Changlian Zhu
RESEARCHER
Department of Clinical-
Inhibiting the interaction between apoptosis-inducing factor and cyclophilin A prevents brain injury in neonatal mice after
hypoxia-ischemia
Juan Rodriguez, Cuicui Xie, Tao Li, Yanyan Sun, Yafeng Wang, Yiran Xu, Kenan Li, Shan Zhang, Kai Zhou, Yong Wang, Carina Mallard, Henrik Hagberg, Nunzianna Doti, Xiaoyang Wang, Changlian Zhu
Neuropharmacology - 2020-01-01 -
Overexpression of apoptosis inducing factor aggravates hypoxic-ischemic brain injury in neonatal
mice
Tao Li, Kenan Li, Shan Zhang, Yafeng Wang, Yiran Xu, S. J. F. Cronin, Yanyan Sun, Yaodong Zhang, Cuicui Xie, Juan Rodriguez, Kai Zhou, Henrik Hagberg, Carina Mallard, Xiaoyang Wang, J. M. Penninger, G. Kroemer, K. Blomgren, Changlian Zhu
Cell death & disease - 2020-01-01 -
Prognostic value of amplitude-integrated EEG in neonates with high risk of neurological
sequelae
X. Yuan, W. Q. Kang, J. Song, J. Guo, L. L. Guo, R. L. Zhang, S. H. Liu, Y. D. Zhang, D. P. Liu, Y. Wang, X. Ding, H. M. Dong, X. Chen, Y. H. Cheng, X. L. Zhang, F. L. Xu, Changlian Zhu
Annals of Clinical and Translational Neurology - 2020-01-01 -
Folic Acid and Risk of Preterm Birth: A
Meta-Analysis
B. B. Li, X. L. Zhang, X. R. Peng, S. Zhang, Xiaoyang Wang, Changlian Zhu
Frontiers in Neuroscience - 2019-01-01 -
The Potential Role of Ferroptosis in Neonatal Brain
Injury
Y. N. Wu, J. Song, Xiaoyang Wang, C. Culmsee, Changlian Zhu
Frontiers in Neuroscience - 2019-01-01 -
Autophagy-Related Gene 7 Polymorphisms and Cerebral Palsy in Chinese
Infants
L. Xia, J. H. Xu, J. Song, Y. R. Xu, B. H. Zhang, C. Gao, D. N. Zhu, C. C. Zhou, D. Bi, Y. G. Wang, X. L. Zhang, Q. Shang, Y. M. Qiao, X. Y. Wang, Q. H. Xing, Changlian Zhu
Frontiers in Cellular Neuroscience - 2019-01-01 -
Genetic or Other Causation Should Not Change the Clinical Diagnosis of Cerebral
Palsy.
Alastair H MacLennan, Sara Lewis, Andres Moreno-De-Luca, Michael Fahey, Richard J Leventer, Sarah McIntyre, Hilla Ben-Pazi, Mark Corbett, Xiaoyang Wang, Gareth Baynam, Darcy Fehlings, Manju A Kurian, Changlian Zhu, Kate Himmelmann, Hayley Smithers-Sheedy, Yana Wilson, Carlos Santos Ocaña, Clare van Eyk, Nadia Badawi, Richard F Wintle, Bo Jacobsson, David J Amor, Carina Mallard, Luis A Pérez-Jurado, Mikko Hallman, Peter J Rosenbaum, Michael C Kruer, Jozef Gecz
Journal of child neurology - 2019-01-01 -
Sex differences in neonatal mouse brain injury after hypoxia-ischemia and adaptaquin
treatment
Kenan Li, Tao Li, Yafeng Wang, Yiran Xu, Shan Zhang, C. Culmsee, Xiaoyang Wang, Changlian Zhu
Journal of Neurochemistry - 2019-01-01 -
Early Amplitude-Integrated Electroencephalography Predicts Long-Term Outcomes in Term and Near-Term Newborns With Severe
Hyperbilirubinemia
X. Yuan, J. Song, L. Gao, Y. C. Cheng, H. M. Dong, R. L. Zhang, S. S. Liu, X. Ding, Y. Wang, F. L. Xu, Changlian Zhu
Pediatric Neurology - 2019-01-01 -
Selective Neural Deletion of the Atg7 Gene Reduces Irradiation-Induced Cerebellar White Matter Injury in the Juvenile Mouse Brain by Ameliorating Oligodendrocyte Progenitor Cell
Loss
Yafeng Wang, Kai Zhou, Tao Li, Yiran Xu, Cuicui Xie, Yanyan Sun, Juan Rodriguez, Shan Zhang, Juan Song, Xiaoyang Wang, Klas Blomgren, Changlian Zhu
Frontiers in Cellular Neuroscience - 2019-01-01 -
MicroRNA-135a participates in the development of astrocytes derived from bacterial meningitis by downregulating HIF-1
alpha
Y. Dung, J. Wang, K. X. Du, T. M. Jia, Changlian Zhu, Y. Zhang, F. L. Xu
American Journal of Physiology-Cell Physiology - 2019-01-01 -
Iron Metabolism and Brain Development in Premature
Infants
Yafeng Wang, Y. N. Wu, Tao Li, Xiaoyang Wang, Changlian Zhu
Frontiers in Physiology - 2019-01-01 -
Variants of the OLIG2 Gene are Associated with Cerebral Palsy in Chinese Han Infants with Hypoxic-Ischemic
Encephalopathy
L. Y. Sun, L. Xia, M. T. Wang, D. N. Zhu, Y. G. Wang, D. Bi, J. Song, C. Y. Ma, C. Gao, X. L. Zhang, Y. Y. Sun, X. Y. Wang, Changlian Zhu, Q. H. Xing
Neuromolecular Medicine - 2019-01-01 -
Melatonin receptor activation provides cerebral protection after traumatic brain injury by mitigating oxidative stress and inflammation via the Nrf2 signaling
pathway
J. M. Wang, C. Jiang, K. Zhang, X. Lan, X. M. Chen, W. D. Zang, Z. Y. Wang, F. X. Guan, Changlian Zhu, X. L. Yang, H. Lu, J. Wang, Jove J. Vis Exp Jan N A
Free Radical Biology and Medicine - 2019-01-01 -
Cranial Irradiation Induces Hypothalamic Injury and Late-Onset Metabolic Disturbances in Juvenile Female
Rats.
Yiran Xu, Yanyan Sun, Kai Zhou, Tao Li, Cuicui Xie, Yaodong Zhang, Juan Rodriguez, Yanling Wu, Min Hu, Linus Ruijin Shao, Xiaoyang Wang, Changlian Zhu
Developmental neuroscience - 2018-01-01 -
Lack of the brain-specific isoform of apoptosis-inducing factor aggravates cerebral damage in a model of neonatal
hypoxia-ischemia.
Juan Rodriguez, Yaodong Zhang, Tao Li, Cuicui Xie, Yanyan Sun, Yiran Xu, Kai Zhou, Kaiming Huo, Yafeng Wang, Xiaoyang Wang, Daniel Andersson, Anders Ståhlberg, Qinghe Xing, Carina Mallard, Henrik Hagberg, Nazanine Modjtahedi, Guido Kroemer, Klas Blomgren, Changlian Zhu
Cell death & disease - 2018-01-01 -
Lymphocytes Contribute to the Pathophysiology of Neonatal Brain
Injury
Arshed Nazmi, Anna-Maj Albertsson, Eridan Rocha-Ferreira, Xiaoli Zhang, Regina Vontell, Aura Zelco, Mary Rutherford, Changlian Zhu, Gisela M A Nilsson, Carina Mallard, Henrik Hagberg, Jacqueline Lai, Jianmei W Leavenworth, Xiaoyang Wang
Frontiers in Neurology - 2018-01-01 -
γδ T cells contribute to injury in the developing
brain.
Anna-Maj Albertsson, Xiaoli Zhang, Regina Vontell, Dan Bi, Roderick T Bronson, Veena Supramaniam, Ana A Baburamani, Sha Hua, Arshed Nazmi, Susanna Cardell, Changlian Zhu, Harvey Cantor, Carina Mallard, Henrik Hagberg, Jianmei W Leavenworth, Xiaoyang Wang
The American journal of pathology - 2018-01-01 -
Lithium treatment is safe in children with intellectual
disability
J. Yuan, J. Song, D. Zhu, E. Sun, L. Xia, X. Zhang, C. Gao, G. Agam, Xiaoyang Wang, K. Blomgren, Changlian Zhu
Frontiers in Molecular Neuroscience - 2018-01-01 -
De Novo Pathogenic Variants in CACNA1E Cause Developmental and Epileptic Encephalopathy with Contractures, Macrocephaly, and
Dyskinesias
K. L. Helbig, R. J. Lauerer, J. C. Bahr, I. A. Souza, C. T. Myers, B. Uysal, N. Schwarz, M. A. Gandini, S. Huang, B. Keren, C. Mignot, A. Afenjar, T. B. de Villemeur, D. Heron, C. Nava, S. Valence, J. Buratti, C. R. Fagerberg, K. P. Soerensen, M. Kibaek, E. J. Kamsteeg, D. A. Koolen, B. Gunning, H. J. Schelhaas, M. C. Kruer, J. Fox, S. Bakhtiari, R. Jarrar, S. Padilla-Lopez, K. Lindstrom, S. C. Jin, X. Zeng, K. Bilguvar, A. Papavasileiou, Q. H. Xin, Changlian Zhu, K. Boysen, F. Vairo, B. C. Lanpher, E. W. Klee, J. M. Tillema, E. T. Payne, M. A. Cousin, T. M. Kruisselbrink, M. J. Wick, J. Baker, E. Haan, N. Smith, M. A. Corbett, A. H. MacLennan, J. Gecz, S. Biskup, E. Goldmann, L. H. Rodan, E. Kichula, E. Segal, K. E. Jackson, A. Asamoah, D. Dimmock, J. McCarrier, L. D. Botto, F. Filloux, T. Tvrdik, G. D. Cascino, S. Klingerman, C. Neumann, R. Wang, J. C. Jacobsen, M. A. Nolan, R. G. Snell, K. Lehnert, L. G. Sadleir, B. M. Anderlid, M. Kvarnung, R. Guerrini, M. J. Friez, M. J. Lyons, J. Leonhard, G. Kringlen, K. Casas, C. M. El Achkar, L. A. Smith, A. Rotenberg, A. Poduri, A. Sanchis-Juan, K. J. Carss, J. Rankin, A. Zeman, F. L. Raymond, M. Blyth, B. Kerr, K. Ruiz, J. Urquhart, I. Hughes, S. Banka, U. B. S. Hedrich, I. E. Scheffer, I. Helbig, G. W. Zamponi, H. Lerche, H. C. Mefford, Study Deciphering Dev Disorders
American Journal of Human Genetics - 2018-01-01 -
Grafting Neural Stem and Progenitor Cells Into the Hippocampus of Juvenile, Irradiated Mice Normalizes Behavior
Deficits
Yoshiaki Sato, Noriko Shinjyo, Machiko Sato, Marie Nilsson, Kazuhiro Osato, Changlian Zhu, Marcela Pekna, Hans-Georg Kuhn, Klas Blomgren
Frontiers in Neurology - 2018-01-01 -
Carbamylated Erythropoietin Decreased Proliferation and Neurogenesis in the Subventricular Zone, but Not the Dentate Gyrus, After Irradiation to the Developing Rat
Brain
Kazuhiro Osato, Yoshiaki Sato, Akari Osato, Machiko Sato, Changlian Zhu, M. Leist, Hans-Georg Kuhn, Klas Blomgren
Frontiers in Neurology - 2018-01-01 -
Association of NOS1 gene polymorphisms with cerebral palsy in a Han Chinese population: a case-control
study
T. Yu, L. Xia, D. Bi, Y. G. Wang, Q. Shang, D. N. Zhu, J. Song, Y. Wang, Xiaoyang Wang, Changlian Zhu, Q. H. Xing
Bmc Medical Genomics - 2018-01-01 -
Combined analysis of interleukin-10 gene polymorphisms and protein expression in children with cerebral
palsy
L. Xia, M. Chen, D. Bi, J. Song, X. Zhang, Y. Wang, D. Zhu, Q. Shang, F. Xu, Xiaoyang Wang, Q. Xing, Changlian Zhu
Frontiers in Neurology - 2018-01-01 -
γδT cells but not αβT cells contribute to sepsis-induced white matter injury and motor abnormalities in
mice
Xiaoli Zhang, Eridan Rocha-Ferreira, Tao Li, Regina Vontell, Darakhshan Jabin, Sha Hua, Kai Zhou, Arshed Nazmi, Anna-Maj Albertsson, Kristina Sobotka, C. Joakim Ek, Claire Thornton, Henrik Hagberg, Carina Mallard, Jianmei W. Leavenworth, Changlian Zhu, Xiaoyang Wang
Journal of Neuroinflammation - 2017-01-01 -
A Variant of the Autophagy-Related 5 Gene is Associated with Child Cerebral
Palsy
Jianhua Xu, Lei Xia, Qing Shang, Jing Du, Dengna Zhu, Yangong Wang, Dan Bi, Juan Song, Caiyun Ma, Chao Gao, Xiaoli Zhang, Yanyan Sun, Liping Zhu, Xiaoyang Wang, Changlian Zhu, Qinghe Xing
Frontiers in Cellular Neuroscience - 2017-01-01 -
Lithium protects hippocampal progenitors, cognitive performance and hypothalamus-pituitary function after irradiation to the juvenile rat
brain
Kai Zhou, Cuicui Xie, M. Wickstrom, A. M. Dolga, Yaodong Zhang, Tao Li, Yiran Xu, C. Culmsee, P. Kogner, Changlian Zhu, K. Blomgren
Oncotarget - 2017-01-01 -
Haploinsufficiency in the mitochondrial protein CHCHD4 reduces brain injury in a mouse model of neonatal
hypoxia-ischemia
Yanyan Sun, Tao Li, Cuicui Xie, Yiran Xu, Kai Zhou, Juan Rodriguez, Wei Han, Xiaoyang Wang, G. Kroemer, N. Modjtahedi, K. Blomgren, Changlian Zhu
Cell Death & Disease - 2017-01-01 -
Inhibition of autophagy prevents irradiation-induced neural stem and progenitor cell death in the juvenile mouse
brain
Yafeng Wang, Kai Zhou, Tao Li, Yiran Xu, Cuicui Xie, Yanyan Sun, Yaodong Zhang, Juan Rodriguez, K. Blomgren, Changlian Zhu
Cell Death & Disease - 2017-01-01 -
Age-dependent acute interference with stem and progenitor cell proliferation in the hippocampus after exposure to 1800 MHz electromagnetic
radiation
F. L. Xu, Q. D. Bai, Kai Zhou, L. Ma, J. J. Duan, F. L. Zhuang, Cuicui Xie, W. L. Li, P. Zou, Changlian Zhu
Electromagnetic Biology and Medicine - 2017-01-01 -
Cranial irradiation induces transient microglia accumulation, followed by long-lasting inflammation and loss of
microglia
W. Han, T. Umekawa, K. Zhou, X. M. Zhang, M. Ohshima, C. A. Dominguez, R. A. Harris, Changlian Zhu, K. Blomgren
Oncotarget - 2016-01-01 -
Association of COL4A1 gene polymorphisms with cerebral palsy in a Chinese Han
population
D. Bi, H. Wang, Q. Shang, Y. Xu, F. Wang, M. Chen, C. Ma, Y. Sun, X. Zhao, C. Gao, L. Wang, Changlian Zhu, Q. Xing
Clinical Genetics - 2016-01-01 -
Neuroprotection by selective neuronal deletion of Atg7 in neonatal brain
injury
Cuicui Xie, V. Ginet, Yanyan Sun, M. Koike, Kai Zhou, Tao Li, Hongfu Li, Qian Li, Xiaoyang Wang, Y. Uchiyama, A. C. Truttmann, G. Kroemer, J. Puyal, K. Blomgren, Changlian Zhu
Autophagy - 2016-01-01 -
Acute and Long-Term Effects of Brief Sevoflurane Anesthesia During the Early Postnatal Period in
Rats
Lin Qiu, Changlian Zhu, T. Bodogan, M. Gomez-Galan, Yaodong Zhang, Kai Zhou, T. Li, G. X. Xu, Klas Blomgren, L. I. Eriksson, L. Vutskits, N. Terrando
Toxicological Sciences - 2016-01-01 -
Recombinant Human Erythropoietin Improves Neurological Outcomes in Very Preterm
Infants
J. Song, H. Q. Sun, F. L. Xu, W. Q. Kang, L. Gao, J. J. Guo, Y. H. Zhang, L. Xia, Xiaoyang Wang, Changlian Zhu
Annals of Neurology - 2016-01-01 -
Dichloroacetate treatment improves mitochondrial metabolism and reduces brain injury in neonatal
mice
Yanyan Sun, Tao Li, Cuicui Xie, Yaodong Zhang, Kai Zhou, Xiaoyang Wang, Klas Blomgren, Changlian Zhu
Oncotarget - 2016-01-01 -
Association Between Osteopontin Gene Polymorphisms and Cerebral Palsy in a Chinese
Population
Q. Shang, C. C. Zhou, D. Z. Liu, W. X. Li, M. J. Chen, Y. R. Xu, F. Wang, D. Bi, X. L. Zhang, X. Z. Zhao, L. Wang, Changlian Zhu, Q. H. Xing
Neuromolecular Medicine - 2016-01-01 -
GSK3β inhibition protects the immature brain from hypoxic-ischaemic insult via reduced STAT3
signalling
Barbara D'angelo, C. Joakim Ek, Yanyan Sun, Changlian Zhu, Mats Sandberg, Carina Mallard
Neuropharmacology - 2016-01-01 -
Interaction between AIF and CHCHD4 Regulates Respiratory Chain
Biogenesis
Emilie Hangen, Olivier Féraud, Sylvie Lachkar, Haiwei Mou, Nunzianna Doti, Gian Maria Fimia, Ngoc-Vy Lam, Changlian Zhu, Isabelle Godin, Kevin Muller, Afroditi Chatzi, Esther Nuebel, Fabiola Ciccosanti, Stéphane Flamant, Paule Bénit, Jean-Luc Perfettini, Allan Sauvat, Annelise Bennaceur-Griscelli, Karine Ser-Le Roux, Patrick Gonin, Kostas Tokatlidis, Pierre Rustin, Mauro Piacentini, Menotti Ruvo, Klas Blomgren, Guido Kroemer, Nazanine Modjtahedi
Molecular cell - 2015-01-01 -
Early amplitude-integrated electroencephalography predicts brain injury and neurological outcome in very preterm
infants
J. Song, F. L. Xu, L. S. Wang, L. Gao, J. J. Guo, L. Xia, Y. H. Zhang, W. H. Zhou, Xiaoyang Wang, Changlian Zhu
Scientific Reports - 2015-01-01 -
Beneficence and Nonmaleficence in Treating Neonatal Hypoxic-Ischemic Brain
Injury
M. Tagin, Changlian Zhu, A. J. Gunn
Developmental Neuroscience - 2015-01-01 -
Changes in the Incidence of Congenital Anomalies in Henan Province, China, from 1997 to
2011
L. Xia, L. H. Sun, X. L. Wang, M. L. Yao, F. L. Xu, G. M. Cheng, Xiaoyang Wang, Changlian Zhu
Plos One - 2015-01-01 -
Irradiation of the Juvenile Brain Provokes a Shift from Long-Term Potentiation to Long-Term
Depression
Giulia Zanni, Kai Zhou, Ilse Riebe, Cuicui Xie, Changlian Zhu, Eric Hanse, K. Blomgren
Developmental Neuroscience - 2015-01-01 -
Clinical study of cerebral palsy in 408 children with periventricular
leukomalacia
Q. Shang, C. Y. Ma, N. Lv, Z. L. Lv, Y. B. Yan, Z. R. Wu, J. J. Li, J. L. Duan, Changlian Zhu
Experimental and Therapeutic Medicine - 2015-01-01 -
Transplantation of Enteric Neural Stem/Progenitor Cells into the Irradiated Young Mouse
Hippocampus.
Ahmed M Osman, Kai Zhou, Changlian Zhu, Klas Blomgren
Cell transplantation - 2014-01-01 -
The immune response after hypoxia-ischemia in a mouse model of preterm brain
injury.
Anna-Maj Albertsson, Dan Bi, Luqi Duan, Xiaoli Zhang, Jianmei W Leavenworth, Lili Qiao, Changlian Zhu, Susanna Cardell, Harvey Cantor, Henrik Hagberg, Carina Mallard, Xiaoyang Wang
Journal of neuroinflammation - 2014-01-01 -
Therapeutic Benefits of Delayed Lithium Administration in the Neonatal Rat after Cerebral
Hypoxia-Ischemia
Cuicui Xie, Kai Zhou, Xiaoyang Wang, Klas Blomgren, Changlian Zhu
Plos One - 2014-01-01 -
The association between sex-related interleukin-6 gene polymorphisms and the risk for cerebral
palsy
D. Bi, M. J. Chen, X. L. Zhang, H. L. Wang, L. Xia, Q. Shang, T. C. Li, D. N. Zhu, Klas Blomgren, L. He, Xiaoyang Wang, Q. H. Xing, Changlian Zhu
Journal of Neuroinflammation - 2014-01-01 -
The association of apolipoprotein E gene polymorphisms with cerebral palsy in Chinese
infants
Y. R. Xu, H. L. Wang, Y. Y. Sun, Q. Shang, M. J. Chen, T. C. Li, D. N. Zhu, L. He, Changlian Zhu, Q. H. Xing
Molecular Genetics and Genomics - 2014-01-01 -
Delayed, Long-Term Administration of the Caspase Inhibitor Q-VD-OPh Reduced Brain Injury Induced by Neonatal
Hypoxia-Ischemia.
Wei Han, Yanyan Sun, Xiaoyang Wang, Changlian Zhu, Klas Blomgren
Developmental neuroscience - 2014-01-01 -
Inhaled nitric oxide protects males but not females from neonatal mouse hypoxia-ischemia brain
injury
Changlian Zhu, Yanyan Sun, Jianfeng Gao, Xiaoyang Wang, Nikolaus Plesnila, Klas Blomgren
Translational Stroke Research - 2013-01-01 -
Genetic association study of adaptor protein complex 4 with cerebral palsy in a Han Chinese
population
H. L. Wang, Y. R. Xu, M. J. Chen, Q. Shang, Y. Y. Sun, D. N. Zhu, Lei Wang, Z. H. Huang, C. Y. Ma, T. C. Li, L. He, Q. H. Xing, Changlian Zhu
Molecular Biology Reports - 2013-01-01 -
The Use of the WINROP Screening Algorithm for the Prediction of Retinopathy of Prematurity in a Chinese
Population
H. Q. Sun, W. Q. Kang, X. Y. Cheng, C. Chen, H. Xiong, J. Guo, C. C. Zhou, Y. H. Zhang, Ann Hellström, Chatarina Löfqvist, Changlian Zhu
Neonatology - 2013-01-01 -
Characteristics of Respiratory Distress Syndrome in Infants of Different Gestational
Ages
H. Q. Sun, F. L. Xu, H. Xiong, W. Q. Kang, Q. D. Bai, Y. H. Zhang, C. C. Zhou, F. L. Zhuang, Xiaoyang Wang, Changlian Zhu
Lung - 2013-01-01 -
Grafting of neural stem and progenitor cells to the hippocampus of young, irradiated mice causes gliosis and disrupts the granule cell
layer.
Yoshiaki Sato, Noriko Shinjyo, Machiko Sato, Kazuhiro Osato, Changlian Zhu, Marcela Pekna, Hans-Georg Kuhn, Klas Blomgren
Cell Death & Disease - 2013-01-01 -
Association of Interleukin 6 gene polymorphisms with genetic susceptibilities to spastic tetraplegia in males: A case-control
study
M. J. Chen, T. C. Li, S. Y. Lin, D. Bi, D. N. Zhu, Q. Shang, C. Y. Ma, H. L. Wang, L. Wang, Y. T. Zhang, L. He, Changlian Zhu, Q. H. Xing
Cytokine - 2013-01-01 -
Guidelines for the use and interpretation of assays for monitoring
autophagy
Daniel Klionsky, Fabio Abdalla, Hagai Abeliovich, Robert T. Abraham, Abraham Acevedo-Arozena, Khosrow Adeli, Lotta Agholme, Maria Agnello, Changlian Zhu, Brian Zuckerbraun
Autophagy - 2012-01-01 -
Lithium reduced neural progenitor apoptosis in the hippocampus and ameliorated functional deficits after irradiation to the immature mouse
brain.
Kaiming Huo, Yanyan Sun, Hongfu Li, Xiaonan Du, Xiaoyang Wang, Niklas Karlsson, Changlian Zhu, Klas Blomgren
Molecular and cellular neurosciences - 2012-01-01 -
Maternal mortality in Henan Province, China: changes between 1996 and
2009.
Fengzhi You, Kaiming Huo, Ruili Wang, Dongmei Xu, Jie Deng, Ying Wei, Fenglian Shi, Hongyang Liu, Guomei Cheng, Zhan Zhang, Ping Yang, Tao Sun, Xiaoyang Wang, Bo Jacobsson, Changlian Zhu
PloS one - 2012-01-01 -
Apoptosis-inducing factor downregulation increased neuronal progenitor, but not stem cell, survival in the neonatal hippocampus after cerebral
hypoxiaischemia.
Yanyan Sun, Yu Zhang, Xiaoyang Wang, Klas Blomgren, Changlian Zhu
Molecular neurodegeneration - 2012-01-01 -
Decreased oxidative stress during glycolytic inhibition enables maintenance of ATP production and astrocytic
survival.
Christina Nodin, Changlian Zhu, Klas Blomgren, Michael Nilsson, Fredrik Blomstrand
Neurochemistry international - 2012-01-01 -
Inhalation of nitric oxide prevents ischemic brain damage in experimental stroke by selective dilatation of collateral
arterioles.
Nicole A Terpolilli, Seong-Woong Kim, Serge C Thal, Hiroharu Kataoka, Vilia Zeisig, Bjoern Nitzsche, Benjamin Klaesner, Changlian Zhu, Susanne Schwarzmaier, Lilja Meissner, Uta Mamrak, Doortje C Engel, Alexander Drzezga, Rakesh P Patel, Klas Blomgren, Henryk Barthel, Johannes Boltze, Wolfgang M Kuebler, Nikolaus Plesnila
Circulation research - 2012-01-01 -
Risk factors for neurodevelopmental deficits in congenital hypothyroidism after early substitution
treatment.
Kaiming Huo, Zhan Zhang, Dehua Zhao, Hezhou Li, Jun Wang, Xinxia Wang, Hongqi Feng, Xiaoyang Wang, Changlian Zhu
Endocrine journal - 2011-01-01 -
Isolation of brain mitochondria from neonatal
mice.
Xiaoyang Wang, Anna-Lena Leverin, Wei Han, Changlian Zhu, Bengt R Johansson, Etienne Jacotot, Vadim S Ten, Neil R Sims, Henrik Hagberg
Journal of neurochemistry - 2011-01-01 -
Systemic stimulation of TLR2 impairs neonatal mouse brain
development.
Xiaonan Du, Bobbi Fleiss, Hongfu Li, Barbara D'angelo, Yanyan Sun, Changlian Zhu, Henrik Hagberg, Ofer Levy, Carina Mallard, Xiaoyang Wang
PloS one - 2011-01-01 -
Lithium-mediated long-term neuroprotection in neonatal rat hypoxia-ischemia is associated with antiinflammatory effects and enhanced proliferation and survival of neural stem/progenitor
cells.
Hongfu Li, Qian Li, Xiaonan Du, Yanyan Sun, Xiaoyang Wang, Guido Kroemer, Klas Blomgren, Changlian Zhu
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism - 2011-01-01 -
Biochemical and molecular biological assessments of NHI - cell
signaling.
Changlian Zhu, Klas Blomgren
Animal Models of Acute Neurological Injuries II: Injury and Mechanistic Assessments. Eds. Jun Chen Zao C. Xu, Xiao-Ming Xu, and John H. Zheng. - 2011-01-01 -
Morphological Assessment of Neonatal Hypoxia-Ischemia - in situ Cell
Degeneration.
Changlian Zhu, Klas Blomgren
Animal Models of Acute Neurological Injuries II: Injury and Mechanistic Assessments. Eds. Jun Chen Zao C. Xu, Xiao-Ming Xu, and John H. Zheng. - 2011-01-01 -
Repeated exposure of the developing rat brain to magnetic resonance imaging did not affect neurogenesis, cell death or memory
function.
Changlian Zhu, Jianfeng Gao, Qian Li, Zhiheng Huang, Yu Zhang, Hongfu Li, Hans-Georg Kuhn, Klas Blomgren
Biochemical and biophysical research communications - 2011-01-01 -
Role of apoptosis inducing factor (AIF) for hippocampal neuronal cell death following global cerebral ischemia in
mice.
Simone E Thal, Changlian Zhu, Serge C Thal, Klas Blomgren, Nikolaus Plesnila
Neuroscience letters - 2011-01-01 -
Induction of ER stress in response to oxygen-glucose deprivation of cortical cultures involves the activation of the PERK and IRE-1 pathways and of
caspase-12.
N Badiola, C Penas, A Miñano-Molina, B Barneda-Zahonero, R Fadó, G Sánchez-Opazo, J X Comella, J Sabriá, Changlian Zhu, Klas Blomgren, C Casas, J Rodríguez-Alvarez
Cell death & disease - 2011-01-01 -
Mortality rates of children aged under five in Henan province, China,
2004-2008
Kaiming Huo, Yueshu Zhao, Hongqi Feng, Meiling Yao, Karin Sävman, Xiaoyang Wang, Changlian Zhu
PAEDIATRIC AND PERINATAL EPIDEMIOLOGY - 2010-01-01 -
Apoptosis-inducing factor deficiency decreases the proliferation rate and protects the subventricular zone against ionizing
radiation.
Kazuhiro Osato, Yoshiaki Sato, T Ochiishi, A Osato, Changlian Zhu, Machiko Sato, John Swanpalmer, N Modjtahedi, G Kroemer, Hans-Georg Kuhn, Klas Blomgren
Cell death & disease - 2010-01-01 -
Neuroprotective effect of Bax-inhibiting peptide on neonatal brain
injury
Xiaoyang Wang, W. Han, X. Du, Changlian Zhu, Ylva Carlsson, Carina Mallard, E. Jacotot, Henrik Hagberg
Stroke - 2010-01-01 -
Lithium reduces apoptosis and autophagy after neonatal
hypoxia–ischemia
Qian Li, H. Li, Karolina Roughton, Xiaoyang Wang, G Kroemer, Klas Blomgren, Changlian Zhu
Cell death and Disease - 2010-01-01 -
Isoflurane anesthesia induced persistent, progressive memory impairment, caused a loss of neural stem cells, and reduced neurogenesis in young, but not adult,
rodents.
Changlian Zhu, Jianfeng Gao, Niklas Karlsson, Qian Li, Yu Zhang, Zhiheng Huang, Hongfu Li, Hans-Georg Kuhn, Klas Blomgren
Journal of cerebral blood flow and metabolism - 2010-01-01 -
A brain-specific isoform of mitochondrial apoptosis-inducing factor:
AIF2.
E Hangen, D De Zio, M Bordi, Changlian Zhu, P Dessen, F Caffin, S Lachkar, J-L Perfettini, V Lazar, J Benard, G M Fimia, M Piacentini, F Harper, G Pierron, J M Vicencio, P Bénit, A de Andrade, G Höglinger, C Culmsee, P Rustin, Klas Blomgren, F Cecconi, G Kroemer, N Modjtahedi
Cell death and differentiation - 2010-01-01 -
Nuclear translocation and calpain-dependent reduction of Bcl-2 after neonatal cerebral
hypoxia-ischemia
Changlian Zhu, Ulrika Hallin, Y. Ozaki, Rita Grandér, Kliment Gatzinsky, B. A. Bahr, Jan-Olof Karlsson, F. Shibasaki, Henrik Hagberg, Klas Blomgren
Brain, Behavior, and Immunity - 2010-01-01 -
Irradiation to the immature brain attenuates neurogenesis and exacerbates subsequent hypoxic-ischemic brain injury in the
adult.
Changlian Zhu, Zhiheng Huang, Jianfeng Gao, Yu Zhang, Xiaoyang Wang, Niklas Karlsson, Thomas Björk-Eriksson, Qian Li, Birgitta Lannering, Hans-Georg Kuhn, Klas Blomgren
Journal of neurochemistry - 2009-01-01 -
Systemic hypothermia induced within 10 hours after birth improved neurological outcome in newborns with hypoxic-ischemic
encephalopathy
T Li, F. Xu, X. Cheng, X Guo, Z. Zhang, X Wang, Klas Blomgren, George Simbruner, Changlian Zhu
Hospital Practice - 2009-01-01 -
Reduced liver injury and cytokine release after transplantation of preconditioned
intestines.
Mihai Oltean, Changlian Zhu, Simona Mera, Rille Pullerits, Inger Mattsby-Baltzer, Johan Mölne, Eva Hallberg, Klas Blomgren, Michael Olausson
The Journal of surgical research - 2009-01-01 -
Developmental shift of cyclophilin D contribution to hypoxic-ischemic brain
injury.
Xiaoyang Wang, Ylva Carlsson, Emy Basso, Changlian Zhu, Catherine Rousset, Andrea Rasola, Bengt R Johansson, Klas Blomgren, Carina Mallard, Paolo Bernardi, Michael A Forte, Henrik Hagberg
The Journal of neuroscience : the official journal of the Society for Neuroscience - 2009-01-01 -
Erythropoietin improved neurologic outcomes in newborns with hypoxic-ischemic
encephalopathy.
Changlian Zhu, Wenqing Kang, Falin Xu, Xiuyong Cheng, Zhan Zhang, Liting Jia, Ling Ji, Xiaoyan Guo, Hong Xiong, George Simbruner, Klas Blomgren, Xiaoyang Wang
Pediatrics - 2009-01-01 -
Age-dependent regenerative responses in the striatum and cortex after
hypoxia-ischemia.
Changlian Zhu, Lin Qiu, Xiaoyang Wang, Falin Xu, Michael Nilsson, Christiana M Cooper-Kuhn, Hans-Georg Kuhn, Klas Blomgren
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism - 2009-01-01 -
Voluntary running rescues adult hippocampal neurogenesis after irradiation of the young mouse
brain.
Andrew Stuart Naylor, Cecilia Bull, Marie Nilsson, Changlian Zhu, Thomas Björk-Eriksson, Peter S Eriksson, Klas Blomgren, Hans-Georg Kuhn
Proceedings of the National Academy of Sciences of the United States of America - 2008-01-01 -
Proliferative and protective effects of growth hormone secretagogues on adult rat hippocampal progenitor
cells.
Inger Johansson, Silvia Destefanis, N David Åberg, Maria A I Åberg, Klas Blomgren, Changlian Zhu, Corrado Ghè, Riccarda Granata, Ezio Ghigo, Giampiero Muccioli, Peter S Eriksson, Jörgen Isgaard
Endocrinology - 2008-01-01 -
Causal role of apoptosis-inducing factor for neuronal cell death following traumatic brain
injury.
Jennifer E Slemmer, Changlian Zhu, Stefan Landshamer, Raimund Trabold, Julia Grohm, Ardavan Ardeshiri, Ernst Wagner, Marva I Sweeney, Klas Blomgren, Carsten Culmsee, John T Weber, Nikolaus Plesnila
The American journal of pathology - 2008-01-01 -
Regulation of autophagy by cytoplasmic
p53.
Ezgi Tasdemir, M Chiara Maiuri, Lorenzo Galluzzi, Ilio Vitale, Mojgan Djavaheri-Mergny, Marcello D'Amelio, Alfredo Criollo, Eugenia Morselli, Changlian Zhu, Francis Harper, Ulf Nannmark, Chrysanthi Samara, Paolo Pinton, José Miguel Vicencio, Rosa Carnuccio, Ute M Moll, Frank Madeo, Patrizia Paterlini-Brechot, Rosario Rizzuto, Gyorgy Szabadkai, Gérard Pierron, Klas Blomgren, Nektarios Tavernarakis, Patrice Codogno, Francesco Cecconi, Guido Kroemer
Nature cell biology - 2008-01-01 -
Cerebral Hypoxia-Ischemia in Neonatal Rats or Mice - A Model of Perinatal Brain Injury In: Section III: Neonatal
Hypoxia-Ischemia
Changlian Zhu, Xiaoyang Wang, Klas Blomgren
Animal Models of Acute Neurological Injuries. Chen, J.; Xu, Z.C.; Xu, X.-M.; Zhang, J.H. (Eds.) - 2008-01-01 -
Developing postmitotic mammalian neurons in vivo lacking Apaf-1 undergo programmed cell death by a caspase-independent, nonapoptotic pathway involving
autophagy.
Ronald W Oppenheim, Klas Blomgren, Douglas W Ethell, Masato Koike, Masaaki Komatsu, David Prevette, Kevin A Roth, Yasuo Uchiyama, Sharon Vinsant, Changlian Zhu
The Journal of neuroscience : the official journal of the Society for Neuroscience - 2008-01-01 -
Apoptosis-inducing factor is a major contributor to neuronal loss induced by neonatal cerebral
hypoxia-ischemia
Changlian Zhu, Xiaoyang Wang, Z. Huang, L. Qiu, F. Xu, N. Vahsen, Michael Nilsson, Peter S Eriksson, Henrik Hagberg, C. Culmsee, N. Plesnila, G. Kroemer, Klas Blomgren
Cell Death Differ - 2007-01-01 -
Ciliated epithelial-specific and regional-specific expression and regulation of the estrogen receptor-beta2 in the fallopian tubes of immature rats: a possible mechanism for estrogen-mediated transport process in
vivo
Linus Ruijin Shao, Birgitta Weijdegård, Julia Fernandez-Rodriguez, Emil Egecioglu, Changlian Zhu, Niklas Andersson, Ann Thurin-Kjellberg, Christina Bergh, Håkan Billig
American journal of physiology - 2007-01-01 -
Less neurogenesis and inflammation in the immature than in the juvenile brain after cerebral
hypoxia-ischemia
L. Qiu, Changlian Zhu, Xiaoyang Wang, F. Xu, Peter S Eriksson, Michael Nilsson, Christiana M Cooper-Kuhn, Hans-Georg Kuhn, Klas Blomgren
J Cereb Blood Flow Metab - 2007-01-01 -
Matrix metalloproteinase-9 gene knock-out protects the immature brain after cerebral
hypoxia-ischemia
Pernilla Svedin, Henrik Hagberg, Karin Sävman, Changlian Zhu, Carina Mallard
J Neurosci - 2007-01-01 -
Donor pretreatment with FK506 reduces reperfusion injury and accelerates intestinal graft recovery in
rats
Mihai Oltean, Rille Pullerits, Changlian Zhu, Klas Blomgren, Eva Hallberg, Michael Olausson
Surgery - 2007-01-01 -
Antioxidant status alters levels of Fas-associated death domain-like IL-1B-converting enzyme inhibitory protein following neonatal
hypoxia-ischemia
K. S. Payton, R. A. Sheldon, D. W. Mack, Changlian Zhu, Klas Blomgren, D. M. Ferriero, F. J. Northington
Dev Neurosci - 2007-01-01 -
N-acetylcysteine reduces lipopolysaccharide-sensitized hypoxic-ischemic brain
injury.
Xiaoyang Wang, Pernilla Svedin, Chunxia Nie, Risto Lapatto, Changlian Zhu, Malin Gustavsson, Mats Sandberg, Jan-Olof Karlsson, Roberto Romero, Henrik Hagberg, Carina Mallard
Annals of neurology - 2007-01-01 -
X chromosome-linked inhibitor of apoptosis protein reduces oxidative stress after cerebral irradiation or hypoxia-ischemia through up-regulation of mitochondrial
antioxidants.
Changlian Zhu, Falin Xu, Aya Fukuda, Xiaoyang Wang, Hirotsugu Fukuda, Laura Korhonen, Henrik Hagberg, Birgitta Lannering, Michael Nilsson, Peter S Eriksson, Frances J Northington, Thomas Björk-Eriksson, Dan Lindholm, Klas Blomgren
The European journal of neuroscience - 2007-01-01 -
Cyclophilin A participates in the nuclear translocation of apoptosis-inducing factor in neurons after cerebral
hypoxia-ischemia
Changlian Zhu, Xiaoyang Wang, J. Deinum, Z. Huang, J. Gao, N. Modjtahedi, M. R. Neagu, Michael Nilsson, Peter S Eriksson, Henrik Hagberg, J. Luban, G. Kroemer, Klas Blomgren
J Exp Med - 2007-01-01 -
Death effector activation in the subventricular zone subsequent to perinatal
hypoxia/ischemia
M. J. Romanko, Changlian Zhu, B. A. Bahr, Klas Blomgren, S. W. Levison
J Neurochem - 2007-01-01 -
Effects of intrauterine inflammation on the developing mouse
brain
Xiaoyang Wang, Henrik Hagberg, Changlian Zhu, Bo Jacobsson, Carina Mallard
Brain Res - 2007-01-01 -
Dual role of intrauterine immune challenge on neonatal and adult brain vulnerability to
hypoxia-ischemia
Xiaoyang Wang, Henrik Hagberg, Chunxia Nie, Changlian Zhu, Tomoaki Ikeda, Carina Mallard
J Neuropathol Exp Neurol - 2007-01-01 -
Transplantation of preconditioned intestinal grafts is associated with lower inflammatory activation and remote organ injury in
rats
Mihai Oltean, Simona Mera, Roger Olofsson, Changlian Zhu, Klas Blomgren, E. Hallberg, Michael Olausson
Transplant Proc - 2006-01-01 -
Neuroprotective properties of memantine in different in vitro and in vivo models of
excitotoxicity
C. Volbracht, J. van Beek, Changlian Zhu, Klas Blomgren, M. Leist
Eur J Neurosci - 2006-01-01 -
Different apoptotic mechanisms are activated in male and female brains after neonatal
hypoxia-ischaemia
Changlian Zhu, Falin Xu, Xiaoyang Wang, M. Shibata, Y. Uchiyama, Klas Blomgren, Henrik Hagberg
J Neurochem - 2006-01-01 -
Nuclear progesterone receptor A and B isoforms in mouse fallopian tube and uterus: implications for expression, regulation, and cellular
function
Linus Ruijin Shao, Birgitta Weijdegård, Karin Ljungström, P. Anders Friberg, Changlian Zhu, Xiaoyang Wang, Yihong Zhu, Julia Fernandez-Rodriguez, Emil Egecioglu, Emilia Rung, Håkan Billig
American journal of physiology - 2006-01-01 -
Intraischemic mild hypothermia prevents neuronal cell death and tissue loss after neonatal cerebral
hypoxia-ischemia
Changlian Zhu, Xiaoyang Wang, F. Xu, L. Qiu, X. Cheng, G. Simbruner, Klas Blomgren
Eur J Neurosci - 2006-01-01 -
Disruption of interleukin-18, but not interleukin-1, increases vulnerability to preterm delivery and fetal mortality after intrauterine
inflammation
Xiaoyang Wang, Henrik Hagberg, Carina Mallard, Changlian Zhu, Maj Hedtjärn, Carl Fredrik Tiger, Kristina Eriksson, Åsa Rosen, Bo Jacobsson
Am J Pathol - 2006-01-01 -
Apoptosis-inducing factor triggered by poly(ADP-ribose) polymerase and Bid mediates neuronal cell death after oxygen-glucose deprivation and focal cerebral
ischemia
C. Culmsee, Changlian Zhu, S. Landshamer, B. Becattini, E. Wagner, M. Pellecchia, Klas Blomgren, N. Plesnila
J Neurosci - 2005-01-01 -
FK506 donor pretreatment improves intestinal graft microcirculation and morphology by concurrent inhibition of early NF-kappaB activation and augmented HSP72
synthesis
Mihai Oltean, Roger Olofsson, Changlian Zhu, Simona Mera, Klas Blomgren, Michael Olausson
Transplant Proc - 2005-01-01 -
The influence of age on apoptotic and other mechanisms of cell death after cerebral
hypoxia-ischemia
Changlian Zhu, Xiaoyang Wang, F. Xu, B. A. Bahr, M. Shibata, Y. Uchiyama, Henrik Hagberg, Klas Blomgren
Cell Death Differ - 2005-01-01 -
Nuclear translocation of apoptosis-inducing factor after focal cerebral
ischemia
N. Plesnila, Changlian Zhu, C. Culmsee, M. Groger, M. A. Moskowitz, Klas Blomgren
J Cereb Blood Flow Metab - 2004-01-01 -
Nitrosylation precedes caspase-3 activation and translocation of apoptosis-inducing factor in neonatal rat cerebral
hypoxia-ischaemia
Changlian Zhu, Xiaoyang Wang, L. Qiu, C. Peeters-Scholte, Henrik Hagberg, Klas Blomgren
J Neurochem - 2004-01-01 -
Post-ischemic hypothermia-induced tissue protection and diminished apoptosis after neonatal cerebral
hypoxia-ischemia
Changlian Zhu, Xiaoyang Wang, X. Cheng, L. Qiu, F. Xu, G. Simbruner, Klas Blomgren
Brain Res - 2004-01-01 -
The nonerythropoietic asialoerythropoietin protects against neonatal hypoxia-ischemia as potently as
erythropoietin.
Xiaoyang Wang, Changlian Zhu, Xinhua Wang, Jens Gammeltoft Gerwien, Andre Schrattenholz, Mats Sandberg, Marcel Leist, Klas Blomgren
Journal of neurochemistry - 2004-01-01 -
PARP-1 gene disruption in mice preferentially protects males from perinatal brain
injury
Henrik Hagberg, Mary Ann Wilson, Hiroko Matsushita, Changlian Zhu, Mary Lange, Malin Gustavsson, Marc F. Poitras, Ted. M. Dawson, Valina. L. Dawson, Frances. Northington, Michael. V. Johnston
J Neurochem - 2004-01-01 -
Caspase-independent. AIF-mediated cell death after hypoxia-ischemia in the developing
brain.
Klas Blomgren, C Zhu, Henrik Hagberg, Changlian Zhu
Proceeding from the 10th International Symposium on Pharmacology of Cerebral Ischemia, Marburg, July 25-28 - 2004-01-01 -
Caspase-dependent and caspase-independent neuronal injury in the developing
brain
Changlian Zhu
- 2004-01-01 -
X-linked inhibitor of apoptosis (XIAP) protein protects against caspase activation and tissue loss after neonatal
hypoxia-ischemia
Xiaoyang Wang, Changlian Zhu, X Wang, Henrik Hagberg, L. Korhonen, Mats Sandberg, D. Lindholm, Klas Blomgren
Neurobiol Dis - 2004-01-01 -
Irradiation-induced progenitor cell death in the developing brain is resistant to erythropoietin treatment and caspase
inhibition
Hirotsugu Fukuda, A. Fukuda, Changlian Zhu, L. Korhonen, John Swanpalmer, Sven Hertzman, M. Leist, Birgitta Lannering, D. Lindholm, Thomas Björk-Eriksson, Ildiko Marky, Klas Blomgren
Cell Death Differ - 2004-01-01