- Home
- About
- Find staff
- Ann-Mari Svennerholm
Ann-Mari Svennerholm
Senior Researcher
Department of Microbiology and Immunology-
Use of a TaqMan Array Card for identification of enterotoxins and colonization factors directly from stool samples in an enterotoxigenic <i>E. coli</i> vaccine
study
Jie Liu, T. Sakari Jokiranta, Nils Carlin, Suzanne Stroup, Jixian Zhang, Bjorn Sjostrand, Ann-Mari Svennerholm, Eric R. Houpt, Anu Kantele
MICROBIOLOGY SPECTRUM - 2025 -
The Incidence and Risk Factors for Enterotoxigenic E. coli Diarrheal Disease in Children under Three Years Old in Lusaka,
Zambia
Nsofwa Sukwa, Samuel Bosomprah, Paul Somwe, Monde Muyoyeta, Kapambwe Mwape, Kennedy Chibesa, Charlie Chaluma Luchen, Suwilanji Silwamba, Bavin Mulenga, Masiliso Munyinda, Seke Muzazu, Masuzyo Chirwa, Mwelwa Chibuye, Michelo Simuyandi, Roma Chilengi, Ann-Mari Svennerholm
MICROORGANISMS - 2024 -
Colonization factors of human and animal-specific enterotoxigenic Escherichia coli
(ETEC)
Astrid von Mentzer, Ann-Mari Svennerholm
Trends in Microbiology - 2024 -
A Perspective on the Strategy for Advancing ETVAX®, An Anti-ETEC Diarrheal Disease Vaccine, into a Field Efficacy Trial in Gambian Children: Rationale, Challenges, Lessons Learned, and Future
Directions
M. Jahangir Hossain, Ann-Mari Svennerholm, Nils Carlin, Umberto D'Alessandro, Thomas F. Wierzba
MICROORGANISMS - 2024 -
Developments in oral enterotoxigenic Escherichia coli
vaccines
Ann-Mari Svennerholm, Anna Lundgren
Current Opinion in Immunology - 2023 -
Efficacy of an Enterotoxigenic <i>Escherichia coli</i> (ETEC) Vaccine on the Incidence and Severity of Traveler's Diarrhea (TD): Evaluation of Alternative Endpoints and a TD Severity
Score
N. Maier, S. L. Grahek, J. Halpern, S. Restrepo, F. Troncoso, J. Shimko, O. Torres, J. Belkind-Gerson, D. A. Sack, Ann-Mari Svennerholm, B. Gustafsson, B. Sjostrand, N. Carlin, A. L. Bourgeois, C. K. Porter
Microorganisms - 2023 -
Safety and immunogenicity of ETVAX (R), an oral inactivated vaccine against enterotoxigenic Escherichia coli diarrhoea: a double-blinded, randomized, placebo-controlled trial amongst Finnish travellers to Benin, West
Africa
A. Kantele, M. Riekkinen, T. S. Jokiranta, S. H. Pakkanen, J. P. Pietila, A. Patjas, M. Eriksson, T. Khawaja, P. Klemets, K. Marttinen, H. Siikamaki, Anna Lundgren, Jan Holmgren, A. Lissmats, N. Carlin, Ann-Mari Svennerholm
Journal of Travel Medicine - 2023 -
Induction of mucosal and systemic immune responses against the common O78 antigen of an oral inactivated ETEC vaccine in Bangladeshi children and
infants
Ann-Mari Svennerholm, F. Qadri, Anna Lundgren, Joanna Kaim, T. R. Bhuiyan, M. Akhtar, N. Maier, A. L. Bourgeois, R. I. Walker
Vaccine - 2022 -
Enterotoxigenic Escherichia coli (ETEC) vaccines: Priority activities to enable product development, licensure, and global
access
Ibrahim Khalil, Richard Walker, Chad K. Porter, Farzana Muhib, Roma Chilengi, Alejandro Cravioto, Richard Guerrant, Ann-Mari Svennerholm, Firdausi Qadri, Shahida Baqar, Margaret Kosek, Gagandeep Kang, Claudio Lanata, George Armah, Thomas Wierzba, Mateusz Hasso-Agopsowicz, Birgitte Giersing, A. Louis Bourgeois
Vaccine - 2021 -
Mucosal Immune Responses Against an Oral Enterotoxigenic Escherichia coli Vaccine Evaluated in Clinical
Trials
Ann-Mari Svennerholm, Anna Lundgren, Susannah Leach, M. Akhtar, F. Qadri
Journal of Infectious Diseases - 2021 -
Long-read-sequenced reference genomes of the seven major lineages of enterotoxigenic Escherichia coli (ETEC) circulating in modern
time
Astrid von Mentzer, G. A. Blackwell, D. Pickard, C. J. Boinett, E. Joffre, A. J. Page, Ann-Mari Svennerholm, G. Dougan, A. Sjoling
Scientific Reports - 2021 -
A Systems Biology Approach Identifies B Cell Maturation Antigen (BCMA) as a Biomarker Reflecting Oral Vaccine Induced IgA Antibody Responses in
Humans
Lynda Mottram, Anna Lundgren, Ann-Mari Svennerholm, Susannah Leach
Frontiers in Immunology - 2021 -
The Intriguing Interaction of Escherichia coli with the Host Environment and Innovative Strategies To Interfere with Colonization: a Summary of the 2019 E. coli and the Mucosal Immune System
Meeting
E. Cox, M. Aloulou, J. M. Fleckenstein, C. Schaffer, A. Sjoling, S. Schuller, K. Hanevik, B. Devriendt, W. P. Zhang, Ann-Mari Svennerholm, E. G. Dudley
Applied and environmental microbiology - 2020 -
Safety and immunogenicity of the oral, inactivated, enterotoxigenic Escherichia coli vaccine ETVAX in Bangladeshi children and infants: a double-blind, randomised, placebo-controlled phase 1/2
trial
F. Qadri, M. Akhtar, T. R. Bhuiyan, M. I. Chowdhury, T. Ahmed, T. A. Rafique, A. Khan, S. I. A. Rahman, F. Khanam, Anna Lundgren, Gudrun Wiklund, Joanna Kaim, Madeleine Löfstrand, N. Carlin, A. L. Bourgeois, N. Maier, A. Fix, T. Wierzba, R. I. Walker, Ann-Mari Svennerholm
Lancet Infectious Diseases - 2020 -
Clinical aspects of heat-labile and heat-stable toxin-producing enterotoxigenic Escherichia coli: A prospective study among Finnish
travellers
K. Turunen, J. Antikainen, T. Laaveri, J. Kirveskari, Ann-Mari Svennerholm, A. Kantele
Travel Medicine and Infectious Disease - 2020 -
Oral vaccines for enterotoxigenic escherichia
coli
N. Carlin, Ann-Mari Svennerholm
Mucosal Vaccines (Second Edition). Innovation for Preventing Infectious Diseases. Hiroshi Kiyono and David W. Pascual (red.) - 2020 -
Booster vaccination with a fractional dose of an oral cholera vaccine induces comparable vaccine-specific antibody avidity as a full dose: A randomised clinical
trial.
Lynda Mottram, Anna Lundgren, Ann-Mari Svennerholm, Susannah Leach
Vaccine - 2020 -
Colonization factors among enterotoxigenic Escherichia coli isolates from children with moderate-to-severe diarrhea and from matched controls in the Global Enteric Multicenter Study
(GEMS)
R. M. Vidal, K. Muhsen, S. M. Tennant, Ann-Mari Svennerholm, S. O. Sow, D. Sur, A. K. M. Zaidi, A. S. G. Faruque, D. Saha, R. Adegbola, M. J. Hossain, P. L. Alonso, R. F. Breiman, Q. Bassat, B. Tamboura, D. Sanogo, U. Onwuchekwa, B. Manna, T. Ramamurthy, S. Kanungo, S. Ahmed, S. Qureshi, F. Quadri, A. Hossain, S. K. Das, M. Antonio, I. Mandomando, T. Nhampossa, S. Acacio, R. Omore, J. B. Ochieng, J. O. Oundo, E. D. Mintz, C. E. O'Reilly, L. Y. Berkeley, S. Livio, S. Panchalingam, D. Nasrin, T. H. Farag, Y. K. Wu, H. Sommerfelt, R. M. Robins-Browne, F. Del Canto, T. H. Hazen, D. A. Rasko, K. L. Kotloff, J. P. Nataro, M. M. Levine, Infection Ron J, V. P. Immunity, Infection Ron J, V. P. Immunity
Plos Neglected Tropical Diseases - 2019 -
Role of antigen specific T and B cells in systemic and mucosal immune responses in ETEC and Shigella infections, and their potential to serve as correlates of protection in vaccine
development
S. Mani, F. R. Toapanta, M. A. McArthur, F. Qadri, Ann-Mari Svennerholm, B. Devriendt, A. Phalipon, D. Cohen, M. B. Sztein
Vaccine - 2019 -
Evaluation of the safety and immunogenicity of the oral inactivated multivalent enterotoxigenic Escherichia coli vaccine ETVAX in Bangladeshi adults in a double-blind, randomized, placebo-controlled Phase I trial using electrochemiluminescence and ELISA assays for immunogenicity
analyses
M. Akhtar, M. I. Chowdhury, T. R. Bhuiyan, Joanna Kaim, T. Ahmed, T. A. Rafique, A. Khan, S. I. A. Rahman, F. Khanam, Y. A. Begum, M. Z. Sharif, L. N. Islam, N. Carlin, N. Maier, A. Fix, T. F. Wierzba, R. I. Walker, A. L. Bourgeois, Ann-Mari Svennerholm, F. Qadri, Anna Lundgren
Vaccine - 2019 -
Assessing antigen specific HLA-DR plus antibody secreting cell (DR plus ASC) responses in whole blood in enteric infections using an ELISPOT
technique
T. R. Bhuiyan, M. R. Hoq, N. S. Nishat, D. Al Mahbuba, R. Rashu, K. Islam, L. Hossain, J. B. Harris, E. T. Ryan, S. B. Calderwood, Ann-Mari Svennerholm, F. Qadri
Microbes and Infection - 2018 -
Glyco-engineered cell line and computational docking studies reveals enterotoxigenic Escherichia coli CFA/I fimbriae bind to Lewis a
glycans
Lynda Mottram, Jining Liu, Sonali Chavan, Joshua Tobias, Ann-Mari Svennerholm, Jan Holgersson
Scientific Reports - 2018 -
FUT2 non-secretor status is associated with altered susceptibility to symptomatic enterotoxigenic Escherichia coli infection in
Bangladeshiw
Lynda Mottram, Gudrun Wiklund, Göran Larson, F. Qadri, Ann-Mari Svennerholm
Scientific Reports - 2017 -
Kinetics of antibody-secreting cell and fecal IgA responses after oral cholera vaccination in different age groups in a cholera endemic
country
M. Akhtar, F. Qadri, T. R. Bhuiyan, S. Akter, T. A. Rafique, A. Khan, L. N. Islam, A. Saha, Ann-Mari Svennerholm, Anna Lundgren
Vaccine - 2017 -
Cross-reactivity and avidity of antibody responses induced in humans by the oral inactivated multivalent enterotoxigenic Escherichia coli (ETEC) vaccine
ETVAX
Susannah Leach, Anna Lundgren, N. Carlin, Madeleine Löfstrand, Ann-Mari Svennerholm
Vaccine - 2017 -
Gastric expression of IL-17A and IFNγ in Helicobacter pylori infected individuals is related to
symptoms
Jenni Adamsson, Louise Sjökvist Ottsjö, Samuel B Lundin, Ann-Mari Svennerholm, Sukanya Raghavan
Cytokine - 2017 -
Identification and characterization of the novel colonization factor CS30 based on whole genome sequencing in enterotoxigenic Escherichia coli
(ETEC)
Astrid von Mentzer, Joshua Tobias, Gudrun Wiklund, Stefan Nordqvist, M. Aslett, G. Dougan, A. Sjoling, Ann-Mari Svennerholm
Scientific Reports - 2017 -
Surface expression of Helicobacter pylori HpaA adhesion antigen on Vibrio cholerae, enhanced by co-expressed enterotoxigenic Escherichia coli fimbrial
antigens
Joshua Tobias, Michael Lebens, S. N. Wai, Jan Holmgren, Ann-Mari Svennerholm
Microbial Pathogenesis - 2017 -
Antibakteriella ämnens roll i
resistensutveckling
D. G. Joakim Larsson, Ann-Mari Svennerholm
Läkartidningen - 2016 -
Enumeration of Gut-Homing beta 7-Positive, Pathogen-Specific Antibody-Secreting Cells in Whole Blood from Enterotoxigenic Escherichia coli- and Vibrio cholerae-Infected Patients, Determined Using an Enzyme-Linked Immunosorbent Spot Assay
Technique
T. R. Bhuiyan, M. R. Hoq, N. S. Nishat, D. Al Mahbuba, R. Rashu, K. Islam, L. Hossain, A. Dey, J. B. Harris, E. T. Ryan, S. B. Calderwood, Ann-Mari Svennerholm, F. Qadri
Clinical and Vaccine Immunology - 2016 -
Resistance Pattern and Molecular Characterization of Enterotoxigenic Escherichia coli (ETEC) Strains Isolated in
Bangladesh
Y. A. Begum, K. A. Talukder, I. J. Azmi, M. Shahnaij, A. Sheikh, S. Sharmin, Ann-Mari Svennerholm, F. Qadri
Plos One - 2016 -
Identification of new heat-stable (STa) enterotoxin allele variants produced by human enterotoxigenic Escherichia coli
(ETEC)
Enrique Joffre, Astrid von Mentzer, Ann-Mari Svennerholm, A. Sjoling
International Journal of Medical Microbiology - 2016 -
Stability of the Encoding Plasmids and Surface Expression of CS6 Differs in Enterotoxigenic Escherichia coli (ETEC) Encoding Different Heat-Stable (ST) Enterotoxins (STh and
STp)
Joshua Tobias, Astrid von Mentzer, Patricia Loayza Frykberg, M. Aslett, A. J. Page, Åsa Sjöling, Ann-Mari Svennerholm
Plos One - 2016 -
Induction of long term mucosal immunological memory in humans by an oral inactivated multivalent enterotoxigenic Escherichia coli
vaccine
Anna Lundgren, Marianne Jertborn, Ann-Mari Svennerholm
Vaccine - 2016 -
Helicobacter pylori Infection of the Gastric
Mucosa
Sukanya Raghavan, Jan Holmgren, Ann-Mari Svennerholm
Mucosal Immunology: Fourth Edition - 2015 -
Toxins and virulence factors of enterotoxigenic Escherichia coli associated with strains isolated from indigenous children and international visitors to a rural community in
Guatemala
O. R. Torres, W. Gonzalez, O. Lemus, R. A. Pratdesaba, J. A. Matute, Gudrun Wiklund, D. A. Sack, A. L. Bourgeois, Ann-Mari Svennerholm
Epidemiology and Infection - 2015 -
Allele Variants of Enterotoxigenic Escherichia coli Heat-Labile Toxin Are Globally Transmitted and Associated with Colonization
Factors
Enrique Joffre, Astrid von Mentzer, M. Abd El Ghany, N. Oezguen, T. Savidge, G. Dougan, Ann-Mari Svennerholm, Åsa Sjöling
Journal of Bacteriology - 2015 -
Implications of enterotoxigenic Escherichia coli genomics for vaccine
development
Åsa Sjöling, Astrid von Mentzer, Ann-Mari Svennerholm
Expert Review of Vaccines - 2015 -
A comparison of seasonal variations in rotavirus antibodies in the breast milk of Swedish and Bangladeshi
mothers
Daniel Novak, Ann-Mari Svennerholm
Acta Paediatrica - 2015 -
Safety and immunogenicity of an improved oral inactivated multivalent enterotoxigenic Escherichia coli (ETEC) vaccine administered alone and together with dmLT adjuvant in a double-blind, randomized, placebo-controlled Phase I
study
Anna Lundgren, L. Bourgeois, N. Carlin, J. Clements, B. Gustafsson, Marianne Hartford, J. Holmgren, Max Petzold, R. Walker, Ann-Mari Svennerholm
Vaccine - 2014 -
Identification of enterotoxigenic Escherichia coli (ETEC) clades with long-term global
distribution
Astrid von Mentzer, T. R. Connor, L. H. Wieler, T. Semmler, A. Iguchi, N. R. Thomson, D. A. Rasko, Enrique Joffre, J. Corander, D. Pickard, Gudrun Wiklund, Ann-Mari Svennerholm, Åsa Sjöling, G. Dougan
Nature Genetics - 2014 -
Shift in Phenotypic Characteristics of Enterotoxigenic Escherichia coli (ETEC) Isolated from Diarrheal Patients in
Bangladesh
Y. A. Begum, N. I. Baby, A. S. G. Faruque, N. Jahan, A. Cravioto, Ann-Mari Svennerholm, F. Qadri
Plos Neglected Tropical Diseases - 2014 -
Diarrhea Burden Due to Natural Infection with Enterotoxigenic Escherichia coli in a Birth Cohort in a Rural Egyptian
Community
A. Mansour, H. I. Shaheen, M. Amine, K. Hassan, J. W. Sanders, M. S. Riddle, A. W. Armstrong, Ann-Mari Svennerholm, P. J. Sebeny, J. D. Klena, S. Y. N. Young, R. W. Frenck, England V. P. Mbridge
Journal of Clinical Microbiology - 2014 -
Antigen-Specific Memory B-cell Responses to Enterotoxigenic Escherichia coli Infection in Bangladeshi
Adults
M. Alam, A. Amena, S. Afrin, M. Rahman, S. Aktar, T. Uddin, M. A. Rahman, D. Al Mahbuba, F. Chowdhury, A. Khan, T. Bhuiyan, Y. Begum, E. Ryan, S. Calderwood, Ann-Mari Svennerholm, F. Qadri
PLoS Neglected Tropical Diseases - 2014 -
Evaluation of immune responses to an oral typhoid vaccine, Ty21a, in children from 2 to 5 years of age in
Bangladesh
Taufiqur Rahman Bhuiyan, F. K. Choudhury, F. Khanam, A. Saha, Md A. Sayeed, U. Salma, Anna Lundgren, D. A. Sack, Ann-Mari Svennerholm, F. Qadri
Vaccine - 2014 -
Pathogenicity and Phenotypic Characterization of Enterotoxigenic Escherichia coli Isolates from a Birth Cohort of Children in Rural
Egypt
A. Mansour, H. I. Shaheen, M. Amine, K. Hassan, J. W. Sanders, M. S. Riddle, A. W. Armstrong, Ann-Mari Svennerholm, P. J. Sebeny, J. D. Klena, S. Y. N. Young, R. W. Frenck
Journal of Clinical Microbiology - 2014 -
Immune Responses Against Helicobacter pylori in Gastric Cancer Patients and in Risk Groups for Gastric
Cancer.
Jenni Adamsson, Samuel B Lundin, Lars-Erik Hansson, Henrik Sjövall, Ann-Mari Svennerholm
Helicobacter - 2013 -
Prevalence, seasonality and severity of disease of pathogenic Escherichia coli in children with diarrhea in
Bolivia.
Lucia Gonzales, Enrique Joffre, Rosario Rivera, Åsa Sjöling, Ann-Mari Svennerholm, Volga Iniguez
Journal of Medical Microbiology - 2013 -
Different kinetics of circulating antibody-secreting cell responses after primary and booster oral immunizations: A tool for assessing immunological
memory.
Susannah Leach, Anna Lundgren, Ann-Mari Svennerholm
Vaccine - 2013 -
Development and preclinical evaluation of safety and immunogenicity of an oral ETEC vaccine containing inactivated E. coli bacteria overexpressing colonization factors CFA/I, CS3, CS5 and CS6 combined with a hybrid LT/CT B subunit antigen, administered alone and together with dmLT
adjuvant.
Jan Holmgren, L Bourgeois, N Carlin, J Clements, B Gustafsson, Anna Lundgren, Erik Nygren, Joshua Tobias, R Walker, Ann-Mari Svennerholm
Vaccine - 2013
More publications
We have limited the number of publications on this page. Visit GUP (The Publication Database for Gothenburg University) to find more publications.