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Charlotta Olofsson
Research Advisor
Sahlgrenska AcademyAbout Charlotta Olofsson
Research group
The regulation of adiponectin secretion in white adipocytes - in metabolic health and disease
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Comparing lipid remodeling of brown adipose tissue, white adipose tissue, and liver after one-week high fat diet intervention with quantitative Raman
microscopy
A. Paul, Belén Chanclón, Cecilia Brännmark, P. Wittung-Stafshede, Charlotta S Olofsson, Ingrid Wernstedt Asterholm, S. H. Parekh
Journal of Cellular Biochemistry - 2023 -
Cardiac Plin5 interacts with SERCA2 and promotes calcium handling and cardiomyocyte
contractility
Mathieu Cinato, Ismena Mardani, Azra Miljanovic, Christina Drevinge, Marion Laudette, Entela Bollano, Marcus Henricsson, Johan Tolö, Marco Bauzá-Thorbrügge, Max Levin, Malin Lindbom, M. Arif, P. Pacher, Linda Andersson, Charlotta S Olofsson, Jan Borén, Malin Levin
Life Science Alliance - 2023 -
A comprehensive mechanistic model of adipocyte signaling with layers of
confidence
W. Loevfors, R. Magnusson, C. Joensson, M. Gustafsson, Charlotta S Olofsson, G. Cedersund, E. Nyman
npj Systems Biology and Applications - 2023 -
Adipocyte-specific ablation of the Ca2+ pump SERCA2 impairs whole-body metabolic function and reveals the diverse metabolic flexibility of white and brown adipose
tissue.
Marco Bauzá-Thorbrügge, Elin Banke, Belén Chanclón, Eduard Peris, Yanling Wu, Musovic Saliha, Cecilia Jönsson, Peter Strålfors, Patrik Rorsman, Charlotta S Olofsson, Ingrid Wernstedt Asterholm
Molecular metabolism - 2022 -
Noradrenaline and ATP regulate adiponectin exocytosis in white adipocytes: Disturbed adrenergic and purinergic signalling in obese and insulin-resistant
mice
Musovic Saliha, Ali Komai, Marina Kalds Said, Man Mohan Shrestha, Yanling Wu, Ingrid Wernstedt Asterholm, Charlotta S Olofsson
Molecular and Cellular Endocrinology - 2022 -
Hindbrain insulin controls feeding
behavior
Kim Eerola, Francesco Longo, Thomas Reinbothe, Jennifer E. Richard, Olesya Shevchouk, Lorena Lopez-Ferreras, Devesh Mishra, Mohammed Asker, Johan Tolö, Caroline Miranda, Musovic Saliha, Charlotta S Olofsson, Patrik Rorsman, Karolina P Skibicka
Molecular Metabolism - 2022 -
Resistin is co-secreted with adiponectin in white mouse
adipocytes
Musovic Saliha, Man Mohan Shrestha, Ali Komai, Charlotta S Olofsson
Biochemical and Biophysical Research Communications - 2021 -
A systems biology analysis of adrenergically stimulated adiponectin exocytosis in white
adipocytes
W. Lovfors, C. Simonsson, Ali Komai, E. Nyman, Charlotta S Olofsson, G. Cedersund
Journal of Biological Chemistry - 2021 -
An Approach to Monitor Exocytosis in White
Adipocytes
Ali Komai, Man Mohan Shrestha, Musovic Saliha, Charlotta S Olofsson
Exocytosis and Endocytosis. Florence Niedergang, Nicolas Vitale, Stéphane Gasman (red.) - 2021 -
CaV1.2 and CaV1.3 voltage-gated L-type Ca2+ channels in rat white fat
adipocytes
O. A. Fedorenko, P. Pulbutr, Elin Banke, N. E. Akaniro-Ejim, D. C. Bentley, Charlotta S Olofsson, S. Chan, P. A. Smith
Journal of Endocrinology - 2020 -
Adiponectin is secreted via caveolin 1-dependent mechanisms in white
adipocytes
Cecilia Brännmark, Emma I. Kay, U. O. Kugelberg, Belén Chanclón, Man Mohan Shrestha, Ingrid Wernstedt Asterholm, P. Stralfors, Charlotta S Olofsson
Journal of Endocrinology - 2020 -
Parabrachial Interleukin-6 Reduces Body Weight and Food Intake and Increases Thermogenesis to Regulate Energy
Metabolism
Devesh Mishra, Jennifer E. Richard, Ivana Maric, B. Porteiro, M. Haring, S. Kooijman, Musovic Saliha, Kim Eerola, Lorena Lopez-Ferreras, Eduard Peris, Katarzyna Grycel, Olesya Shevchouk, Peter Micallef, Charlotta S Olofsson, Ingrid Wernstedt Asterholm, H. J. Grill, R. Nogueiras, Karolina P Skibicka
Cell Reports - 2019 -
Antioxidant treatment induces reductive stress associated with mitochondrial dysfunction in
adipocytes
Eduard Peris, Peter Micallef, A. Paul, Vilborg Palsdottir, A. Enejder, Marco Bauzá-Thorbrügge, Charlotta S Olofsson, Ingrid Wernstedt Asterholm
Journal of Biological Chemistry - 2019 -
Adrenergic stimulation of adiponectin secretion in visceral mouse adipocytes is blunted in high-fat diet induced
obesity
Musovic Saliha, Charlotta S Olofsson
Scientific Reports - 2019 -
Extracellular ATP activates store-operated Ca2+ entry in white adipocytes: functional evidence for STIM1 and
ORAI1
Michael El Hachmane, Anna Ermund, Cecilia Brännmark, Charlotta S Olofsson
Biochemical Journal - 2018 -
Inhibition of FOXO1 transcription factor in primary human adipocytes mimics the insulin-resistant state of type 2
diabetes
M. R. Rajan, E. Nyman, Cecilia Brännmark, Charlotta S Olofsson, P. Stralfors
Biochemical Journal - 2018 -
A mechanically activated TRPC1-like current in white
adipocytes
Michael El Hachmane, Charlotta S Olofsson
Biochemical and Biophysical Research Communications - 2018 -
Mathematical modeling of white adipocyte exocytosis predicts adiponectin secretion and quantifies the rates of vesicle exo- and
endocytosis
Cecilia Brännmark, W. Lovfors, Ali Komai, T. Axelsson, Michael El Hachmane, Musovic Saliha, A. Paul, E. Nyman, Charlotta S Olofsson
Journal of Biological Chemistry - 2017 -
Escherichia coli outer membrane vesicles can contribute to sepsis induced cardiac
dysfunction.
Kristina Svennerholm, Kyong-Su Park, Johannes Wikström, Cecilia Lässer, Rossella Crescitelli, Ganesh V Shelke, Su Chul Jang, Shintaro Suzuki, Elga Bandeira, Charlotta S Olofsson, Jan Lötvall
Scientific reports - 2017 -
White Adipocyte Adiponectin Exocytosis Is Stimulated via beta(3)-Adrenergic Signaling and Activation of Epac1: Catecholamine Resistance in Obesity and Type 2
Diabetes
Ali Komai, Musovic Saliha, Eduard Peris, Ahmed Alrifaiy, Michael El Hachmane, Marcus Johansson, Ingrid Wernstedt Asterholm, Charlotta S Olofsson
Diabetes - 2016 -
Cooling Reduces cAMP-Stimulated Exocytosis and Adiponectin Secretion at a Ca2+-Dependent Step in 3T3-L1
Adipocytes
Michael El Hachmane, Ali Komai, Charlotta S Olofsson
Plos One - 2015 -
PKA-independent cAMP stimulation of white adipocyte exocytosis and adipokine secretion: Modulations by Ca2+ and
ATP
Ali Komai, C. Brännmark, Musovic Saliha, Charlotta S Olofsson
Journal of Physiology - 2014 -
Impact of hypoxia, simulated ischemia and reperfusion in HL-1 cells on the expression of FKBP12/FKBP12.6 and intracellular calcium
dynamics
Karin Åström-Olsson, Lizhen Li, Charlotta S Olofsson, Jan Borén, H. Ohlin, Lars Grip
Biochemical and Biophysical Research Communications - 2012 -
Suppression of sulfonylurea- and glucose-induced insulin secretion in vitro and in vivo in mice lacking the chloride transport protein
ClC-3.
Dai-Qing Li, Xingjun Jing, Albert Salehi, Stephan C Collins, Michael B Hoppa, Anders H. Rosengren, Enming Zhang, Ingmar Lundquist, Charlotta S Olofsson, Matthias Mörgelin, Lena Eliasson, Patrik Rorsman, Erik Renström
Cell metabolism - 2009 -
Impaired insulin exocytosis in neural cell adhesion molecule-/- mice due to defective reorganization of the submembrane F-actin
network.
Charlotta S Olofsson, Joakim Håkansson, Albert Salehi, Martin Bengtsson, Juris Galvanovskis, Chris Partridge, Maria SörhedeWinzell, Xiaojie Xian, Lena Eliasson, Ingmar Lundquist, Henrik Semb, Patrik Rorsman
Endocrinology - 2009 -
Long-term exposure of mouse pancreatic islets to oleate or palmitate results in reduced glucose-induced somatostatin and oversecretion of
glucagon
S. C. Collins, A. Salehi, L. Eliasson, Charlotta S Olofsson, P. Rorsman
Diabetologia - 2008