-Deile, J. Dannenberg, P. Schroder, M. H. Lin, J. H. Miner, R. J. Chen, J. H. Brasen, T. Thum, Jenny Nyström, L. B. Staggs, H. Haller, J. Fiedler, J. M. Lorenzen, M. Schiffer
Kidney International - 2017 -
The effect of androgen excess on maternal metabolism, placental function and fetal growth in obese
dams
R. Fornes, M. Maliqueo, Min Hu, Laila Hadi, J. M. Jimenez-Andrade, Kerstin Ebefors, Jenny Nyström, F. Labrie, T. Jansson, Anna Benrick, E. Stener-Victorin
Scientific Reports - 2017 -
New insights into crosstalk in the
kidney
Kerstin Ebefors, Jenny Nyström
Current Opinion in Nephrology and Hypertension - 2017 -
Overexpression of TGF-beta Inducible microRNA-143 in Zebrafish Leads to Impairment of the Glomerular Filtration Barrier by Targeting
Proteoglycans
J. Muller-Deile, F. Gellrich, H. Schenk, P. Schroder, Jenny Nyström, J. Lorenzen, H. Haller, M. Schiffer
Cellular Physiology and Biochemistry - 2016 -
Treatment pattern in patients with idiopathic membranous nephropathy-practices in Sweden at the start of the
millennium
Jennie Lönnbro-Widgren, Johan Mölne, Börje Haraldsson, Jenny Nyström
Clinical Kidney Journal - 2016 -
Mesangial cells from patients with IgA nephropathy have increased susceptibility to galactose-deficient
IgA1
Kerstin Ebefors, Peidi Liu, Emelie Lassén, Johannes Elvin, Emma Candemark, Kristina Levan, Börje Haraldsson, Jenny Nyström
Bmc Nephrology - 2016 -
Melanocortin 1 Receptor Agonist Protects Podocytes Through Catalase and RhoA
Activation.
Johannes Elvin, Lisa Buvall, Annika Lindskog Jonsson, Anna Björnson Granqvist, Emelie Lassén, Lovisa Bergwall, Jenny Nyström, Börje Haraldsson
American journal of physiology. Renal physiology - 2016 -
Glomerular IgG subclasses in idiopathic and malignancy-associated membranous
nephropathy
Jennie Lönnbro-Widgren, Kerstin Ebefors, Johan Mölne, Jenny Nyström, Börje Haraldsson
Clinical Kidney Journal - 2015 -
Bestrophin-3 is differently expressed in normal and injured mouse glomerular
podocytes.
Veronika Golubinskaya, Johannes Elvin, Kerstin Ebefors, Helena Gustafsson, Carina Mallard, Jenny Nyström, Holger Nilsson
Acta physiologica (Oxford, England) - 2015 -
Rapid Increase of Interleukin-10 Plasma Levels After Combined Auxiliary Liver-Kidney Transplantation in Presensitized
Patients
Madeleine Ingelsten, Karin Gustafsson, Michael Olausson, Börje Haraldsson, Alex Karlsson-Parra, Jenny Nyström
Transplantation - 2014 -
Effects of Melanocortin 1 Receptor Agonists in Experimental
Nephropathies
Annika Lindskog Jonsson, Anna Granqvist, Johannes Elvin, M. E. Johansson, Börje Haraldsson, Jenny Nyström
Plos One - 2014 -
The glomerular endothelium: new insights on function and
structure.
Börje Haraldsson, Jenny Nyström
Current opinion in nephrology and hypertension - 2012 -
Indoleamine 2,3-dioxygenase Expression and Functional Activity in Dendritic Cells Exposed to Cholera
Toxin
Lucija Slavica, Merja Nurkkala Karlsson, Tanya (De L.) Karlson, Madeleine Ingelsten, Jenny Nyström, Kristina Eriksson
Scandinavian Journal of Immunology - 2012 -
Role of glomerular proteoglycans in IgA
nephropathy
Kerstin Ebefors, Anna Björnson Granqvist, Madeleine Ingelsten, Johan Mölne, Börje Haraldsson, Jenny Nyström
PLoS ONE - 2011 -
The glomerular endothelial cell coat is essential for glomerular
filtration
Vincent Fridén, E. Oveland, O. Tenstad, Kerstin Ebefors, Jenny Nyström, Ulf Nilsson, Börje Haraldsson
Kidney international - 2011 -
Postischemic Inflammatory Response in an Auxiliary Liver Graft Predicts Renal Graft Outcome in Sensitized
Patients.
Madeleine Ingelsten, Alex Karlsson-Parra, Anna Björnson Granqvist, Johan Mölne, Michael Olausson, Börje Haraldsson, Jenny Nyström
Transplantation - 2011 -
Melanocortin 1 receptor agonists reduce
proteinuria.
Annika Lindskog, Kerstin Ebefors, Martin E Johansson, Bergur V. Stefánsson, Anna Björnson Granqvist, margret arnadottir, Anna-Lena Berg, Jenny Nyström, Börje Haraldsson
Journal of the American Society of Nephrology : JASN - 2010 -
Impaired glomerular and tubular antioxidative defense mechanisms in nephrotic
syndrome.
Anna Björnson Granqvist, Ulf Nilsson, Kerstin Ebefors, Börje Haraldsson, Jenny Nyström
American journal of physiology. Renal physiology - 2010 -
Is Indoleamine 2,3-Dioxygenase Important for Graft Acceptance in Highly Sensitized Patients After Combined Auxiliary Liver-Kidney
Transplantation?
Madeleine Ingelsten, Karin Gustafsson, Mihai Oltean, Alex Karlsson-Parra, Michael Olausson, Börje Haraldsson, Jenny Nyström
Transplantation - 2009 -
The role of IL-10 in the liver tolerance
effect
Madeleine Ingelsten, Karin Gustafsson, Michael Olausson, Börje Haraldsson, Jenny Nyström, Alex Karlsson-Parra
World congress of Nephrology, Milan 2009 - 2009 -
Liver-derived IL-10 as a potential inhibitor of a TH1-deviating crosstalk between donor DC and recipient NK cells during combined liver-kidney
transplantation
Madeleine Ingelsten, Karin Gustafsson, Michael Olausson, Börje Haraldsson, Jenny Nyström, Alex Karlsson-Parra
The Transplantation society XI Basic science symposium, European society for organ transplantation I Basic science meeting, Brussels 2009. - 2009 -
Mechanisms behind the protective role of the liver in sensitized
patients
Madeleine Ingelsten, Karin Gustafsson, Mihai Oltean, Michael Olausson, Börje Haraldsson, Alex Karlsson-Parra, Jenny Nyström
The transplantation Society, new Key Opinion Leader Meeting Gothenburg 2009 - 2009 -
NC-001 - new potential therapy in metastatic renal cell
carcinoma
Heidi Hedman, Lisa Buvall, Ulf Nilsson, Jenny Nyström, Börje Haraldsson
ASN Renal Week 2009, San Diego, USA 28 Oct - 3 Nov 2009 - 2009 -
a-melanocyte stimulating hormone normalizes puromycin-induced upregulation of melanocortin receptor type 1 in cultured
podocytes
Annika Lindskog, Heidi Hedman, Börje Haraldsson, Jenny Nyström
World Congress of Nephrology, May 22-26, 2009 - Milan, Italy - 2009 -
A human glomerular SAGE transcriptome
database
Jenny Nyström, W. Fierlbeck, Anna Granqvist, S. C. Kulak, B. J. Ballermann
BMC Nephrol - 2009 -
CRIM1 is localized to the podocyte filtration slit diaphragm of the adult human
kidney
Jenny Nyström, K. Hultenby, S. Ek, J. Sjolund, H. Axelson, K. Jirstrom, M. A. Saleem, K. Nilsson, Martin Johansson
Nephrol Dial Transplant - 2009 -
The fungal nephrotoxin orellanine simultaneously increases oxidative stress and down-regulates cellular
defenses
Ulf Nilsson, Jenny Nyström, Lisa Buvall, Kerstin Ebefors, Anna Granqvist, Johan Holmdahl, Börje Haraldsson
Free Radical Biology and Medicine - 2008 -
Properties of the Glomerular Barrier and Mechanisms of
Proteinuria
Börje Haraldsson, Jenny Nyström, W M. Deen
Physiological Reviews - 2008 -
Recruitment and activation of natural killer cells in vitro by a human dendritic cell
vaccine
Karin Gustafsson, Madeleine Ingelsten, Linda Bergqvist, Jenny Nyström, Bengt A. Andersson, Alex Karlsson-Parra
Cancer Research - 2008 -
Mild renal ischemia-reperfusion reduces charge and size selectivity of the glomerular
barrier
Maria Andersson, Ulf Nilsson, Clara Hjalmarsson, Börje Haraldsson, Jenny Nyström
American Journal of Physiology Renal Physiology - 2007 -
Functional and molecular alterations of the glomerular barrier in long-term diabetes in
mice
Marie Jeansson, Anna Granqvist, Jenny Nyström, Börje Haraldsson
Diabetologia - 2006 -
Podocyte proteoglycan synthesis is involved in the development of nephrotic
syndrome
Anna Granqvist, Kerstin Ebefors, M. A. Saleem, P. W. Mathieson, Börje Haraldsson, Jenny Nyström
Am J Physiol Renal Physiol - 2006 -
Primary human glomerular endothelial cells produce proteoglycans, and puromycin affects their posttranslational
modification
Anna Granqvist, Jonatan Moses, A. Ingemansson, Börje Haraldsson, Jenny Nyström
Am J Physiol Renal Physiol - 2005 -
A SAGE-based Comparison between Glomerular and Aortic Endothelial
Cells
G Sengoelge, W Luo, W Fierlbeck, D Fine, A Perschl, R Haririan, Jenny Nyström, C Rehman, T Trevick, BJ Ballermann
American Journal of Physiology, Renal Physiology - 2005 -
Why do we not all have proteinuria? An update of our current understanding of the glomerular
barrier
Börje Haraldsson, Jenny Nyström
News Physiol Sci - 2004