Jörg Hanrieder
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Mass Spectrometry Imaging in Alzheimer's
Disease
M. Ikegawa, N. Kakuda, T. Miyasaka, Y. Toyama, T. Nirasawa, Karolina Minta, Jörg Hanrieder
Brain Connectivity - 2023 -
Investigating New Applications of a Photoswitchable Fluorescent Norbornadiene as a Multifunctional Probe for Delineation of Amyloid Plaque
Polymorphism.
Ambra Dreos, Junyue Ge, Francisco Najera, Behabitu Ergette Tebikachew, Ezequiel Perez-Inestrosa, Kasper Moth-Poulsen, Kaj Blennow, Henrik Zetterberg, Jörg Hanrieder
ACS sensors - 2023 -
Correlative Chemical Imaging and Spatial Chemometrics Delineate Alzheimer Plaque Heterogeneity at High Spatial
Resolution
Patrick M. Wehrli, J. Y. Ge, Wojciech Michno, Srinivas Koutarapu, Ambra Dreos, Durga Jha, Henrik Zetterberg, Kaj Blennow, Jörg Hanrieder
Jacs Au - 2023 -
Tetramodal Chemical Imaging Delineates the Lipid-Amyloid Peptide Interplay at Single Plaques in Transgenic Alzheimer?s Disease
Models
Junyue Ge, Srinivas Koutarapu, Durga Jha, Maciej Dulewicz, Henrik Zetterberg, Kaj Blennow, Jörg Hanrieder
Analytical Chemistry - 2023 -
Correlative Chemical Imaging Identifies Amyloid Peptide Signatures of Neuritic Plaques and Dystrophy in Human Sporadic Alzheimer's
Disease.
Srinivas Koutarapu, Junyue Ge, Durga Jha, Kaj Blennow, Henrik Zetterberg, Tammaryn Lashley, Wojciech Michno, Jörg Hanrieder
Brain connectivity - 2022 -
Plaque contact and unimpaired Trem2 is required for the microglial response to amyloid
pathology
Jack Wood, E. Wong, R. Joghee, A. Balbaa, K. S. Vitanova, Katie Stringer, A. Vanshoiack, S. L. J. Phelan, F. Launchbury, S. Desai, T. Tripathi, Jörg Hanrieder, D. M. Cummings, J. Hardy, F. A. Edwards
Cell Reports - 2022 -
Chemical traits of cerebral amyloid angiopathy in familial British-, Danish-, and non-Alzheimer 's
dementias
Wojciech Michno, Srinivas Koutarapu, Rafael Camacho, C. Toomey, Katie Stringer, Karolina Minta, Junyue Ge, Durga Jha, Julia Fernandez-Rodriguez, Gunnar Brinkmalm, Henrik Zetterberg, Kaj Blennow, N. S. Ryan, T. Lashley, Jörg Hanrieder
Journal of Neurochemistry - 2022 -
Structural amyloid plaque polymorphism is associated with distinct lipid accumulations revealed by trapped ion mobility mass spectrometry
imaging
Wojciech Michno, Patrick M. Wehrli, Srinivas Koutarapu, C. Marsching, Karolina Minta, Junyue Ge, S. W. Meyer, Henrik Zetterberg, Kaj Blennow, C. Henkel, J. Oetjen, C. Hopf, Jörg Hanrieder
Journal of Neurochemistry - 2022 -
Following spatial Aβ aggregation dynamics in evolving Alzheimer's disease pathology by imaging stable isotope labeling
kinetics
Wojciech Michno, K. M. Stringer, T. Enzlein, M. K. Passarelli, S. Escrig, K. Vitanova, J. Wood, Kaj Blennow, Henrik Zetterberg, A. Meibom, C. Hopf, F. A. Edwards, Jörg Hanrieder
Science Advances - 2021 -
Herpes Simplex Virus 1 and 2 Infections during Differentiation of Human Cortical
Neurons
Petra Bergström, Edward Trybala, Charlotta Eriksson, Maria Johansson, Tugce Munise Satir, Sibylle Widehn, Stefanie Fruhwürth, W. Michno, Faisal Hayat Nazir, Jörg Hanrieder, Sören R Paludan, Lotta Agholme, Henrik Zetterberg, Tomas Bergström
Viruses-Basel - 2021 -
Knock-in models related to Alzheimer's disease: synaptic transmission, plaques and the role of
microglia
D. P. Benitez, S. Y. Jiang, J. Wood, R. Wang, C. M. Hall, C. Peerboom, N. Wong, Katie Stringer, K. S. Vitanova, V. C. Smith, D. Joshi, T. Saito, T. C. Saido, J. Hardy, Jörg Hanrieder, B. De Strooper, D. A. Salih, T. Tripathi, F. A. Edwards, D. M. Cummings
Molecular Neurodegeneration - 2021 -
Perspectives in fluid biomarkers in neurodegeneration from the 2019 biomarkers in neurodegenerative diseases course-a joint PhD student course at University College London and University of
Gothenburg.
Pawel Obrocki, Ayesha Khatun, Deborah Ness, Konstantin Senkevich, Jörg Hanrieder, Federica Capraro, Niklas Mattsson, Ulf Andreasson, Erik Portelius, Nicholas J. Ashton, Kaj Blennow, Michael Schöll, Ross W Paterson, Jonathan M Schott, Henrik Zetterberg
Alzheimer's research & therapy - 2020 -
Chemical Imaging of Evolving Amyloid Plaque Pathology and Associated Aβ Peptide Aggregation in a Transgenic Mouse Model of Alzheimer's
Disease.
Wojciech Michno, Patrick M. Wehrli, Silvio Meier, Dag Sehlin, Stina Syvänen, Henrik Zetterberg, Kaj Blennow, Jörg Hanrieder
Journal of neurochemistry - 2020 -
Relevance of biomarkers across different
neurodegenerative.
Alexander J Ehrenberg, Ayesha Khatun, Emma Coomans, Matthew J Betts, Federica Capraro, Elisabeth H Thijssen, Konstantin Senkevich, Tehmina Bharucha, Mehrsa Jafarpour, Peter N E Young, William Jagust, Stephen F Carter, Tammaryn Lashley, Lea T Grinberg, Joana B Pereira, Niklas Mattsson-Carlgren, Nicholas J. Ashton, Jörg Hanrieder, Henrik Zetterberg, Michael Schöll, Ross W Paterson
Alzheimer's research & therapy - 2020 -
Computational Analysis of Alzheimer Amyloid Plaque Composition in 2D-and Elastically Reconstructed 3D-MALDI MS
Images
T. Enzlein, J. Cordes, B. Munteanu, Wojciech Michno, L. Serneels, B. De Strooper, Jörg Hanrieder, I. Wolf, L. Chavez-Gutierrez, C. Hopf
Analytical Chemistry - 2020 -
Chemometric Strategies for Sensitive Annotation and Validation of Anatomical Regions of Interest in Complex Imaging Mass Spectrometry
Data.
Patrick M. Wehrli, Wojciech Michno, Kaj Blennow, Henrik Zetterberg, Jörg Hanrieder
Journal of the American Society for Mass Spectrometry - 2019 -
Pyroglutamation of amyloid-βx-42 (Aβx-42) followed by Aβ1-40 deposition underlies plaque polymorphism in progressing Alzheimer's disease
pathology.
Wojciech Michno, Sofie Nyström, Patrick M. Wehrli, Tammaryn Lashley, Gunnar Brinkmalm, Laurent Guerard, Stina Syvänen, Dag Sehlin, Ibrahim Kaya, Dimitri Brinet, K Peter R Nilsson, Per Hammarström, Kaj Blennow, Henrik Zetterberg, Jörg Hanrieder
Journal of Biological Chemistry - 2019 -
Molecular imaging mass spectrometry for probing protein dynamics in neurodegenerative disease
pathology.
Wojciech Michno, Patrick M. Wehrli, Kaj Blennow, Henrik Zetterberg, Jörg Hanrieder
Journal of neurochemistry - 2019 -
Association of PTHrP levels in CSF with Alzheimer's disease
biomarkers
M. M. Kushnir, Wojciech Michno, A. L. Rockwood, Kaj Blennow, F. G. Strathmann, Jörg Hanrieder
Clinical Mass Spectrometry - 2019 -
MALDI imaging mass spectrometry: Neurochemical imaging of proteins and
peptides
Jörg Hanrieder, Henrik Zetterberg, Kaj Blennow
Neuroproteomics. Ka Wan Li (red.) - 2019 -
Amyloid fibril polymorphism and cell-specific toxicity in
vivo
M. Jonson, S. Nystrom, A. Sandberg, M. Carlback, Wojciech Michno, Jörg Hanrieder, A. Starkenberg, K. Peter, R. Nilsson, S. Thor, P. Hammarstrom
Amyloid-Journal of Protein Folding Disorders - 2019 -
GM1 locates to mature amyloid structures implicating a prominent role for glycolipid-protein interactions in Alzheimer
pathology.
Wojciech Michno, Patrick M. Wehrli, Henrik Zetterberg, Kaj Blennow, Jörg Hanrieder
Biochimica et biophysica acta. Proteins and proteomics - 2019 -
Shedding Light on the Molecular Pathology of Amyloid Plaques in Transgenic Alzheimer's Disease Mice Using Multimodal MALDI Imaging Mass
Spectrometry
Ibrahim Kaya, Henrik Zetterberg, Kaj Blennow, Jörg Hanrieder
ACS Chemical Neuroscience - 2018 -
Multimodal Chemical Imaging of Amyloid Plaque Polymorphism Reveals A beta Aggregation Dependent Anionic Lipid Accumulations and
Metabolism
Wojciech Michno, Ibrahim Kaya, S. Nystrom, Laurent Guerard, K. P. R. Nilsson, P. Hammarstrom, Kaj Blennow, Henrik Zetterberg, Jörg Hanrieder
Analytical Chemistry - 2018 -
Aggregated Aβ1-42 Is Selectively Toxic for Neurons, Whereas Glial Cells Produce Mature Fibrils with Low Toxicity in
Drosophila
M. Jonson, S. Nyström, A. Sandberg, M. Carlback, Wojciech Michno, Jörg Hanrieder, A. Starkenberg, K. P. R. Nilsson, S. Thor, P. Hammarström
Cell Chemical Biology - 2018 -
Delineating Amyloid Plaque Associated Neuronal Sphingolipids in Transgenic Alzheimer's Disease Mice (tgArcSwe) Using MALDI Imaging Mass
Spectrometry.
Ibrahim Kaya, Dimitri Brinet, Wojciech Michno, Stina Syvänen, Dag Sehlin, Henrik Zetterberg, Kaj Blennow, Jörg Hanrieder
ACS chemical neuroscience - 2017 -
Novel Trimodal MALDI Imaging Mass Spectrometry (IMS3) at 10 μm Reveals Spatial Lipid and Peptide Correlates Implicated in Aβ Plaque Pathology in Alzheimer's
Disease.
Ibrahim Kaya, Dimitri Brinet, Wojciech Michno, Henrik Zetterberg, Kaj Blennow, Jörg Hanrieder
ACS chemical neuroscience - 2017 -
MALDI imaging delineates hippocampal glycosphingolipid changes associated with neurotoxin induced proteopathy following neonatal BMAA
exposure.
Oskar Karlsson, Wojciech Michno, Yusuf Ransome, Jörg Hanrieder
Biochimica et biophysica acta - 2017 -
Imaging mass spectrometry in drug development and
toxicology.
Oskar Karlsson, Jörg Hanrieder
Archives of toxicology - 2017 -
Histology-Compatible MALDI Mass Spectrometry Based Imaging of Neuronal Lipids for Subsequent Immunofluorescent
Staining.
Ibrahim Kaya, Wojciech Michno, Dimitri Brinet, Yasmine Iacone, Giulia Zanni, Kaj Blennow, Henrik Zetterberg, Jörg Hanrieder
Analytical Chemistry - 2017 -
Lithium Accumulates in Neurogenic Brain Regions as Revealed by High Resolution Ion
Imaging
Giulia Zanni, Wojciech Michno, E. Di Martino, Anna Tjärnlund-Wolf, J. Pettersson, C. E. Mason, G. Hellspong, K. Blomgren, Jörg Hanrieder
Scientific Reports - 2017 -
Probing Amyloid-β Pathology in transgenic Alzheimer's disease (tgArcSwe) mice using MALDI Imaging Mass
Spectrometry
Louise Carlred, Wojciech Michno, Ibrahim Kaya, Peter Sjövall, Stina Syvänen, Jörg Hanrieder
Journal of neurochemistry - 2016 -
Intracellular fibril formation, calcification, and enrichment of chaperones, cytoskeletal, and intermediate filament proteins in the adult hippocampus CA1 following neonatal exposure to the nonprotein amino acid
BMAA
O. Karlsson, A. L. Berg, Jörg Hanrieder, G. Arnerup, A. K. Lindstrom, E. B. Brittebo
Archives of Toxicology - 2015 -
Spatial neuroproteomics using imaging mass
spectrometry
Jörg Hanrieder, Per Malmberg, Andrew G Ewing
Biochimica Et Biophysica Acta-Proteins and Proteomics - 2015 -
Dietary uptake of omega-3 fatty acids in mouse tissue studied by time-of-flight secondary ion mass spectrometry
(TOF-SIMS)
P. Sjovall, M. Rossmeisl, Jörg Hanrieder, O. Kuda, J. Kopecky, M. Bryhn
Analytical and Bioanalytical Chemistry - 2015 -
Spatial Elucidation of Spinal Cord Lipid- and Metabolite-Regulations in Amyotrophic Lateral
Sclerosis
Jörg Hanrieder, Andrew G Ewing
Scientific Reports - 2014 -
High Resolution Metabolite Imaging in the Hippocampus Following Neonatal Exposure to the Environmental Toxin BMAA Using
ToF-SIMS
Jörg Hanrieder, Lorenz Gerber, Åsa P Sandelius, Eva B. Brittebo, Andrew G Ewing, Oskar Karlsson
Acs Chemical Neuroscience - 2014 -
Probing the lipid chemistry of neurotoxin-induced hippocampal lesions using multimodal imaging mass
spectrometry
Jörg Hanrieder, K. Oskar, E. B. Brittebo, Per Malmberg, Andrew G Ewing
Surface and Interface Analysis: 19th International Conference on Secondary Ion Mass Spectrometry (SIMS) - 2014 -
Cerebrospinal fluid proteome analysis reveals differentially abundant proteins in multiple
sclerosis
J. Fuvesi, R. Danielsson, K. Bencsik, Jörg Hanrieder, V. Zsiros, C. Rajda, P. Hakansson, L. Vecsei, J. Bergquist
Multiple Sclerosis Journal - 2014 -
Using imaging ToF-SIMS data to determine the cell wall thickness of fibers in
wood
Lorenz Gerber, V. M. Hoang, L. Tran, H. A. T. Kiet, Per Malmberg, Jörg Hanrieder, Andrew G Ewing
Surface and Interface Analysis: 19th International Conference on Secondary Ion Mass Spectrometry (SIMS) - 2014 -
Comprehensive multiplexed protein quantitation delineates eosinophilic and neutrophilic experimental
asthma
M. Bergquist, S. Jonasson, J. Hjoberg, G. Hedenstierna, Jörg Hanrieder
Bmc Pulmonary Medicine - 2014 -
Capillary Electrophoresis-Mass Spectrometry-Based Detection of Drugs and Neurotransmitters in Drosophila
Brain
Nhu TN Phan, Jörg Hanrieder, Carina Berglund, Andrew G Ewing
Analytical Chemistry - 2013 -
Imaging mass spectrometry in
neuroscience.
Jörg Hanrieder, Nhu TN Phan, Michael E. Kurczy, Andrew G Ewing
ACS chemical neuroscience - 2013 -
Time-of-Flight Secondary Ion Mass Spectrometry Based Molecular Histology of Human Spinal Cord Tissue and Motor
Neurons
Jörg Hanrieder, Per Malmberg, Olle R Lindberg, John S. Fletcher, Andrew G Ewing
Analytical Chemistry - 2013 -
Analysis of neuropeptides by MALDI imaging mass
spectrometry.
Anna Ljungdahl, Jörg Hanrieder, Jonas Bergquist, Malin Andersson
Methods in molecular biology (Clifton, N.J.) - 2013 -
Glycoprotein 130 promotes human blastocyst development in
vitro
F. Hambiliki, Jörg Hanrieder, J. Bergquist, J. Hreinsson, A. Stavreus-Evers, K. Wanggren
Fertility and Sterility - 2013 -
Freeze-Drying as Sample Preparation for Micellar Electrokinetic Capillary Chromatography-Electrochemical Separations of Neurochemicals in Drosophila
Brains
E. C. Berglund, N. J. Kuklinski, E. Karagunduz, Kubra Ucar, Jörg Hanrieder, Andrew G Ewing
Analytical Chemistry - 2013 -
MALDI imaging of post-mortem human spinal cord in amyotrophic lateral
sclerosis
Jörg Hanrieder, T. Ekegren, M. Andersson, J. Bergquist
Journal of Neurochemistry - 2013 -
Proteins in aqueous humor from cataract patients with and without pseudoexfoliation
syndrome.
Amelie Botling Taube, Emilia Hardenborg, Magnus Wetterhall, Konstantin Artemenko, Jörg Hanrieder, Marit Andersson, Albert Alm, Jonas Bergquist
European journal of mass spectrometry (Chichester, England) - 2012 -
Neonatal exposure to the cyanobacterial toxin BMAA induces changes in protein expression and neurodegeneration in adult
hippocampus.
Oskar Karlsson, Anna-Lena Berg, Anna-Karin Lindström, Jörg Hanrieder, Gunnel Arnerup, Erika Roman, Jonas Bergquist, Nils Gunnar Lindquist, Eva B Brittebo, Malin Andersson
Toxicological sciences : an official journal of the Society of Toxicology - 2012 -
MALDI imaging mass spectrometry of neuropeptides in Parkinson's
disease
Jörg Hanrieder, A. Ljungdahl, M.A. Andersson
Journal of Visualized Experiments - 2012 -
Proteomic Analysis of Cerebrospinal Fluid in a Fulminant Case of Multiple
Sclerosis
J. Fuvesi, Jörg Hanrieder, K. Bencsik, C. Rajda, S. K. Kovacs, L. Kaizer, S. Beniczky, L. Vecsei, J. Bergquist
International Journal of Molecular Sciences - 2012 -
MALDI mass spectrometry based molecular phenotyping of CNS glial cells for prediction in mammalian brain
tissue.
Jörg Hanrieder, Grzegorz Wicher, Jonas Bergquist, Malin Andersson, Asa Fex-Svenningsen
Analytical and bioanalytical chemistry - 2011 -
L-DOPA-induced dyskinesia is associated with regional increase of striatal dynorphin peptides as elucidated by imaging mass
spectrometry.
Jörg Hanrieder, Anna Ljungdahl, Maria Fälth, Sofie Eriksson Mammo, Jonas Bergquist, Malin Andersson
Molecular & cellular proteomics : MCP - 2011 -
Imaging mass spectrometry reveals elevated nigral levels of dynorphin neuropeptides in L-DOPA-induced dyskinesia in rat model of Parkinson's
disease.
Anna Ljungdahl, Jörg Hanrieder, Maria Fälth, Jonas Bergquist, Malin Andersson
PloS one - 2011 -
Assessment of the partitioning capacity of high abundant proteins in human cerebrospinal fluid using affinity and immunoaffinity subtraction spin
columns.
Magnus Wetterhall, Aida Zuberovic, Jörg Hanrieder, Jonas Bergquist
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences - 2010 -
Development of affinity columns for the removal of high-abundance proteins in cerebrospinal
fluid.
Margareta Ramström, Aida Zuberovic, Caroline Grönwall, Jörg Hanrieder, Jonas Bergquist, Sophia Hober
Biotechnology and applied biochemistry - 2009 -
Surface modified capillary electrophoresis combined with in solution isoelectric focusing and MALDI-TOF/TOF MS: a gel-free multidimensional electrophoresis approach for proteomic profiling--exemplified on human follicular
fluid.
Jörg Hanrieder, Aida Zuberovic, Jonas Bergquist
Journal of chromatography. A - 2009 -
Protein content in aqueous humor from patients with pseudoexfoliation (PEX) investigated by capillary LC MALDI-TOF/TOF
MS.
Emilia Hardenborg, Amelie Botling-Taube, Jörg Hanrieder, Marit Andersson, Albert Alm, Jonas Bergquist
Proteomics. Clinical applications - 2009 -
Temporally resolved differential proteomic analysis of human ventricular CSF for monitoring traumatic brain injury biomarker
candidates.
Jörg Hanrieder, Magnus Wetterhall, Per Enblad, Lars Hillered, Jonas Bergquist
Journal of neuroscience methods - 2009 -
CE MALDI-TOF/TOF MS for multiplexed quantification of proteins in human ventricular cerebrospinal
fluid.
Aida Zuberovic, Magnus Wetterhall, Jörg Hanrieder, Jonas Bergquist
Electrophoresis - 2009 -
Proteomic analysis of human follicular fluid using an alternative bottom-up
approach.
Jörg Hanrieder, Adrien Nyakas, Tord Naessén, Jonas Bergquist
Journal of proteome research - 2008 -
Clinical perspectives of high-resolution mass spectrometry-based proteomics in neuroscience: exemplified in amyotrophic lateral sclerosis biomarker discovery
research.
Titti Ekegren, Jörg Hanrieder, Jonas Bergquist
Journal of mass spectrometry : JMS - 2008 -
Proteome profiling of human cerebrospinal fluid: exploring the potential of capillary electrophoresis with surface modified capillaries for analysis of complex biological
samples.
Aida Zuberovic, Jörg Hanrieder, Ulf Hellman, Jonas Bergquist, Magnus Wetterhall
European journal of mass spectrometry (Chichester, England) - 2008 -
Proteomic characterization of IgY preparations purified with a water dilution
method.
Elin Nilsson, Jörg Hanrieder, Jonas Bergquist, Anders Larsson
Journal of agricultural and food chemistry - 2008 -
Expression and purification of catalytically active human PHD3 in Escherichia
coli.
Natalia Fedulova, Jörg Hanrieder, Jonas Bergquist, Lars O Emrén
Protein expression and purification - 2007 -
Focused proteomics in post-mortem human spinal
cord.
Titti Ekegren, Jörg Hanrieder, Sten-Magnus Aquilonius, Jonas Bergquist
Journal of proteome research - 2006 -
Designer antibacterial peptides kill fluoroquinolone-resistant clinical
isolates.
Laszlo Otvos, John D Wade, Feng Lin, Barry A Condie, Jörg Hanrieder, Ralf Hoffmann
Journal of medicinal chemistry - 2005