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- Cecilia Lässer
Cecilia Lässer
Researcher
Department of Internal Medicine and Clinical-
Heat inactivation of foetal bovine serum performed after EV-depletion influences the proteome of cell-derived extracellular
vesicles
Ornella Urzi, Markus Bergqvist, Cecilia Lässer, Marta Moschetti, Junko Johansson, Daniele D'Arrigo, Roger Olofsson Bagge, Rossella Crescitelli
JOURNAL OF EXTRACELLULAR VESICLES - 2024 -
Extracellular vesicle
analysis
A. Hendrix, L. Lippens, C. Pinheiro, C. Thery, L. Martin-Jaular, Jan Lötvall, Cecilia Lässer, A. F. Hill, K. W. Witwer
Nature Reviews Methods Primers - 2023 -
Exogenous female sex steroid hormones and new-onset asthma in women: a matched case-control
study
Guo-Qiang Zhang, Rani Basna, Maya B Mathur, Cecilia Lässer, Roxana Mincheva, Linda Ekerljung, Göran Wennergren, Madeleine Rådinger, Bo Lundbäck, Hannu Kankaanranta, Bright I Nwaru
BMC medicine - 2023 -
Detoxified synthetic bacterial membrane vesicles as a vaccine platform against bacteria and
SARS-CoV-2
Kyong-Su Park, Kristina Svennerholm, Rossella Crescitelli, Cecilia Lässer, Inta Gribonika, Mickael Andersson, Jonas Boström, Hanna Alalam, Ali M Harandi, Anne Farewell, Jan Lötvall
Journal of Nanobiotechnology - 2023 -
MIBlood-EV: Minimal information to enhance the quality and reproducibility of blood extracellular vesicle
research
Fabrice Lucien, Dakota Gustafson, Metka Lenassi, Bo Li, Jacob J. Teske, Eric Boilard, Katharina Clemm von Hohenberg, Juan Manual Falcón-Perez, Alice Gualerzi, Antonia Reale, Jennifer C. Jones, Cecilia Lässer, Charlotte Lawson, Irina Nazarenko, Lorraine O'Driscoll, Ryan Pink, Pia R.M. Siljander, Carolina Soekmadji, An Hendrix, Joshua A. Welsh, Kenneth W. Witwer, Rienk Nieuwland
Journal of Extracellular Vesicles - 2023 -
Quantitative Proteomics Identifies Proteins Enriched in Large and Small Extracellular
Vesicles
Anna Lischnig, Markus Bergqvist, T. Ochiya, Cecilia Lässer
Molecular & Cellular Proteomics - 2022 -
Extracellular vesicle DNA from human melanoma tissues contains cancer-specific
mutations
Rossella Crescitelli, Stefan Filges, Nasibeh Karimi, Ornella Urzi, Tamara Alonso Agudo, Anders Ståhlberg, Jan Lötvall, Cecilia Lässer, Roger Olofsson Bagge
Frontiers in Cell and Developmental Biology - 2022 -
Targeting Myd88 using peptide-loaded mesenchymal stem cell membrane-derived synthetic vesicles to treat systemic
inflammation
Kyong-Su Park, Markus Bergqvist, Cecilia Lässer, Jan Lötvall
Journal of Nanobiotechnology - 2022 -
Characterization of surface markers on extracellular vesicles isolated from lymphatic exudate from patients with breast
cancer
Karin Ekström, Rossella Crescitelli, Hafsteinn Ingi Pétursson, Junko Johansson, Cecilia Lässer, Roger Olofsson Bagge
Bmc Cancer - 2022 -
Immune-Associated Proteins Are Enriched in Lung Tissue-Derived Extracellular Vesicles during Allergen-Induced Eosinophilic Airway
Inflammation
Cecilia Lässer, Yasunari Kishino, Kyong-Su Park, Ganesh V Shelke, Nasibeh Karimi, Shintaro Suzuki, Lilit Hovhannisyan, Madeleine Rådinger, Jan Lötvall
International Journal of Molecular Sciences - 2021 -
Isolation and characterization of extracellular vesicle subpopulations from
tissues.
Rossella Crescitelli, Cecilia Lässer, Jan Lötvall
Nature protocols - 2021 -
Menopausal hormone therapy and women's health: An umbrella
review
Guo-Qiang Zhang, J. L. Chen, Y. Luo, M. B. Mathur, P. Anagnostis, U. Nurmatov, M. Talibov, J. Zhang, C. M. Hawrylowicz, M. A. Lumsden, H. Critchley, A. Sheikh, Bo Lundbäck, Cecilia Lässer, H. Kankaanranta, S. H. Lee, Bright I Nwaru
PLoS Medicine - 2021 -
Synthetic bacterial vesicles combined with tumour extracellular vesicles as cancer
immunotherapy
Kyong-Su Park, Kristina Svennerholm, Rossella Crescitelli, Cecilia Lässer, Inta Gribonika, Jan Lötvall
Journal of Extracellular Vesicles - 2021 -
Extracellular vesicles from mast cells induce mesenchymal transition in airway epithelial
cells
Yanan Yin, Ganesh V Shelke, Cecilia Lässer, H. Brismar, Jan Lötvall
Respiratory research - 2020 -
Subpopulations of extracellular vesicles from human metastatic melanoma tissue identified by quantitative proteomics after optimized
isolation
Rossella Crescitelli, Cecilia Lässer, Su Chul Jang, Aleksander Cvjetkovic, Carina Malmhäll, Nasibeh Karimi, Johanna L Höög, Iva Johansson, Johannes Fuchs, Annika Thorsell, Y. S. Gho, Roger Olofsson Bagge, Jan Lötvall
Journal of Extracellular Vesicles - 2020 -
Blood extracellular vesicles from healthy individuals regulate hematopoietic stem cells as humans
age
I. Grenier-Pleau, K. Tyryshkin, T. D. Le, J. Rudan, E. Bonneil, P. Thibault, K. R. Zeng, Cecilia Lässer, D. Mallinson, D. Lamprou, J. L. Hui, L. M. Postovit, E. Y. W. Chan, S. A. Abraham
Aging Cell - 2020 -
T2 and T17 cytokines alter the cargo and function of airway epithelium-derived extracellular
vesicles
Elisabeth Ax, Z. Jevnikar, Aleksander Cvjetkovic, Carina Malmhäll, H. Olsson, Madeleine Rådinger, Cecilia Lässer
Respiratory Research - 2020 -
Isolation and characterization of microvesicles from mesenchymal stem
cells.
M Rezaa Mohammadi, Milad Riazifar, Egest J Pone, Ashish Yeri, Kendall Van Keuren-Jensen, Cecilia Lässer, Jan Lötvall, Weian Zhao
Methods - 2020 -
Endosomal signalling via exosome surface TGF
beta-1
Ganesh V Shelke, Yanan Yin, Su Chul Jang, Cecilia Lässer, S. Wennmalm, H. J. Hoffmann, L. Li, Y. S. Gho, Jonas A Nilsson, Jan Lötvall
Journal of Extracellular Vesicles - 2019 -
Stem Cell-Derived Exosomes as Nanotherapeutics for Autoimmune and Neurodegenerative
Disorders
M. Riazifar, M. R. Mohammadi, E. J. Pone, A. Yeri, Cecilia Lässer, A. I. Segaliny, L. L. McIntyre, Ganesh V Shelke, E. Hutchins, A. Hamamoto, E. N. Calle, Rossella Crescitelli, W. Liao, V. Pham, Y. Yin, J. Jayaraman, J. R. T. Lakey, C. M. Walsh, K. Van Keuren-Jensen, Jan Lötvall, W. Zhao
ACS Nano - 2019 -
Mapping Extracellular RNA Sheds Lights on Distinct
Carriers
Cecilia Lässer
Cell - 2019 -
Mesenchymal stromal cell-derived nanovesicles ameliorate bacterial outer membrane vesicle-induced sepsis via
IL-10.
Kyong-Su Park, Kristina Svennerholm, Ganesh V Shelke, Elga Bandeira, Cecilia Lässer, Su Chul Jang, Rakesh Chandode, Inta Gribonika, Jan Lötvall
Stem cell research & therapy - 2019 -
DNA analysis of low- and high-density fractions defines heterogeneous subpopulations of small extracellular vesicles based on their DNA cargo and
topology
Elisa Lázaro-Ibáñez, Cecilia Lässer, Ganesh V Shelke, Rossella Crescitelli, Su Chul Jang, Aleksander Cvjetkovic, Anaís García-Rodríguez, Jan Lötvall
Journal of Extracellular Vesicles - 2019 -
Considerations towards a roadmap for collection, handling and storage of blood extracellular
vesicles
A. Clayton, E. Boilard, E. I. Buzas, L. Cheng, J. M. Falcon-Perez, C. Gardiner, D. Gustafson, A. Gualerzi, A. Hendrix, A. Hoffmann, J. Jones, Cecilia Lässer, C. Lawson, M. Lenassi, I. Nazarenko, L. O'Driscoll, R. Pink, P. R. M. Siljander, C. Soekmadji, M. Wauben, J. A. Welsh, K. Witwer, L. Zheng, R. Nieuwland
Journal of Extracellular Vesicles - 2019 -
Enhancement of therapeutic potential of mesenchymal stem cell-derived extracellular
vesicles
Kyong-Su Park, Elga Bandeira, Ganesh V Shelke, Cecilia Lässer, Jan Lötvall
Stem Cell Research & Therapy - 2019 -
Subpopulations of extracellular vesicles and their therapeutic
potential
Cecilia Lässer, Su Chul Jang, Jan Lötvall
Molecular Aspects of Medicine - 2018 -
Detailed analysis of the plasma extracellular vesicle proteome after separation from
lipoproteins
Nasibeh Karimi, Aleksander Cvjetkovic, Su Chul Jang, Rossella Crescitelli, M. A. H. Feizi, R. Nieuwland, Jan Lötvall, Cecilia Lässer
Cellular and Molecular Life Sciences - 2018 -
Krefting Research Centre: Astma och allergi från epidemiologi till
lab
Jan Lötvall, Bo Lundbäck, Göran Wennergren, Bright I Nwaru, Linda Ekerljung, Cecilia Lässer, Madeleine Rådinger
Lung & Allergiforum - 2018 -
Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014
guidelines
C. Thery, K. W. Witwer, E. Aikawa, A. P. D. Rubio, Karin Ekström, Ganesh V Shelke, Maugeri Marco, Muhammad Nawaz, Rossella Crescitelli, Cecilia Lässer, Jan Lötvall, Jessica Wahlgren
Journal of Extracellular Vesicles - 2018 -
Summary of the ISEV workshop on extracellular vesicles as disease biomarkers, held in Birmingham, UK, during December
2017
Aled Clayton, Dominik Buschmann, J. Brian Byrd, David R.F. Carter, Lesley Cheng, Carolyn Compton, George Daaboul, Andrew Devitt, Juan Manuel Falcon-Perez, Chris Gardiner, Dakota Gustafson, Paul Harrison, Clemens Helmbrecht, An Hendrix, Andrew Hill, Andrew Hoffman, Jennifer C. Jones, Raghu Kalluri, Ji Yoon Kang, Benedikt Kirchner, Cecilia Lässer, Charlotte Lawson, Metka Lenassi, Carina Levin, Alicia Llorente, Elena S. Martens-Uzunova, Andreas Möller, Luca Musante, Takahiro Ochiya, Ryan C. Pink, Hidetoshi Tahara, Marca H.M. Wauben, Jason P. Webber, Joshua A. Welsh, Kenneth W. Witwer, Hang Yin, Rienk Nieuwland
Journal of Extracellular Vesicles - 2018 -
Is the DNA of placental origin packaged in exosomes isolated from plasma and serum of pregnant
women?
Gabriela Repiská, Barbora Konečná, Ganesh V Shelke, Cecilia Lässer, Barbora Izrael Vlková, Gabriel Minárik
Clinical chemistry and laboratory medicine - 2018 -
Obstacles and opportunities in the functional analysis of extracellular vesicle RNA - An ISEV position
paper
B. Mateescu, E. J. K. Kowal, B. W. M. van Balkom, S. Bartel, S. N. Bhattacharyya, E. I. Buzás, A. H. Buck, P. de Candia, F. W. N. Chow, S. Das, T. A. P. Driedonks, Cecilia Lässer
Journal of Extracellular Vesicles - 2017 -
Escherichia coli outer membrane vesicles can contribute to sepsis induced cardiac
dysfunction.
Kristina Svennerholm, Kyong-Su Park, Johannes Wikström, Cecilia Lässer, Rossella Crescitelli, Ganesh V Shelke, Su Chul Jang, Shintaro Suzuki, Elga Bandeira, Charlotta S Olofsson, Jan Lötvall
Scientific reports - 2017 -
Exosomes purified from a single cell type have diverse
morphology
Davide Zabeo, Aleksander Cvjetkovic, Cecilia Lässer, Martin Schorb, Jan Lötvall, Johanna L Höög
Journal of extracellular vesicles - 2017 -
BRAF(V600) inhibition alters the microRNA cargo in the vesicular secretome of malignant melanoma
cells
Taral R Lunavat, L. Cheng, Berglind Osk Einarsdottir, Roger Olofsson Bagge, Somsundar Veppil Muralidharan, R. A. Sharples, Cecilia Lässer, Y. S. Gho, A. F. Hill, Jonas A Nilsson, Jan Lötvall
Proceedings of the National Academy of Sciences of the United States of America - 2017 -
Extracellular vesicles in
motion
Aleksander Cvjetkovic, Rossella Crescitelli, Cecilia Lässer, Davide Zabeo, Per O Widlund, Thomas Nyström, Johanna L Höög, Jan Lötvall
Science Matters - 2017 -
Two distinct extracellular RNA signatures released by a single cell type identified by microarray and next-generation
sequencing.
Cecilia Lässer, Ganesh V Shelke, Ashish Yeri, Dae-Kyum Kim, Rossella Crescitelli, Stefania Raimondo, Margareta Sjöstrand, Yong Song Gho, Kendall Van Keuren Jensen, Jan Lötvall
RNA biology - 2017 -
Methods for the physical characterization and quantification of extracellular vesicles in biological
samples
Déborah L. M. Rupert, Virginia Claudio, Cecilia Lässer, Marta Bally
Biochimica et Biophysica Acta - General Subjects - 2017 -
Exosomes in the nose induce immune cell trafficking and harbour an altered protein cargo in chronic airway
inflammation.
Cecilia Lässer, Serena O'Neil, Ganesh V Shelke, Carina Sihlbom, Sara Folkesson Hansson, Yong Song Gho, Bo Lundbäck, Jan Lötvall
Journal of Translational Medicine - 2016 -
Dual-Wavelength Surface Plasmon Resonance for Determining the Size and Concentration of Sub-Populations of Extracellular
Vesicles
Déborah L. M. Rupert, Ganesh V Shelke, Gustav Emilsson, Virginia Claudio, Stephan Block, Cecilia Lässer, Andreas Dahlin, Jan Lötvall, Marta Bally, Vladimir P. Zhdanov, Fredrik Höök
Analytical Chemistry - 2016 -
RNAi delivery by exosome-mimetic nanovesicles - Implications for targeting c-Myc in
cancer
Taral R Lunavat, Su Chul Jang, Lisa M Nilsson, Hyun Taek Park, Gabriela Repiska, Cecilia Lässer, Jonas A Nilsson, Yong Song Gho, Jan Lötvall
Biomaterials - 2016 -
The International Society for Extracellular Vesicles launches the first massive open online course on extracellular
vesicles.
Cecilia Lässer, Clotilde Théry, Edit I Buzás, Suresh Mathivanan, Weian Zhao, Yong Song Gho, Jan Lötvall
Journal of extracellular vesicles - 2016 -
Detailed Analysis of Protein Topology of Extracellular Vesicles–Evidence of Unconventional Membrane Protein
Orientation
Aleksander Cvjetkovic, Su Chul Jang, Barbora Konečná, Johanna L Höög, Carina Sihlbom, Cecilia Lässer, Jan Lötvall
Scientific Reports - 2016 -
Small RNA deep sequencing discriminates subsets of extracellular vesicles released by melanoma cells - evidence of unique microRNA
cargos.
Taral R Lunavat, Lesley Cheng, Dae-Kyum Kim, Joydeep Bhadury, Su Chul Jang, Cecilia Lässer, Robyn A Sharples, Marcela Davila Lopez, Jonas A Nilsson, Yong Song Gho, Andrew F Hill, Jan Lötvall
RNA biology - 2015 -
EVpedia: A Community Web Portal for Extracellular Vesicles
Research
Dae-Kyum Kim, Jaewook Lee, Sae Rom Kim, Dong-Sic Choi, Yae Jin Yoon, Ji Hyun Kim, Gyeongyun Go, Dinh Nhung, Kahye Hong, Su Chul Jang, Si-Hyun Kim, Kyong-Su Park, Oh Youn Kim, Hyun Taek Park, Ji Hye Seo, Elena Aikawa, Monika Baj-Krzyworzeka, Bas W. M. van Balkom, Mattias Belting, Lionel Blanc, Vincent Bond, Antonella Bongiovanni, Francesc E. Borràs, Luc Buée, Edit I. Buzás, Lesley Cheng, Aled Clayton, Emanuele Cocucci, Charles S. Dela Cruz, Dominic M. Desiderio, Dolores Di Vizio, Karin Ekström, Juan M. Falcon-Perez, Chris Gardiner, Bernd Giebel, David W. Greening, Julia Christina Gross, Dwijendra Gupta, An Hendrix, Andrew F. Hill, Michelle M. Hill, Esther Nolte-'t Hoen, Do Won Hwang, Jameel Inal, Medicharla V. Jagannadham, Muthuvel Jayachandran, Young-Koo Jee, Malene Jørgensen, Kwang Pyo Kim, Yoon-Keun Kim, Thomas Kislinger, Cecilia Lässer, Dong Soo Lee, Hakmo Lee, Johannes van Leeuwen, Thomas Lener, Ming-Lin Liu, Jan Lötvall, Antonio Marcilla, Suresh Mathivanan, Andreas Möller, Jess Morhayim, François Mullier, Irina Nazarenko, Rienk Nieuwland, Diana N. Nunes, Ken Pang, Jaesung Park, Tushar Patel, Gabriella Pocsfalvi, Hernando del Portillo, Ulrich Putz, Marcel I. Ramirez, Marcio L. Rodrigues, Tae-Young Roh, Felix Royo, Susmita Sahoo, Raymond Schiffelers, Shivani Sharma, Pia Siljander, Richard J. Simpson, Carolina Soekmadji, Philip Stahl, Allan Stensballe, Ewa Stępień, Hidetoshi Tahara, Arne Trummer, Hadi Valadi, Laura J. Vella, Sun Nyunt Wai, Kenneth Witwer, María Yáñez-Mó, Hyewon Youn, Reinhard Zeidler, Yong Song Gho
Bioinformatics - 2015 -
Biological properties of extracellular vesicles and their physiological
functions.
María Yáñez-Mó, Pia R-M Siljander, Zoraida Andreu, Apolonija Bedina Zavec, Francesc E Borràs, Edit I Buzas, Krisztina Buzas, Enriqueta Casal, Francesco Cappello, Joana Carvalho, Eva Colás, Anabela Cordeiro-da Silva, Stefano Fais, Juan M Falcon-Perez, Irene M Ghobrial, Bernd Giebel, Mario Gimona, Michael Graner, Ihsan Gursel, Mayda Gursel, Niels H H Heegaard, An Hendrix, Peter Kierulf, Katsutoshi Kokubun, Maja Kosanovic, Veronika Kralj-Iglic, Eva-Maria Krämer-Albers, Saara Laitinen, Cecilia Lässer, Thomas Lener, Erzsébet Ligeti, Aija Linē, Georg Lipps, Alicia Llorente, Jan Lötvall, Mateja Manček-Keber, Antonio Marcilla, Maria Mittelbrunn, Irina Nazarenko, Esther N M Nolte-'t Hoen, Tuula A Nyman, Lorraine O'Driscoll, Mireia Olivan, Carla Oliveira, Éva Pállinger, Hernando A Del Portillo, Jaume Reventós, Marina Rigau, Eva Rohde, Marei Sammar, Francisco Sánchez-Madrid, N Santarém, Katharina Schallmoser, Marie Stampe Ostenfeld, Willem Stoorvogel, Roman Stukelj, Susanne G Van der Grein, M Helena Vasconcelos, Marca H M Wauben, Olivier De Wever
Journal of extracellular vesicles - 2015 -
Exosomes in diagnostic and therapeutic applications: biomarker, vaccine and RNA interference delivery
vehicle
Cecilia Lässer
Expert Opinion on Biological Therapy - 2015 -
Mast cell exosomes promote lung adenocarcinoma cell proliferation - role of KIT-stem cell factor
signaling
Xiao Hui, Cecilia Lässer, Ganesh V Shelke, Juan Wang, Madeleine Rådinger, Taral R Lunavat, Carina Malmhäll, Lihui Lin, Jia Lin, Li Li, Jan Lötvall
Cell Communication and Signaling - 2014 -
Importance of exosome depletion protocols to eliminate functional and RNA-containing extracellular vesicles from fetal bovine
serum
Ganesh V Shelke, Cecilia Lässer, Yong Song Gho, Jan Lötvall
Journal of Extracellular Vesicles - 2014 -
MicroRNA in exosomes isolated directly from the liver circulation in patients with metastatic uveal
melanoma
Maria Eldh, Roger Olofsson Bagge, Cecilia Lässer, Joar Svanvik, Margareta Sjöstrand, Jan Mattsson, Per Lindnér, Dong-Sic Choi, Yong Song Gho, Jan Lötvall
BMC Cancer - 2014 -
Determination of exosome concentration in solution using surface plasmon resonance
spectroscopy.
Deborah LM Rupert, Cecilia Lässer, Maria Eldh, Stephan Block, Vladimir P. Zhdanov, Jan Lötvall, Marta Bally, Fredrik Höök
Analytical Chemistry - 2014 -
The influence of rotor type and centrifugation time on the yield and purity of extracellular
vesicles.
Aleksander Cvjetkovic, Jan Lötvall, Cecilia Lässer
Journal of Extracellular Vesicles - 2014 -
Toxoplasma gondii infection of fibroblasts causes the production of exosome-like vesicles containing a unique array of mRNA and miRNA transcripts compared to serum
starvation
Samuel M Pope, Cecilia Lässer
Journal of Extracellular Vesicles - 2013 -
Distinct RNA profiles in subpopulations of extracellular vesicles: apoptotic bodies, microvesicles and
exosomes.
Rossella Crescitelli, Cecilia Lässer, Tamas G Szabó, Agnes Kittel, Maria Eldh, Irma Dianzani, Edit I Buzás, Jan Lötvall
Journal of extracellular vesicles - 2013 -
Identification and analysis of circulating exosomal microRNA in human body
fluids
Cecilia Lässer
Circulating microRNAs: Methods and Protocols / Kosaka, Nobuyoshi (Ed.) - 2013 -
Exosomes - characterisation of the RNA and protein
cargo
Cecilia Lässer
2013 -
Standardization of sample collection, isolation and analysis methods in extracellular vesicle
research
Kenneth Witwer, Edit Buzás, Lynne Bemis, Adriana Bora, Cecilia Lässer, Jan Lötvall, Esther Nolte-´t Hoen, Melissa Piper, Sarada Sivaraman, Johan Skog, Clotilde Théry, Marca Wauben, Fred Hochberg
Journal of Extracellular Vesicles - 2013 -
The Role of Exosomal Shuttle RNA (esRNA) in Cell-to-Cell
Communication
Cecilia Lässer, Maria Eldh, Jan Lötvall
Emerging Concepts of Tumor Exosome–Mediated Cell-Cell Communication - 2013 -
Exosomal RNA as biomarkers and the therapeutic potential of exosome
vectors.
Cecilia Lässer
Expert Opinion on Biological Therapy - 2012 -
Isolation and characterization of RNA-containing
exosomes.
Cecilia Lässer, Maria Eldh, Jan Lötvall
Journal of Visualized Experiments (JoVE) - 2012 -
Human saliva, plasma and breast milk exosomes contain RNA: uptake by
macrophages.
Cecilia Lässer, Vesta Seyed Alikhani, Karin Ekström, Maria Eldh, Patricia Torregrosa Paredes, Apostolos Bossios, Margareta Sjöstrand, Susanne Gabrielsson, Jan Lötvall, Hadi Valadi
Journal of Translational Medicine - 2011 -
RNA-containing exosomes in human nasal
secretions.
Cecilia Lässer, Serena O'Neil, Linda Ekerljung, Karin Ekström, Margareta Sjöstrand, Jan Lötvall
American journal of rhinology & allergy - 2011