Ann-Mari Svennerholm
Seniorforskare
Department of Microbiology and-
Induction of mucosal and systemic immune responses against the common O78 antigen of an oral inactivated ETEC vaccine in Bangladeshi children and
infants
Ann-Mari Svennerholm, F. Qadri, Anna Lundgren, Joanna Kaim, T. R. Bhuiyan, M. Akhtar, N. Maier, A. L. Bourgeois, R. I. Walker
Vaccine - 2022 -
Mucosal Immune Responses Against an Oral Enterotoxigenic Escherichia coli Vaccine Evaluated in Clinical
Trials
Ann-Mari Svennerholm, Anna Lundgren, Susannah Leach, M. Akhtar, F. Qadri
Journal of Infectious Diseases - 2021 -
Enterotoxigenic Escherichia coli (ETEC) vaccines: Priority activities to enable product development, licensure, and global
access
Ibrahim Khalil, Richard Walker, Chad K. Porter, Farzana Muhib, Roma Chilengi, Alejandro Cravioto, Richard Guerrant, Ann-Mari Svennerholm, Firdausi Qadri, Shahida Baqar, Margaret Kosek, Gagandeep Kang, Claudio Lanata, George Armah, Thomas Wierzba, Mateusz Hasso-Agopsowicz, Birgitte Giersing, A. Louis Bourgeois
Vaccine - 2021 -
A Systems Biology Approach Identifies B Cell Maturation Antigen (BCMA) as a Biomarker Reflecting Oral Vaccine Induced IgA Antibody Responses in
Humans
Lynda Mottram, Anna Lundgren, Ann-Mari Svennerholm, Susannah Leach
Frontiers in Immunology - 2021 -
Long-read-sequenced reference genomes of the seven major lineages of enterotoxigenic Escherichia coli (ETEC) circulating in modern
time
Astrid von Mentzer, G. A. Blackwell, D. Pickard, C. J. Boinett, E. Joffre, A. J. Page, Ann-Mari Svennerholm, G. Dougan, A. Sjoling
Scientific Reports - 2021 -
Clinical aspects of heat-labile and heat-stable toxin-producing enterotoxigenic Escherichia coli: A prospective study among Finnish
travellers
K. Turunen, J. Antikainen, T. Laaveri, J. Kirveskari, Ann-Mari Svennerholm, A. Kantele
Travel Medicine and Infectious Disease - 2020 -
The Intriguing Interaction of Escherichia coli with the Host Environment and Innovative Strategies To Interfere with Colonization: a Summary of the 2019 E. coli and the Mucosal Immune System
Meeting
E. Cox, M. Aloulou, J. M. Fleckenstein, C. Schaffer, A. Sjoling, S. Schuller, K. Hanevik, B. Devriendt, W. P. Zhang, Ann-Mari Svennerholm, E. G. Dudley
Applied and environmental microbiology - 2020 -
Oral vaccines for enterotoxigenic escherichia
coli
N. Carlin, Ann-Mari Svennerholm
Mucosal Vaccines (Second Edition). Innovation for Preventing Infectious Diseases. Hiroshi Kiyono and David W. Pascual (red.) - 2020 -
Safety and immunogenicity of the oral, inactivated, enterotoxigenic Escherichia coli vaccine ETVAX in Bangladeshi children and infants: a double-blind, randomised, placebo-controlled phase 1/2
trial
F. Qadri, M. Akhtar, T. R. Bhuiyan, M. I. Chowdhury, T. Ahmed, T. A. Rafique, A. Khan, S. I. A. Rahman, F. Khanam, Anna Lundgren, Gudrun Wiklund, Joanna Kaim, Madeleine Löfstrand, N. Carlin, A. L. Bourgeois, N. Maier, A. Fix, T. Wierzba, R. I. Walker, Ann-Mari Svennerholm
Lancet Infectious Diseases - 2020 -
Booster vaccination with a fractional dose of an oral cholera vaccine induces comparable vaccine-specific antibody avidity as a full dose: A randomised clinical
trial.
Lynda Mottram, Anna Lundgren, Ann-Mari Svennerholm, Susannah Leach
Vaccine - 2020 -
Role of antigen specific T and B cells in systemic and mucosal immune responses in ETEC and Shigella infections, and their potential to serve as correlates of protection in vaccine
development
S. Mani, F. R. Toapanta, M. A. McArthur, F. Qadri, Ann-Mari Svennerholm, B. Devriendt, A. Phalipon, D. Cohen, M. B. Sztein
Vaccine - 2019 -
Evaluation of the safety and immunogenicity of the oral inactivated multivalent enterotoxigenic Escherichia coli vaccine ETVAX in Bangladeshi adults in a double-blind, randomized, placebo-controlled Phase I trial using electrochemiluminescence and ELISA assays for immunogenicity
analyses
M. Akhtar, M. I. Chowdhury, T. R. Bhuiyan, Joanna Kaim, T. Ahmed, T. A. Rafique, A. Khan, S. I. A. Rahman, F. Khanam, Y. A. Begum, M. Z. Sharif, L. N. Islam, N. Carlin, N. Maier, A. Fix, T. F. Wierzba, R. I. Walker, A. L. Bourgeois, Ann-Mari Svennerholm, F. Qadri, Anna Lundgren
Vaccine - 2019 -
Colonization factors among enterotoxigenic Escherichia coli isolates from children with moderate-to-severe diarrhea and from matched controls in the Global Enteric Multicenter Study
(GEMS)
R. M. Vidal, K. Muhsen, S. M. Tennant, Ann-Mari Svennerholm, S. O. Sow, D. Sur, A. K. M. Zaidi, A. S. G. Faruque, D. Saha, R. Adegbola, M. J. Hossain, P. L. Alonso, R. F. Breiman, Q. Bassat, B. Tamboura, D. Sanogo, U. Onwuchekwa, B. Manna, T. Ramamurthy, S. Kanungo, S. Ahmed, S. Qureshi, F. Quadri, A. Hossain, S. K. Das, M. Antonio, I. Mandomando, T. Nhampossa, S. Acacio, R. Omore, J. B. Ochieng, J. O. Oundo, E. D. Mintz, C. E. O'Reilly, L. Y. Berkeley, S. Livio, S. Panchalingam, D. Nasrin, T. H. Farag, Y. K. Wu, H. Sommerfelt, R. M. Robins-Browne, F. Del Canto, T. H. Hazen, D. A. Rasko, K. L. Kotloff, J. P. Nataro, M. M. Levine, Infection Ron J, V. P. Immunity, Infection Ron J, V. P. Immunity
Plos Neglected Tropical Diseases - 2019 -
Glyco-engineered cell line and computational docking studies reveals enterotoxigenic Escherichia coli CFA/I fimbriae bind to Lewis a
glycans
Lynda Mottram, Jining Liu, Sonali Chavan, Joshua Tobias, Ann-Mari Svennerholm, Jan Holgersson
Scientific Reports - 2018 -
Assessing antigen specific HLA-DR plus antibody secreting cell (DR plus ASC) responses in whole blood in enteric infections using an ELISPOT
technique
T. R. Bhuiyan, M. R. Hoq, N. S. Nishat, D. Al Mahbuba, R. Rashu, K. Islam, L. Hossain, J. B. Harris, E. T. Ryan, S. B. Calderwood, Ann-Mari Svennerholm, F. Qadri
Microbes and Infection - 2018 -
Cross-reactivity and avidity of antibody responses induced in humans by the oral inactivated multivalent enterotoxigenic Escherichia coli (ETEC) vaccine
ETVAX
Susannah Leach, Anna Lundgren, N. Carlin, Madeleine Löfstrand, Ann-Mari Svennerholm
Vaccine - 2017 -
Gastric expression of IL-17A and IFNγ in Helicobacter pylori infected individuals is related to
symptoms
Jenni Adamsson, Louise Sjökvist Ottsjö, Samuel B Lundin, Ann-Mari Svennerholm, Sukanya Raghavan
Cytokine - 2017 -
FUT2 non-secretor status is associated with altered susceptibility to symptomatic enterotoxigenic Escherichia coli infection in
Bangladeshiw
Lynda Mottram, Gudrun Wiklund, Göran Larson, F. Qadri, Ann-Mari Svennerholm
Scientific Reports - 2017 -
Identification and characterization of the novel colonization factor CS30 based on whole genome sequencing in enterotoxigenic Escherichia coli
(ETEC)
Astrid von Mentzer, Joshua Tobias, Gudrun Wiklund, Stefan Nordqvist, M. Aslett, G. Dougan, A. Sjoling, Ann-Mari Svennerholm
Scientific Reports - 2017 -
Surface expression of Helicobacter pylori HpaA adhesion antigen on Vibrio cholerae, enhanced by co-expressed enterotoxigenic Escherichia coli fimbrial
antigens
Joshua Tobias, Michael Lebens, S. N. Wai, Jan Holmgren, Ann-Mari Svennerholm
Microbial Pathogenesis - 2017 -
Kinetics of antibody-secreting cell and fecal IgA responses after oral cholera vaccination in different age groups in a cholera endemic
country
M. Akhtar, F. Qadri, T. R. Bhuiyan, S. Akter, T. A. Rafique, A. Khan, L. N. Islam, A. Saha, Ann-Mari Svennerholm, Anna Lundgren
Vaccine - 2017 -
Antibakteriella ämnens roll i
resistensutveckling
D. G. Joakim Larsson, Ann-Mari Svennerholm
Läkartidningen - 2016 -
Identification of new heat-stable (STa) enterotoxin allele variants produced by human enterotoxigenic Escherichia coli
(ETEC)
Enrique Joffre, Astrid von Mentzer, Ann-Mari Svennerholm, A. Sjoling
International Journal of Medical Microbiology - 2016 -
Resistance Pattern and Molecular Characterization of Enterotoxigenic Escherichia coli (ETEC) Strains Isolated in
Bangladesh
Y. A. Begum, K. A. Talukder, I. J. Azmi, M. Shahnaij, A. Sheikh, S. Sharmin, Ann-Mari Svennerholm, F. Qadri
Plos One - 2016 -
Induction of long term mucosal immunological memory in humans by an oral inactivated multivalent enterotoxigenic Escherichia coli
vaccine
Anna Lundgren, Marianne Jertborn, Ann-Mari Svennerholm
Vaccine - 2016 -
Enumeration of Gut-Homing beta 7-Positive, Pathogen-Specific Antibody-Secreting Cells in Whole Blood from Enterotoxigenic Escherichia coli- and Vibrio cholerae-Infected Patients, Determined Using an Enzyme-Linked Immunosorbent Spot Assay
Technique
T. R. Bhuiyan, M. R. Hoq, N. S. Nishat, D. Al Mahbuba, R. Rashu, K. Islam, L. Hossain, A. Dey, J. B. Harris, E. T. Ryan, S. B. Calderwood, Ann-Mari Svennerholm, F. Qadri
Clinical and Vaccine Immunology - 2016 -
Stability of the Encoding Plasmids and Surface Expression of CS6 Differs in Enterotoxigenic Escherichia coli (ETEC) Encoding Different Heat-Stable (ST) Enterotoxins (STh and
STp)
Joshua Tobias, Astrid von Mentzer, Patricia Loayza Frykberg, M. Aslett, A. J. Page, Åsa Sjöling, Ann-Mari Svennerholm
Plos One - 2016 -
Helicobacter pylori Infection of the Gastric
Mucosa
Sukanya Raghavan, Jan Holmgren, Ann-Mari Svennerholm
Mucosal Immunology: Fourth Edition - 2015 -
Toxins and virulence factors of enterotoxigenic Escherichia coli associated with strains isolated from indigenous children and international visitors to a rural community in
Guatemala
O. R. Torres, W. Gonzalez, O. Lemus, R. A. Pratdesaba, J. A. Matute, Gudrun Wiklund, D. A. Sack, A. L. Bourgeois, Ann-Mari Svennerholm
Epidemiology and Infection - 2015 -
Allele Variants of Enterotoxigenic Escherichia coli Heat-Labile Toxin Are Globally Transmitted and Associated with Colonization
Factors
Enrique Joffre, Astrid von Mentzer, M. Abd El Ghany, N. Oezguen, T. Savidge, G. Dougan, Ann-Mari Svennerholm, Åsa Sjöling
Journal of Bacteriology - 2015 -
Implications of enterotoxigenic Escherichia coli genomics for vaccine
development
Åsa Sjöling, Astrid von Mentzer, Ann-Mari Svennerholm
Expert Review of Vaccines - 2015 -
A comparison of seasonal variations in rotavirus antibodies in the breast milk of Swedish and Bangladeshi
mothers
Daniel Novak, Ann-Mari Svennerholm
Acta Paediatrica - 2015 -
Safety and immunogenicity of an improved oral inactivated multivalent enterotoxigenic Escherichia coli (ETEC) vaccine administered alone and together with dmLT adjuvant in a double-blind, randomized, placebo-controlled Phase I
study
Anna Lundgren, L. Bourgeois, N. Carlin, J. Clements, B. Gustafsson, Marianne Hartford, J. Holmgren, Max Petzold, R. Walker, Ann-Mari Svennerholm
Vaccine - 2014 -
Identification of enterotoxigenic Escherichia coli (ETEC) clades with long-term global
distribution
Astrid von Mentzer, T. R. Connor, L. H. Wieler, T. Semmler, A. Iguchi, N. R. Thomson, D. A. Rasko, Enrique Joffre, J. Corander, D. Pickard, Gudrun Wiklund, Ann-Mari Svennerholm, Åsa Sjöling, G. Dougan
Nature Genetics - 2014 -
Shift in Phenotypic Characteristics of Enterotoxigenic Escherichia coli (ETEC) Isolated from Diarrheal Patients in
Bangladesh
Y. A. Begum, N. I. Baby, A. S. G. Faruque, N. Jahan, A. Cravioto, Ann-Mari Svennerholm, F. Qadri
Plos Neglected Tropical Diseases - 2014 -
Diarrhea Burden Due to Natural Infection with Enterotoxigenic Escherichia coli in a Birth Cohort in a Rural Egyptian
Community
A. Mansour, H. I. Shaheen, M. Amine, K. Hassan, J. W. Sanders, M. S. Riddle, A. W. Armstrong, Ann-Mari Svennerholm, P. J. Sebeny, J. D. Klena, S. Y. N. Young, R. W. Frenck, England V. P. Mbridge
Journal of Clinical Microbiology - 2014 -
Antigen-Specific Memory B-cell Responses to Enterotoxigenic Escherichia coli Infection in Bangladeshi
Adults
M. Alam, A. Amena, S. Afrin, M. Rahman, S. Aktar, T. Uddin, M. A. Rahman, D. Al Mahbuba, F. Chowdhury, A. Khan, T. Bhuiyan, Y. Begum, E. Ryan, S. Calderwood, Ann-Mari Svennerholm, F. Qadri
PLoS Neglected Tropical Diseases - 2014 -
Evaluation of immune responses to an oral typhoid vaccine, Ty21a, in children from 2 to 5 years of age in
Bangladesh
Taufiqur Rahman Bhuiyan, F. K. Choudhury, F. Khanam, A. Saha, Md A. Sayeed, U. Salma, Anna Lundgren, D. A. Sack, Ann-Mari Svennerholm, F. Qadri
Vaccine - 2014 -
Pathogenicity and Phenotypic Characterization of Enterotoxigenic Escherichia coli Isolates from a Birth Cohort of Children in Rural
Egypt
A. Mansour, H. I. Shaheen, M. Amine, K. Hassan, J. W. Sanders, M. S. Riddle, A. W. Armstrong, Ann-Mari Svennerholm, P. J. Sebeny, J. D. Klena, S. Y. N. Young, R. W. Frenck
Journal of Clinical Microbiology - 2014 -
Immune Responses Against Helicobacter pylori in Gastric Cancer Patients and in Risk Groups for Gastric
Cancer.
Jenni Adamsson, Samuel B Lundin, Lars-Erik Hansson, Henrik Sjövall, Ann-Mari Svennerholm
Helicobacter - 2013 -
Prevalence, seasonality and severity of disease of pathogenic Escherichia coli in children with diarrhea in
Bolivia.
Lucia Gonzales, Enrique Joffre, Rosario Rivera, Åsa Sjöling, Ann-Mari Svennerholm, Volga Iniguez
Journal of Medical Microbiology - 2013 -
Different kinetics of circulating antibody-secreting cell responses after primary and booster oral immunizations: A tool for assessing immunological
memory.
Susannah Leach, Anna Lundgren, Ann-Mari Svennerholm
Vaccine - 2013 -
Development and preclinical evaluation of safety and immunogenicity of an oral ETEC vaccine containing inactivated E. coli bacteria overexpressing colonization factors CFA/I, CS3, CS5 and CS6 combined with a hybrid LT/CT B subunit antigen, administered alone and together with dmLT
adjuvant.
Jan Holmgren, L Bourgeois, N Carlin, J Clements, B Gustafsson, Anna Lundgren, Erik Nygren, Joshua Tobias, R Walker, Ann-Mari Svennerholm
Vaccine - 2013 -
Molecular Characterization of Enterotoxigenic Escherichia coli Isolates Recovered from Children with Diarrhea during a 4-Year Period (2007 to 2010) in
Bolivia
Lucia Gonzales, S. Sanchez, S. Zambrana, V. Iniguez, Gudrun Wiklund, Ann-Mari Svennerholm, Åsa Sjöling
Journal of Clinical Microbiology - 2013 -
Clinical trial to evaluate safety and immunogenicity of an oral inactivated enterotoxigenic Escherichia coli prototype vaccine containing CFA/I overexpressing bacteria and recombinantly produced LTB/CTB hybrid
protein.
Anna Lundgren, Susannah Leach, Joshua Tobias, N Carlin, B Gustafsson, Marianne Jertborn, L Bourgeois, R Walker, Jan Holmgren, Ann-Mari Svennerholm
Vaccine - 2013 -
Immune responses and protection in children in developing countries induced by oral
vaccines.
Firdausi Qadria, Taufiqur Rahman Bhuiyan, David A. Sack, Ann-Mari Svennerholm
Vaccine - 2013 -
Vaccine specific immune response to an inactivated oral cholera vaccine and EPI vaccines in a high and low arsenic area in Bangladeshi
children
Amit Saha, Mohiul Chowdhury, Mohammad Nazim, Mohammad Murshid Alam, Tanvir Ahmed, Mohammad Bakhtiar Hossain, Samar Kumar Hore, Gazi Nurun Nahar Sultana, Ann-Mari Svennerholm, Firdausi Qadri
Vaccine - 2013 -
Diagnostic Microbiologic Methods in the GEMS-1 Case/Control
Study.
Sandra Panchalingam, Martin Antonio, Anowar Hossain, Inacio Mandomando, Ben Ochieng, Joseph Oundo, T. Ramamurthy, Boubou Tamboura, Anita K. M. Zaidi, William Petri, Eric Houpt, Patrick Murray, Valeria Prado, Roberto Vidal, Duncan Steele, Nancy Strockbine, Philippe Sansonetti, Roger I. Glass, Roy M. Robins-Browne, Marija Tauschek, Ann-Mari Svennerholm, Karen Kotloff, Myron M. Levine, James P. Nataro
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America - 2012 -
Vaccines against mucosal
infections.
Ann-Mari Svennerholm, Jan Holmgren
Current Opinion in Immunology - 2012 -
Strategies to overexpress enterotoxigenic Escherichia coli (ETEC) colonization factors for the construction of oral whole-cell inactivated ETEC vaccine
candidates.
Joshua Tobias, Ann-Mari Svennerholm
Applied microbiology and biotechnology - 2012 -
Recent progress toward an enterotoxigenic Escherichia coli
vaccine.
Ann-Mari Svennerholm, Anna Lundgren
Expert review of vaccines - 2012 -
Expression of colonization factor CS5 of enterotoxigenic Escherichia coli (ETEC) is enhanced in vivo and by the bile component Na glycocholate
hydrate.
Matilda Nicklasson, Åsa Sjöling, Astrid von Mentzer, Firdausi Qadri, Ann-Mari Svennerholm
PloS one - 2012 -
Enterotoxins, colonization factors, serotypes and antimicrobial resistance of enterotoxigenic Escherichia coli (ETEC) strains isolated from hospitalized children with diarrhoea in
Bolivia
Claudia Rodas, Rosalia Mamani, Jorge Blanco, Jesús Eulogio Blanco, Gudrun Wiklund, Ann-Mari Svennerholm, Åsa Sjöling, Volga Iniguez
Brazilian Journal of Infectious Diseases - 2011 -
Enterotoxins, colonization factors, serotypes and antimicrobial resistance of enterotoxigenic Escherichia coli (ETEC) strains isolated from hospitalized children with diarrhea in
Bolivia
Claudia Rodas, R Mamani, Jorge Blanco, Jesus Eulogio Blanco, Gudrun Wiklund, Ann-Mari Svennerholm, Åsa Sjöling, V Iniguez
BRAZILIAN JOURNAL OF INFECTIOUS DISEASES - 2011 -
From cholera to enterotoxigenic Escherichia coli (ETEC) vaccine
development
Ann-Mari Svennerholm
INDIAN JOURNAL OF MEDICAL RESEARCH - 2011 -
Refinement of a human challenge model for evaluation of enterotoxigenic Escherichia coli
vaccines.
Clayton Harro, Subhra Chakraborty, Andrea Feller, Barbara DeNearing, Alicia Cage, Malathi Ram, Anna Lundgren, Ann-Mari Svennerholm, August L Bourgeois, Richard I Walker, David A Sack
Clinical and vaccine immunology : CVI - 2011 -
Construction of a non-toxigenic Escherichia coli oral vaccine strain expressing large amounts of CS6 and inducing strong intestinal and serum anti-CS6 antibody responses in
mice.
Joshua Tobias, Ann-Mari Svennerholm, Nils I A Carlin, Michael Lebens, Jan Holmgren
Vaccine - 2011 -
Impact of rapid urbanization on the rates of infection by Vibrio cholerae O1 and enterotoxigenic Escherichia coli in Dhaka,
Bangladesh.
Fahima Chowdhury, Mohammad Arif Rahman, Yasmin A Begum, Ashraful I Khan, Abu S G Faruque, Nirod Chandra Saha, Nabilah Ibnat Baby, M A Malek, Anisha Rajeev Kumar, Ann-Mari Svennerholm, Mark Pietroni, Alejandro Cravioto, Firdausi Qadri
PLoS neglected tropical diseases - 2011 -
Impaired IFN-gamma Production after Stimulation with Bacterial Components by Natural Killer Cells from Gastric Cancer
Patients
Åsa Lindgren, Cheol H Yun, Åsa Sjöling, Camilla Berggren, Jia-Bin Sun, E Jonsson, Jan Holmgren, Ann-Mari Svennerholm, Samuel B Lundin
Experimental Cell Research - 2011 -
Immune responses to Helicobacter pylori infection in Bangladeshi children during their first two years of life and the association between maternal antibodies and onset of
infection.
Taufiqur Rahman Bhuiyan, Amit Saha, Anna Lundgren, Firdausi Qadri, Ann-Mari Svennerholm
The Journal of infectious diseases - 2010 -
CD8- natural killer cells are greatly enriched in the human gastrointestinal tract and have the capacity to respond to
bacteria.
Åsa Lindgren, Cheol H Yun, Anna Lundgren, Åsa Sjöling, Lena Öhman, Ann-Mari Svennerholm, Jan Holmgren, Samuel B Lundin
Journal of innate immunity - 2010 -
Detection of the CS20 colonization factor antigen in diffuse-adhering Escherichia coli
strains.
Theresa J Ochoa, Fulton P Rivera, Maria Bernal, Rina Meza, Lucie Ecker, Ana I Gil, David Cepeda, Susan Mosquito, Erik Mercado, Ryan C Maves, Eric R Hall, Ann-Mari Svennerholm, Annette McVeigh, Stephen Savarino, Claudio F Lanata
FEMS immunology and medical microbiology - 2010 -
Enterotoxigenic Escherichia coli multilocus sequence types in Guatemala and
Mexico
Matilda Nicklasson, John Klena, Claudia Rodas, Olga Torres, A Louis Bourgeois, Ann-Mari Svennerholm, Åsa Sjöling
Emerging Infectious Diseases - 2010 -
Isolation of a bacteriophage specific for CS7-expressing strains of enterotoxigenic Escherichia
coli
Y. A. Begum, S. Chakraborty, A. Chowdhury, A. N. Ghosh, G. B. Nair, R. B. Sack, Ann-Mari Svennerholm, F. Qadri
JOURNAL OF MEDICAL MICROBIOLOGY - 2010 -
Over-expression of major colonization factors of enterotoxigenic Escherichia coli, alone or together, on non-toxigenic E. coli
bacteria.
Joshua Tobias, Jan Holmgren, Maria Hellman, Erik Nygren, Michael Lebens, Ann-Mari Svennerholm
Vaccine - 2010 -
Construction and expression of immunogenic hybrid enterotoxigenic Escherichia coli CFA/I and CS2 colonization fimbriae for use in
vaccines.
Joshua Tobias, Ann-Mari Svennerholm, Jan Holmgren, Michael Lebens
Applied microbiology and biotechnology - 2010 -
BAFF, stimulatory DNA and IL-15 stimulates IgA(+) memory B cells and provides a novel approach for analysis of memory responses to mucosal
vaccines.
Sara Tengvall, Anna Lundgren, Marianne Quiding-Järbrink, Ann-Mari Svennerholm
Vaccine - 2010 -
Concomitant enterotoxigenic Escherichia coli infection induces increased immune responses to Vibrio cholerae O1 antigens in patients with cholera in
Bangladesh.
Fahima Chowdhury, Yasmin A Begum, Mohammad Murshid Alam, Ashraful I Khan, Tanvir Ahmed, M Saruar Bhuiyan, Jason B Harris, Regina C LaRocque, Abu S G Faruque, Hubert Endtz, Edward T Ryan, Alejandro Cravioto, Ann-Mari Svennerholm, Stephen B Calderwood, Firdausi Qadri
Infection and immunity - 2010 -
Survival and gene expression of enterotoxigenic Escherichia coli during long-term incubation in sea water and
freshwater.
Åsa Lothigius, Åsa Sjöling, Ann-Mari Svennerholm, Ingrid Bölin
Journal of applied microbiology - 2010 -
Children with the Le(a+b-) blood group have increased susceptibility to diarrhea caused by enterotoxigenic Escherichia coli expressing colonization factor I group
fimbriae.
Tanvir Ahmed, Anna Lundgren, Mohammad Arifuzzaman, Firdausi Qadri, Susann Teneberg, Ann-Mari Svennerholm
Infection and immunity - 2009 -
Presence of high numbers of transcriptionally active Helicobacter pylori in vomitus from Bangladeshi patients suffering from acute
gastroenteritis.
Anders Janzon, Taufiqur Rahman Bhuiyan, Anna Lundgren, Firdausi Qadri, Ann-Mari Svennerholm, Åsa Sjöling
Helicobacter - 2009 -
Decreased IgA antibody production in the stomach of gastric adenocarcinoma
patients.
Marianne Quiding-Järbrink, Patrik Sundström, Anna Lundgren, Malin Hansson, Malin Bäckström, Camilla Johansson, Karin Enarsson, Michael Hermansson, Erik Johnsson, Ann-Mari Svennerholm
Clinical immunology - 2009 -
FOXP3-expressing CD4(+) T-cell numbers increase in areas of duodenal gastric metaplasia and are associated to CD4(+) T-cell aggregates in the duodenum of Helicobacter pylori-infected duodenal ulcer
patients.
Bert Kindlund, Åsa Sjöling, Malin Hansson, Anders Edebo, Lars-Erik Hansson, Henrik Sjövall, Ann-Mari Svennerholm, Samuel B Lundin
Helicobacter - 2009 -
Sulfatide recognition by colonization factor antigen CS6 from enterotoxigenic Escherichia
coli.
Lena Jansson, Joshua Tobias, Catharina Jarefjäll, Michael Lebens, Ann-Mari Svennerholm, Susann Teneberg
PloS one - 2009 -
Infection by Helicobacter pylori in Bangladeshi children from birth to two years: relation to blood group, nutritional status, and
seasonality.
Taufiqur Rahman Bhuiyan, Firdausi Qadri, Amit Saha, Ann-Mari Svennerholm
The Pediatric infectious disease journal - 2009 -
Failure to detect Helicobacter pylori DNA in drinking and environmental water in Dhaka, Bangladesh, using highly sensitive real-time PCR
assays.
Anders Janzon, Åsa Sjöling, Åsa Lothigius, Dilruba Ahmed, Firdausi Qadri, Ann-Mari Svennerholm
Applied and environmental microbiology - 2009 -
Safety and immunogenecity of the oral whole cell Virio cholerae O1 plus cholera toxin B subunit vaccine in Bangladeshi infants 6-18 months of age:interventions to improve responsivesness (Vaccine (in
press).
T Ahmed, Firdausi Qadri, Ann-Mari Svennerholm
In press - 2009 -
Enhanced immunogenicity of an oral inactivated cholera vaccine in infants in Bangladesh obtained by zinc supplementation and by temporary withholding
breast-feeding.
Tanvir Ahmed, Ann-Mari Svennerholm, Abdullah Al Tarique, Gazi N N Sultana, Firdausi Qadri
Vaccine - 2009 -
Vaccines against enterotoxigenic Escherichia coli
(ETEC).
Ann-Mari Svennerholm, G Glenn
New generation vaccines. 4th ed. Eds Levine MM et al. - 2009 -
Development of multiplex PCR assays for detection of enterotoxigenic Escherichia coli colonization factors and
toxins.
Claudia Rodas, Volga Iniguez, Firdausi Qadri, Gudrun Wiklund, Ann-Mari Svennerholm, Åsa Sjöling
Journal of clinical microbiology - 2009 -
Public health. The cholera crisis in
Africa.
S Bhattacharya, R Black, L Bourgeois, J Clemens, A Cravioto, J L Deen, Gordon Dougan, R Glass, R F Grais, M Greco, I Gust, Jan Holmgren, S Kariuki, P-H Lambert, M A Liu, I Longini, G B Nair, R Norrby, G J V Nossal, P Ogra, P Sansonetti, L von Seidlein, F Songane, Ann-Mari Svennerholm, D Steele, R Walker
Science (New York, N.Y.) - 2009 -
Phenotypic and genotypic analysis of enterotoxigenic Escherichia coli in samples obtained from Egyptian children presenting to referral
hospitals.
H I Shaheen, I A Abdel Messih, J D Klena, A Mansour, Z El-Wakkeel, T F Wierzba, J W Sanders, S B Khalil, D M Rockabrand, M R Monteville, P J Rozmajzl, Ann-Mari Svennerholm, R W Frenck
Journal of clinical microbiology - 2009 -
Robust gut associated vaccine-specific antibody-secreting cell responses are detected at the mucosal surface of Bangladeshi subjects after immunization with an oral killed bivalent V. cholerae O1/O139 whole cell cholera vaccine: comparison with other mucosal and systemic
responses.
Sohel Shamsuzzaman, Tanvir Ahmed, Kaiissar Mannoor, Yasmin Ara Begum, Pradip Kumar Bardhan, R Bradley Sack, David A Sack, Ann-Mari Svennerholm, Jan Holmgren, Firdausi Qadri
Vaccine - 2009 -
Vaccines against enterotoxigenic Escherichia
coli.
Ann-Mari Svennerholm, Joshua Tobias
Expert review of vaccines - 2008 -
Role of different genes in the CS6 operon for surface expression of Enterotoxigenic Escherichia coli colonization factor
CS6.
Joshua Tobias, Michael Lebens, Susanne Källgård, Matilda Nicklasson, Ann-Mari Svennerholm
Vaccine - 2008 -
Construction of non-toxic Escherichia coli and Vibrio cholerae strains expressing high and immunogenic levels of enterotoxigenic E. coli colonization factor I
fimbriae.
Joshua Tobias, Michael Lebens, Ingrid Bölin, Gudrun Wiklund, Ann-Mari Svennerholm
Vaccine - 2008 -
Mutations in the periplasmic chaperone leading to loss of surface expression of the colonization factor CS6 in enterotoxigenic Escherichia coli (ETEC) clinical
isolates.
Matilda Nicklasson, Åsa Sjöling, Michael Lebens, Joshua Tobias, Anders Janzon, Lars Brive, Ann-Mari Svennerholm
Microbial Pathogenesis - 2008 -
Determinants of responses to oral vaccines in developing
countries.
David A Sack, Firdausi Qadri, Ann-Mari Svennerholm
Ann Nestlé - 2008 -
Enterotoxigenic Escherichia coli is detectable in water samples from an endemic area by real-time
PCR.
Åsa Lothigius, Anders Janzon, Y Begum, Åsa Sjöling, F Qadri, Ann-Mari Svennerholm, Ingrid Bölin
Journal of applied microbiology - 2008 -
Mucosal immune responses against enterotoxigenic Escherichia coli (ETEC) in
humans
Ann-Mari Svennerholm, Firdausi Qadri
Immunity Against Mucosal Pathogens. Edited by Michael Vajdy. - 2008 -
Phenotypic and genotypic analysis of enterotoxigenic Escheria coli (ETEC) obtained from Egyptian children presenting to referral
hospitals.
H. I. Shaheen, JD Abdel-Messih, A Klena, Z Mansour, TF El-Wakkeel, SB Sanders, DM Kahlil, MR Rockabrand, P J Monteville, P. J. Rozmajzl, Ann-Mari Svennerholm, Stephen Savarino, Robert W Jr Frenck
J Clin Microbial - 2008 -
Vaccines against exterotoxigenic Escheria coli
(ETEC).
Ann-Mari Svennerholm, G Glenn
In New Generation Vaccines - 2008 -
Shifting prevalence of major diarrheal pathogens in patients seeking hospital care during floods in 1998, 2004, and 2007 in Dhaka,
Bangladesh.
Aaron M Harris, Fahima Chowdhury, Yasmin Ara Begum, Ashraful Islam Khan, Abu S G Faruque, Jason B Harris, Edward T Ryan, Alejandro Cravioto, Stephen B Calderwood, Firdausi Qadri, Ann-Mari Svennerholm
The American journal of tropical medicine and hygiene - 2008 -
Comparison of mucosal B- and T-cell responses in Helicobacter pylori-infected subjects in a developing and a developed
country.
Taufiqur Rahman Bhuiyan, Firdausi Qadri, Prodip Kumar Bardhan, Mian Mashhud Ahmad, Bert Kindlund, Ann-Mari Svennerholm, Anna Lundgren
FEMS immunology and medical microbiology - 2008 -
Comparative analyses of phenotypic and genotypic methods for detection of enterotoxigenic Escherichia coli (ETEC) toxins and colonization
factors
Åsa Sjöling, Gudrun Wiklund, Stephen Savarino, D. I. Cohen, Ann-Mari Svennerholm
J Clin Microbiol - 2007 -
The local and systemic T-cell response to Helicobacter pylori in gastric cancer patients is characterised by production of
interleukin-10.
Samuel B Lundin, Karin Enarsson, Bert Kindlund, Anna Lundgren, Erik Johnsson, Marianne Quiding-Järbrink, Ann-Mari Svennerholm
Clinical immunology (Orlando, Fla.) - 2007 -
Disease burden due to enterotoxigenic Escherichia coli in the first 2 years of life in an urban community in
Bangladesh.
Firdausi Qadri, Amit Saha, Tanvir Ahmed, Abdullah Al Tarique, Yasmin Ara Begum, Ann-Mari Svennerholm
Infection and immunity - 2007 -
Oral immunization with HpaA affords therapeutic protective immunity against H. pylori that is reflected by specific mucosal immune
responses.
Johanna Nyström, Ann-Mari Svennerholm
Vaccine - 2007 -
Characterization of enterotoxigenic Escherichia coli from diarrhoeal patients in Bangladesh using phenotyping and genetic
profiling
M. Ansaruzzaman, N. A. Bhuiyan, Y. A. Begum, I. Kuhn, G. B. Nair, D. A. Sack, Ann-Mari Svennerholm, Firdausi Qadri
J Med Microbiol - 2007 -
Comparison of enterotoxigenic Escherichia coli isolated from surface water and diarrhoeal stool samples in
Bangladesh
Y. A. Begum, K. A. Talukder, G. B. Nair, S. I. Khan, Ann-Mari Svennerholm, R. B. Sack, Firdausi Qadri
Can J Microbiol - 2007 -
Immunoprophylaxis and Immunologic
control.
M M Levine, Ann-Mari Svennerholm
Textbook of Travel medicine and Health, 3rd edition, C Ericsson et al, eds Chapter 23 - 2007 -
Mucosal and systemic immune responses in patients with diarrhea due to CS6-expressing enterotoxigenic Escherichia
coli.
Firdausi Qadri, Tanvir Ahmed, Firoz Ahmed, M Saruar Bhuiyan, Mohammad Golam Mostofa, Frederick J Cassels, Anna Helander, Ann-Mari Svennerholm
Infection and immunity - 2007 -
Randomised, double-blind, safety and efficacy of a killed oral vaccine for enterotoxigenic E. Coli diarrhoea of travellers to Guatemala and
Mexico
D. A. Sack, J. Shimko, Olga Torres, A. L. Bourgeois, D. S. Francia, B. Gustafsson, Anders Kärnell, Iréne Nyquist, Ann-Mari Svennerholm
Vaccine - 2007 -
Progress in vaccine development against Helicobacter
pylori.
Ann-Mari Svennerholm, Anna Lundgren
FEMS immunology and medical microbiology - 2007 -
The major subunit, CfaB, of colonization factor antigen i from enterotoxigenic Escherichia coli is a glycosphingolipid binding
protein.
Lena Jansson, Joshua Tobias, Michael Lebens, Ann-Mari Svennerholm, Susann Teneberg
Infection and immunity - 2006 -
Differential mechanisms for T lymphocyte recruitment in normal and neoplastic human gastric
mucosa
Karin Enarsson, Erik Johnsson, Catharina Lindholm, Anna Lundgren, Q. Pan-Hammarström, Erika Strömberg, Philip Bergin, E. L. Baunge, Ann-Mari Svennerholm, Marianne Quiding-Järbrink
Clin Immunol - 2006 -
Characterization of the outer membrane protein profile from disease-related Helicobacter pylori isolates by subcellular fractionation and nano-LC FT-ICR MS
analysis
Elisabet Carlsohn, Johanna Nyström, Hasse Karlsson, Ann-Mari Svennerholm, Carol L Nilsson
J Proteome Res - 2006 -
Mucosal immune responses are related to reduction of bacterial colonization in the stomach after therapeutic Helicobacter pylori immunization in
mice
Johanna Nyström, Sukanya Raghavan, Ann-Mari Svennerholm
Microbes Infect - 2006 -
Engineered bacterial toxin vaccines and adjuvants InSourcebook of bacterial proteins,3rded Alouf&Popoff MR (eds) (in
press).
Jan Holmgren, Ann-Mari Svennerholm
3rded Alouf J &Popoff MR - 2006 -
Homologous and cross-reactive immune responses to enterotoxigenic Escherichia coli colonization factors in Bangladeshi
children.
Firdausi Qadri, Firoz Ahmed, Tanvir Ahmed, Ann-Mari Svennerholm
Infection and immunity - 2006 -
Enterotoxigenic Escherichia coli with STh and STp genotypes is associated with diarrhea both in children in areas of endemicity and in
travelers.
Ingrid Bölin, Gudrun Wiklund, Firdausi Qadri, Olga Torres, A Louis Bourgeois, Stephen Savarino, Ann-Mari Svennerholm
Journal of clinical microbiology - 2006 -
Reduced doses of oral killed enterotoxigenic Escherichia coli plus cholera toxin B subunit vaccine is safe and immunogenic in Bangladeshi infants 6-17 months of age: dosing studies in different age
groups
Firdausi Qadri, T. Ahmed, F. Ahmed, Y. A. Begum, D. A. Sack, Ann-Mari Svennerholm
Vaccine - 2006 -
HpaA is essential for Helicobacter pylori colonization in
mice
Elisabet Carlsohn, Johanna Nyström, Ingrid Bölin, Carol L Nilsson, Ann-Mari Svennerholm
Infect Immun - 2006 -
Breast milk reduces the risk of illness in children of mothers with cholera: observations from an epidemic of cholera in
Guinea-Bissau
K. Qureshi, K. Molbak, A. Sandstrom, P. E. Kofoed, A. Rodrigues, F. Dias, P. Aaby, Ann-Mari Svennerholm
Pediatr Infect Dis J - 2006 -
Enterotoxigenic Escherichia coli colonization factor types collected from 1997 to 2001 in US military personnel during operation Bright Star in northern
Egypt.
David M Rockabrand, Hind I Shaheen, Sami B Khalil, Leonard F Peruski, Patrick J Rozmajzl, Stephen J Savarino, Marshall R Monteville, Robert W Frenck, Ann-Mari Svennerholm, Shannon D Putnam, John W Sanders
Diagnostic microbiology and infectious disease - 2006 -
In vivo expression of the heat stable (estA) and heat labile (eltB) toxin genes of enterotoxigenic Escherichia coli
(ETEC).
Åsa Sjöling, Firdausi Qadri, Matilda Nicklasson, Yasmin Ara Begum, Gudrun Wiklund, Ann-Mari Svennerholm
Microbes and infection / Institut Pasteur - 2006 -
Cholera due to altered El Tor strains of Vibrio cholerae O1 in
Bangladesh.
G Balakrish Nair, Firdausi Qadri, Jan Holmgren, Ann-Mari Svennerholm, Ashrafus Safa, Nurul A Bhuiyan, Q Shafi Ahmad, Shah M Faruque, A S G Faruque, Yoshifumi Takeda, David A Sack
Journal of clinical microbiology - 2006 -
Dendritic cells express CCR7 and migrate in response to CCL19 (MIP-3beta) after exposure to Helicobacter
pylori
Malin Hansson, Anna Lundgren, Kristina Elgbratt, Marianne Quiding-Järbrink, Ann-Mari Svennerholm, Eva-Liz Johansson
Microbes Infect - 2006 -
Reduction in capsular content and enhanced bacterial susceptibility to serum killing of Vibrio cholerae O139 associated with the 2002 cholera epidemic in
Bangladesh
Firdausi Qadri, Ann-Mari Svennerholm, S. Shamsuzzaman, Taufiqur Rahman Bhuiyan, J. B. Harris, A. N. Ghosh, G. B. Nair, Andrej Weintraub, S. M. Faruque, E. T. Ryan, D. A. Sack, S. B. Calderwood
Infect Immun - 2005 -
Mucosal adjuvants and anti-infection and anti-immunopathology vaccines based on cholera toxin, cholera toxin B subunit and CpG
DNA
Jan Holmgren, Jenni Adamsson, F. Anjuere, J. Clemens, C. Czerkinsky, Kristina Eriksson, Carl-Fredrik Flach, Annie George-Chandy, Ali M Harandi, Michael Lebens, T. Lehner, Marianne Lindblad, Erik Nygren, Sukanya Raghavan, Joaquin Sanchez, M. Stanford, Jia-Bin Sun, Ann-Mari Svennerholm, Sara Tengvall
Immunol Lett - 2005 -
Helicobacter pylori induce neutrophil transendothelial migration: role of the bacterial
HP-NAP
Mikael Brisslert, Karin Enarsson, Samuel B Lundin, Anna Karlsson, J. G. Kusters, Ann-Mari Svennerholm, S. Backert, Marianne Quiding-Järbrink
FEMS Microbiol Lett - 2005 -
Natural killer cells and Helicobacter pylori infection: bacterial antigens and interleukin-12 act synergistically to induce gamma interferon
production
C. H. Yun, Anna Lundgren, Josef Azem, Åsa Sjöling, Jan Holmgren, Ann-Mari Svennerholm, Samuel B Lundin
Infect Immun - 2005 -
Serologic correlates of protection against enterotoxigenic Escherichia coli
diarrhea
Malla Rao, Thomas Wierzba, Stephen Savarino, Remon Abu-Elyazeed, N. El-Ghoreb, E. R. Hall, Abdollah Naficy, I. Abdel-Messih, Robert W Jr Frenck, Ann-Mari Svennerholm, John Clemens
J Infect Dis - 2005 -
Enterotoxigenic Escherichia coli isolated from surface water in urban and rural areas of
Bangladesh
Y. A. Begum, K. A. Talukder, G. B. Nair, F Qadri, R. B. Sack, Ann-Mari Svennerholm
J Clin Microbiol - 2005 -
Down-regulation of epithelial IL-8 responses in Helicobacter pylori-infected duodenal ulcer patients depends on host factors, rather than bacterial
factors
Erika Strömberg, Anders Edebo, Samuel B Lundin, Philip Bergin, Mikael Brisslert, Ann-Mari Svennerholm, Catharina Lindholm
Clin Exp Immunol - 2005 -
Helicobacter pylori-specific CD4+ T cells home to and accumulate in the human Helicobacter pylori-infected gastric
mucosa
Anna Lundgren, C. Trollmo, Anders Edebo, Ann-Mari Svennerholm, Samuel B Lundin
Infect Immun - 2005 -
Mucosal FOXP3-expressing CD4+ CD25high regulatory T cells in Helicobacter pylori-infected
patients
Anna Lundgren, Erika Strömberg, Åsa Sjöling, Catharina Lindholm, Karin Enarsson, Anders Edebo, Erik Johnsson, Elisabeth Suri-Payer, Pia Larsson, Anna Rudin, Ann-Mari Svennerholm, Samuel B Lundin
Infect Immun - 2005 -
B cells pulsed with Helicobacter pylori antigen efficiently activate memory CD8+ T cells from H. pylori-infected
individuals
Josef Azem, Ann-Mari Svennerholm, Samuel B Lundin
Clin Immunol - 2005 -
Enterotoxigenic Escherichia coli and Vibrio cholerae diarrhea, Bangladesh,
2004
F. Qadri, A. I. Khan, A. S. Faruque, Y. A. Begum, F. Chowdhury, G. B. Nair, M. A. Salam, D. A. Sack, Ann-Mari Svennerholm
Emerg Infect Dis - 2005 -
Enterotoxigenic Escherichia coli in developing countries: epidemiology, microbiology, clinical features, treatment, and
prevention
Firdausi Qadri, Ann-Mari Svennerholm, A. S. Faruque, R. B. Sack
Clin Microbiol Rev - 2005 -
Development of pathogenicity-driven definitions of outcomes for a field trial of a killed oral vaccine against enterotoxigenic Escherichia coli in Egypt: application of an evidence-based
method
John Clemens, Stephen Savarino, Remon Abu-Elyazeed, Mohammad Safwat, Malla Rao, Thomas Wierzba, Ann-Mari Svennerholm, Jan Holmgren, Robert Frenck, Eunsik Park, Abdollah Naficy
J Infect Dis - 2004 -
Detection of antibodies to toxin-coregulated pili in sera from cholera
patients
Stephen Attridge, Gun Wallerström, Firdausi Qadri, Ann-Mari Svennerholm
Infect Immun - 2004 -
Microbial-gut interactions in health and disease. Progress in enteric vaccine
development.
Ann-Mari Svennerholm, Duncan Steele
Best practice & research. Clinical gastroenterology - 2004 -
Comparison of different routes of vaccination for eliciting antibody responses in the human
stomach
Eva-Liz Johansson, Charlotta Bergquist, Anders Edebo, Camilla Johansson, Ann-Mari Svennerholm
Vaccine - 2004 -
Acute dehydrating disease caused by Vibrio cholerae serogroups O1 and O139 induce increases in innate cells and inflammatory mediators at the mucosal surface of the
gut
F Qadri, T. R. Bhuiyan, K. K. Dutta, R. Raqib, M. S. Alam, N. H. Alam, Ann-Mari Svennerholm, M. M. Mathan
Gut - 2004 -
Phenotypic profiles of enterotoxigenic Escherichia coli associated with early childhood diarrhea in rural
Egypt
H. I. Shaheen, S. B. Khalil, Malla Rao, R. Abu Elyazeed, Thomas Wierzba, L. F., Jr. Peruski, S. Putnam, A. Navarro, B. Z. Morsy, A. Cravioto, John Clemens, Ann-Mari Svennerholm, Stephen Savarino
J Clin Microbiol - 2004 -
Binding of enterotoxigenic Escherichia coli to isolated enterocytes and intestinal
mucus.
A Helander, Gunnar C. Hansson, Ann-Mari Svennerholm
Microbial pathogenesis - 1997 -
Binding of human enterotoxigenic Escherichia coli expressing coli surface antigen 6 to rabbit intestinal enterocytes and
glycoproteins.
Anna Helander, Gunnar C. Hansson, Ann-Mari Svennerholm
Advances in experimental medicine and biology - 1997 -
Adhesins of Escherichia coli associated with extra-intestinal pathogenicity confer binding to colonic epithelial
cells.
Ingegerd Adlerberth, Lars Åke Hanson, Catharina Svanborg, Ann-Mari Svennerholm, Svante Nordgren, Agnes E Wold
Microbial pathogenesis - 1995 -
Inhibited growth of common enteropathogenic bacteria in lactic-fermented cereal
gruels
Ulf Svanberg, Eva Sjögren, Wilbald S.M. Lorri, Ann-Mari Svennerholm, Bertil Kaijser
World Journal of Microbiology & Biotechnology - 1992