Piero Pingitore
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LPIAT1/MBOAT7 contains a catalytic dyad transferring polyunsaturated fatty acids to
lysophosphatidylinositol.
Andrea Caddeo, Kristina Hedfalk, Stefano Romeo, Piero Pingitore
Biochimica et biophysica acta. Molecular and cell biology of lipids - 2021-01-01 -
Discovery and Targeting of the Signaling Controls of PNPLA3 to Effectively Reduce Transcription, Expression, and Function in Pre-Clinical NAFLD/NASH
Settings
B. E. Schwartz, V. Rajagopal, C. Smith, E. Cohick, G. Whissell, M. Gamboa, R. Pai, A. Sigova, I. Grossman, D. Bumcrot, Kavitha Sasidharan, Stefano Romeo, A. Sehgal, Piero Pingitore
Cells - 2020-01-01 -
MBOAT7 is anchored to endomembranes by six transmembrane
domains.
Andrea Caddeo, Jamialahmadi Oveis, Giovanni Solinas, Puija Arturo, Rosellina Margherita Mancina, Piero Pingitore, Stefano Romeo
Journal of structural biology - 2019-01-01 -
Human Multilineage 3D Spheroids as a Model of Liver Steatosis and
Fibrosis.
Piero Pingitore, Kavitha Sasidharan, Matias Ekstrand, Sebastian Prill, Daniel Lindén, Stefano Romeo
International journal of molecular sciences - 2019-01-01 -
The TM6SF2 E167K genetic variant induces lipid biosynthesis and reduces apolipoprotein B secretion in human hepatic 3D
spheroids
S. Prill, Andrea Caddeo, G. Baselli, Jamialahmadi Oveis, P. Dongiovanni, R. Rametta, K. P. Kanebratt, A. Pujia, Piero Pingitore, Rosellina Margherita Mancina, D. Linden, C. Whatling, A. Janefeldt, M. Kozyra, M. Ingelman-Sundberg, L. Valenti, T. B. Andersson, S. Romeo
Scientific Reports - 2019-01-01 -
Pnpla3 silencing with antisense oligonucleotides ameliorates nonalcoholic steatohepatitis and fibrosis in Pnpla3 I148M knock-in
mice.
Daniel Lindén, Andrea Ahnmark, Piero Pingitore, Ester Ciociola, Ingela Ahlstedt, Anne-Christine Andréasson, Kavitha Sasidharan, Katja Madeyski-Bengtson, Magdalena Zurek, Rosellina Margherita Mancina, Anna Lindblom, Mikael Bjursell, Gerhard Böttcher, Marcus Ståhlman, Mohammad Bohlooly-Yeganeh, William G Haynes, Björn Carlsson, Mark Graham, Richard Lee, Sue Murray, Luca Valenti, Sanjay Bhanot, Peter Åkerblad, Stefano Romeo
Molecular metabolism - 2019-01-01 -
The role of PNPLA3 in health and
disease.
Piero Pingitore, Stefano Romeo
Biochimica et biophysica acta - 2019-01-01 -
Deciphering the role of V200A and N291S mutations leading to LPL
deficiency.
Botta M, Maurere E, Ruscica M, Stefano Romeo, Stulnig TM, Piero Pingitore
Atherosclerosis - 2019-01-01 -
Cys Site-Directed Mutagenesis of the Human SLC1A5 (ASCT2) Transporter: Structure/Function Relationships and Crucial Role of Cys467 for Redox Sensing and Glutamine
Transport
M. Scalise, L. Pochini, L. Console, G. Pappacoda, Piero Pingitore, Kristina Hedfalk, C. Indiveri
International Journal of Molecular Sciences - 2018-01-01 -
Causal relationship of hepatic fat with liver damage and insulin resistance in nonalcoholic fatty
liver.
P Dongiovanni, S Stender, A Pietrelli, Rosellina Margherita Mancina, A Cespiati, S Petta, S Pelusi, Piero Pingitore, S Badiali, M Maggioni, V Mannisto, S Grimaudo, R M Pipitone, J Pihlajamaki, A Craxi, Magdalena Taube, Lena M S Carlsson, S Fargion, Stefano Romeo, J Kozlitina, L Valenti
Journal of internal medicine - 2018-01-01 -
Molecular analysis of three known and one novel LPL variants in patients with type I
hyperlipoproteinemia.
Andrea Caddeo, Rosellina Margherita Mancina, Carlo Pirazzi, C. Russo, Kavitha Sasidharan, Joakim Sandstedt, S. Maurotti, T. Montalcini, A. Pujia, T. P. Leren, Stefano Romeo, Piero Pingitore
Nutrition, metabolism, and cardiovascular diseases : NMCD - 2018-01-01 -
Analysis of aquaporins from the euryhaline barnacle Balanus improvisus reveals differential expression in response to changes in
salinity
Ulrika Lind, Michael Järvå, Magnus Alm Rosenblad, Piero Pingitore, Emil Karlsson, Anna Lisa Wrange, Emelie Kamdal, Kristina Sundell, Carl André, Per R. Jonsson, Jonathan N. Havenhand, Leif A Eriksson, Kristina Hedfalk, Anders Blomberg
PLoS ONE - 2017-01-01 -
Proinsulin C-peptide modulates the expression of ERK1/2, type I collagen and RANKL in human osteoblast-like cells
(Saos-2).
Cristina Russo, Veronica Lazzaro, Carmine Gazzaruso, Samantha Maurotti, Yvelise Ferro, Piero Pingitore, Francesca Fumo, Adriana Coppola, Pietro Gallotti, Valentina Zambianchi, Mariangela Fodaro, Emanuela Galliera, Monica Gioia Marazzi, Massimiliano Marco Corsi Romanelli, Sandro Giannini, Stefano Romeo, Arturo Pujia, Tiziana Montalcini
Molecular and cellular endocrinology - 2017-01-01 -
Telomerase reverse transcriptase germline mutations and hepatocellular carcinoma in patients with nonalcoholic fatty liver
disease.
Benedetta Donati, Alessandro Pietrelli, Piero Pingitore, Paola Dongiovanni, Andrea Caddeo, Lucy Walker, Guido Baselli, Serena Pelusi, Chiara Rosso, Ester Vanni, Ann Daly, Rosellina Margherita Mancina, Antonio Grieco, Luca Miele, Stefania Grimaudo, Antonio Craxi, Salvatore Petta, Laura De Luca, Silvia Maier, Giorgio Soardo, Elisabetta Bugianesi, Fabio Colli, Renato Romagnoli, Quentin M Anstee, Helen L Reeves, Anna Ludovica Fracanzani, Silvia Fargion, Stefano Romeo, Luca Valenti
Cancer medicine - 2017-01-01 -
PNPLA3 overexpression results in reduction of proteins predisposing to
fibrosis.
Piero Pingitore, Paola Dongiovanni, Benedetta Maria Motta, Marica Meroni, Saverio Massimo Lepore, Rosellina Margherita Mancina, Serena Pelusi, Cristina Russo, Andrea Caddeo, Giorgio Rossi, Tiziana Montalcini, Arturo Pujia, Olov Wiklund, Luca Valenti, Stefano Romeo
Human molecular genetics - 2016-01-01 -
The rs2294918 E434K variant modulates PNPLA3 expression and liver
damage.
Benedetta Donati, Benedetta Maria Motta, Piero Pingitore, Marica Meroni, Alessandro Pietrelli, Anna Alisi, Salvatore Petta, Chao Xing, Paola Dongiovanni, Benedetta Del Menico, Raffaela Rametta, Rosellina Margherita Mancina, Sara Badiali, Anna Ludovica Fracanzani, Antonio Craxì, Silvia Fargion, Valerio Nobili, Stefano Romeo, Luca Valenti
Hepatology (Baltimore, Md.) - 2016-01-01 -
The MBOAT7-TMC4 Variant rs641738 Increases Risk of Nonalcoholic Fatty Liver Disease in Individuals of European
Descent.
Rosellina Margherita Mancina, Paola Dongiovanni, Salvatore Petta, Piero Pingitore, Marica Meroni, Raffaela Rametta, Jan Borén, Tiziana Montalcini, Arturo Pujia, Olov Wiklund, George Hindy, Rocco Spagnuolo, Benedetta Maria Motta, Rosaria Maria Pipitone, Antonio Craxì, Silvia Fargion, Valerio Nobili, Pirjo Käkelä, Vesa Kärjä, Ville Männistö, Jussi Pihlajamäki, Dermot F Reilly, Jose Castro-Perez, Julia Kozlitina, Luca Valenti, Stefano Romeo
Gastroenterology - 2016-01-01 -
Identification and characterization of two novel mutations in the LPL gene causing type I
hyperlipoproteinemia.
Piero Pingitore, Saverio Massimo Lepore, Carlo Pirazzi, Rosellina Margherita Mancina, Benedetta Maria Motta, Luca Valenti, Knut Erik Berge, Kjetil Retterstøl, Trond P Leren, Olov Wiklund, Stefano Romeo
Journal of clinical lipidology - 2016-01-01 -
PNPLA3 148M Carriers with Inflammatory Bowel Diseases Have Higher Susceptibility to Hepatic Steatosis and Higher Liver
Enzymes
Rosellina Margherita Mancina, R. Spagnuolo, M. Milano, S. Brogneri, A. Morrone, C. Cosco, V. Lazzaro, C. Russo, Y. Ferro, Piero Pingitore, A. Pujia, T. Montalcini, P. Doldo, P. Garieri, L. Piodi, F. Caprioli, L. Valenti, Stefano Romeo
Inflammatory Bowel Diseases - 2016-01-01 -
DEPDC5 variants increase fibrosis progression in Europeans with chronic HCV
infection.
Maria Antonella Burza, Benedetta Maria Motta, Rosellina Margherita Mancina, Piero Pingitore, Carlo Pirazzi, Saverio Massimo Lepore, Rocco Spagnuolo, Patrizia Doldo, Cristina Russo, Veronica Lazzaro, Janett Fischer, Thomas Berg, Alessio Aghemo, Cristina Cheroni, Raffaele De Francesco, Silvia Fargion, Massimo Colombo, Christian Datz, Felix Stickel, Luca Valenti, Stefano Romeo
Hepatology (Baltimore, Md.) - 2016-01-01 -
Cysteine is not a substrate but a specific modulator of human ASCT2 (SLC1A5)
transporter.
Mariafrancesca Scalise, Lorena Pochini, Piero Pingitore, Kristina Hedfalk, Cesare Indiveri
FEBS letters - 2015-01-01 -
Recombinant PNPLA3 protein shows triglyceride hydrolase activity and its I148M mutation results in loss of
function.
Piero Pingitore, Carlo Pirazzi, Rosellina Margherita Mancina, Benedetta Maria Motta, Cesare Indiveri, Arturo Pujia, Tiziana Montalcini, Kristina Hedfalk, Stefano Romeo
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids - 2014-01-01 -
Transport mechanism and regulatory properties of the human amino acid transporter ASCT2
(SLC1A5).
Mariafrancesca Scalise, Lorena Pochini, Simona Panni, Piero Pingitore, Kristina Hedfalk, Cesare Indiveri
Amino acids - 2014-01-01 -
PNPLA3 has retinyl-palmitate lipase activity in human hepatic stellate
cells
Carlo Pirazzi, L. Valenti, Benedetta Maria Motta, Piero Pingitore, Kristina Hedfalk, Rosellina Margherita Mancina, Maria Antonella Burza, C. Indiveri, Y. Ferro, T. Montalcini, Cristina Maglio, P. Dongiovanni, S. Fargion, R. Rametta, A. Pujia, Linda Andersson, Saswati Ghosal, Malin Levin, Olov Wiklund, M. Iacovino, Jan Borén, Stefano Romeo
Human Molecular Genetics - 2014-01-01 -
Large scale production of the active human ASCT2 (SLC1A5) transporter in Pichia pastoris - functional and kinetic asymmetry revealed in
proteoliposomes
Piero Pingitore, L. Pochini, M. Scalise, M. Galluccio, Kristina Hedfalk, C. Indiveri
Biochimica Et Biophysica Acta-Biomembranes - 2013-01-01