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Doktorandseminarium Fysik: Jesús Pineda

Naturvetenskap & IT

Fysikdoktorandernas seminarieserie hålls via Zoom. En doktorand per tillfälle ger en 15-minuterspresentation om sitt arbete, följt av frågor. Presentationerna riktar sig till fysikintresserade från alla inriktningar.

Seminarium
Datum
30 aug 2021
Tid
12:00 - 12:30
Plats
Zoom
Ytterligare information
Zoom-länk

Zoom-länk: https://gu-se.zoom.us/j/6314424991

Title: Quantitative biological analysis of brightfield cell images using deep learning

Abstract

Quantitative analysis of cell structures is essential for pharmaceutical drug screening and medical diagnostics. This presentation introduces a deep-learning-powered approach to extract quantitative biological information from brightfield microscopy images. Specifically, we train a conditional generative adversarial neural network (cGAN) to virtually stain lipid droplets, cytoplasm, and nuclei from brightfield images of human adipocytes, which are of particular interest for nanomedicine and vaccine development. Subsequently, we demonstrate that these virtually-stained images can be successfully employed to extract quantitative biologically relevant measures in a downstream cell-profiling analysis.  

Link to the paper: https://aip.scitation.org/doi/10.1063/5.0044782

Bio

I am a PhD student in the Soft Matter Lab group, supervised by Giovanni Volpe. My research interests include Deep learning, Biophysics, and Biomedical image processing.