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Dorota Raj
Postdoctor
Department of SurgeryAbout Dorota Raj
Dorota Raj defended her thesis in subject area of surgery, December 3, 2021
The title of her thesis is - Signaling pathways and novel genetic factors involved in modulation of cisplatin response in C. elegans
Read a short populär science summery about the thesis - Modeling of cisplatin resistance in C. elegans, to improve cisplatin cancer therapy
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Ageing promotes metastasis via activation of the integrated stress
response.
Angana Patel, Jozefina Dzanan, Kevin Ali, Ella Äng, Samantha W Alvarez, Dorota Raj, Martin Dankis, Ilayda Altinönder, Maria Schwarz, Kristell Le Gal Beneroso, Emre Bedel, Ahmed Ezat El Zowalaty, Emma Jonasson, Heba Albatrok, Nadia Gul, Jozef P. Bossowski, Ray Pillai, Patrick Micke, Johan Botling, Levent Akyürek, Davide Angeletti, Sama Sayin, Anetta Härtlova, Thales Papagiannakopoulos, Roger Olofsson Bagge, Anders Ståhlberg, Andreas Hallqvist, Clotilde Wiel, Volkan Sayin
Nature - 2026 -
Identification of a BACH1 lung cancer signature: A novel tool for understanding BACH1 biology and identifying new
inhibitors
Donika Klenja-Skudrinja, Kevin Ali, David Walker, Maureen Higgins, Angana Patel, Dorota Raj, Anna Creelman, Charlotte Mcdowall, Conor Taylor, Tomasz Wenta, Erik Larsson, Clotilde Wiel, Volkan Sayin, Laureano de la Vega
REDOX BIOLOGY - 2025 -
A proinsulin-dependent interaction between ENPL-1 and ASNA-1 in neurons is required to maintain insulin secretion in C.
elegans.
Agnieszka Podraza-Farhanieh, Dorota Raj, Gautam Kao, Peter Naredi
Development (Cambridge, England) - 2023 -
Cisplatin toxicity is counteracted by the activation of the p38/ATF-7 signaling pathway in post-mitotic C.
elegans
Dorota Raj, Bashar Kraish, Jari Martikainen, Agnieszka Podraza-Farhanieh, Gautam Kao, Peter Naredi
Nature Communications - 2023 -
Identification of C. elegans ASNA-1 domains and tissue requirements that differentially influence platinum sensitivity and growth
control.
Dorota Raj, Agnieszka Podraza-Farhanieh, Pablo Gallego, Gautam Kao, Peter Naredi
PLoS genetics - 2022 -
Alternative redox forms of ASNA-1 separate insulin signaling from tail-anchored protein targeting and cisplatin resistance in C.
elegans
Dorota Raj, O. Billing, Agnieszka Podraza-Farhanieh, Bashar Kraish, O. Hemmingsson, Gautam Kao, Peter Naredi
Scientific Reports - 2021 -
Signaling pathways and novel genetic factors involved in modulation of cisplatin response in C.
elegans
Dorota Raj
2021 -
ENPL-1, the Caenorhabditis elegans homolog of GRP94, promotes insulin secretion via regulation of proinsulin processing and
maturation
Agnieszka Podraza, Balasubramanian Natarajan, Dorota Raj, Gautam Kao, Peter Naredi
Development - 2020