Kristina M Adams Waldorf
Om Kristina M Adams Waldorf
About Kristina Adams Waldorf Researchfield: Microbiology; Immunology; Prenatal and Perinatal Research; Translational and clinical research Research areas - Medical and Health Sciences
- Basic Medicine
Cell and Molecular Biology Microbiology in the medical area Microbiology Clinical bacteriology Immunology in the medical area
- Clinical Medicine
Rheumatology and Autoimmunity Obstetrics, Gynecology and Reproductive Medicine Obstetrics and women's diseases Obstetrics and gynaecology Reproductive and perinatal care Pediatrics
- Other Medical Sciences
Other Medical Sciences not elsewhere specified Prenatal and perinatal research
Current research Her research interests have focused on infections in pregnancy, preterm birth and fetal injury related to Group B Streptococcus, E. coli and more recently, the Zika virus. Her laboratory is actively investigating the following areas: 1) virulence and host factors that contribute to bacterial and viral trafficking into the amniotic cavity and fetus, 2) how activation of innate immune responses by pathogens within the placenta and fetus contributes to pregnancy complications and fetal injury, 3) how disruption of maternal-fetal tolerance by pathogens contributes to preterm birth, and 4) the role of novel therapeutics to prevent preterm birth and fetal injury due to pathogens. She is also studying the long-term outcomes of infections in pregnancy in Scandinavian health registries.
Main topics: 1. Pregnancy infections 2. Preterm birth 3. Fetal brain and lung injury 4. Placenta 5. Developmental origins of health and disease.
Financier: National Institutes of Health Burroughs Wellcome Fund March of Dimes
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Non-human Primate Models to Investigate Mechanisms of Infection-Associated Fetal and Pediatric Injury, Teratogenesis and
Stillbirth
M. Li, A. Brokaw, A. M. Furuta, B. Coler, V. Obregon-Perko, A. Chahroudi, H. Y. Wang, S. R. Permar, C. E. Hotchkiss, T. G. Golos, L. Rajagopal, Kristina M. Adams Waldorf
Frontiers in Genetics - 2021-01-01 -
Amniotic fluid interleukin 6 and interleukin 8 are superior predictors of fetal lung injury compared with maternal or fetal plasma cytokines or placental histopathology in a nonhuman primate
model
S. A. McCartney, R. Kapur, H. D. Liggitt, A. Baldessari, M. Coleman, A. Orvis, J. Ogle, R. Katz, L. Rajagopal, Kristina M. Adams Waldorf
American Journal of Obstetrics and Gynecology - 2021-01-01 -
Low Prevalence of Severe Acute Respiratory Syndrome Coronavirus 2 Among Pregnant and Postpartum Patients With Universal Screening in Seattle,
Washington
S. M. LaCourse, A. Kachikis, M. Blain, L. E. Simmons, J. A. Mays, A. D. Pattison, C. C. Salerno, S. A. McCartney, N. M. Kretzer, R. Resnick, R. L. Shay, L. M. Savitsky, A. C. Curtin, E. M. Huebner, K. K. Ma, S. Delaney, C. Delgado, A. Schippers, J. Munson, P. S. Pottinger, S. Cohen, S. Neme, L. Bourassa, A. Bryan, A. Greninger, K. R. Jerome, A. C. Roxby, E. Lokken, E. Cheng, Kristina M. Adams Waldorf, J. Hitti
Clinical Infectious Diseases - 2021-01-01 -
Hyaluronidase Impairs Neutrophil Function and Promotes Group B Streptococcus Invasion and Preterm Labor in Nonhuman
Primates
M. Coleman, B. Armistead, A. Orvis, P. Quach, A. Brokaw, C. Gendrin, K. Sharma, J. Ogle, S. Merillat, M. Dacanay, T. Y. Wu, J. Munson, A. Baldessari, J. Vornhagen, A. Furuta, S. Nguyen, Kristina M. Adams Waldorf, L. Rajagopal
Mbio - 2021-01-01 -
Importance of inclusion of pregnant and breastfeeding women in COVID-19 therapeutic
trials
S. M. LaCourse, G. John-Stewart, Kristina M. Adams Waldorf
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America - 2020-01-01 -
Mid-trimester amniotic fluid proteome's association with spontaneous preterm delivery and gestational
duration.
Maria Hallingström, Petra Zedníková, Vojtěch Tambor, Malin Barman, Marie Vajrychová, Juraj Lenčo, Felicia Viklund, Linda Tancred, Hardis Rabe, Daniel Jonsson, Alisa Kachikis, Staffan Nilsson, Marian Kacerovský, Kristina M. Adams Waldorf, Bo Jacobsson
PloS one - 2020-01-01 -
Ultrasound prediction of Zika virus-associated congenital injury using the profile of fetal
growth
C. L. Walker, N. Ehinger, B. Mason, E. Oler, M. T. E. Little, E. O. Ohuma, A. T. Papageorghiou, U. Nayeri, C. Curry, Kristina M. Adams Waldorf
PLoS ONE - 2020-01-01 -
Lipid analogs reveal features critical for hemolysis and diminish granadaene mediated Group B Streptococcus
infection
B. Armistead, P. Herrero-Foncubierta, M. Coleman, P. Quach, C. Whidbey, J. Justicia, R. Tapia, R. Casares, A. Millan, A. Haidour, J. R. Granger, J. Vornhagen, V. Santana-Ufret, S. Merillat, Kristina M. Adams Waldorf, J. M. Cuerva, L. Rajagopal
Nature Communications - 2020-01-01 -
The fetal origins of mental
illness.
Benjamin J S Al-Haddad, Elizabeth Oler, Blair Armistead, Nada A Elsayed, Daniel R Weinberger, Raphael Bernier, Irina Burd, Raj Kapur, Bo Jacobsson, Caihong Wang, Indira Mysorekar, Lakshmi Rajagopal, Kristina M. Adams Waldorf
American journal of obstetrics and gynecology - 2019-01-01 -
Immune Evasion Strategies Used by Zika Virus to Infect the Fetal Eye and
Brain
B. R. Nelson, J. A. Roby, W. B. Dobyns, L. Rajagopa, M. Gale, Kristina M. Adams Waldorf
Viral Immunology - 2019-01-01 -
The Double Life of Group B Streptococcus: Asymptomatic Colonizer and Potent
Pathogen
B. Armistead, E. Oler, Kristina M. Adams Waldorf, L. Rajagopal
Journal of Molecular Biology - 2019-01-01 -
Long-term Risk of Neuropsychiatric Disease After Exposure to Infection In
Utero.
Benjamin J S Al-Haddad, Bo Jacobsson, Shilpi Chabra, Dominika Modzelewska, Erin M Olson, Raphael Bernier, Daniel A Enquobahrie, Henrik Hagberg, Svante Östling, Lakshmi Rajagopal, Kristina M. Adams Waldorf, Verena Sengpiel
JAMA psychiatry - 2019-01-01 -
Zika virus and the nonmicrocephalic fetus: why we should still
worry
C. L. Walker, M. T. E. Little, J. A. Roby, B. Armistead, M. Gale, L. Rajagopal, B. R. Nelson, N. Ehinger, B. Mason, U. Nayeri, C. L. Curry, Kristina M. Adams Waldorf
American Journal of Obstetrics and Gynecology - 2019-01-01 -
Evidence of cardiac involvement in the fetal inflammatory response syndrome: disruption of gene networks programming cardiac development in nonhuman
primates
T. Mitchell, J. W. MacDonald, S. Srinouanpranchanh, T. K. Bammler, S. Merillat, E. Boldenow, M. Coleman, K. Agnew, A. Baldessari, J. E. Stencel-Baerenwald, J. Tisoncik-Go, R. R. Green, M. J. Gale, L. Rajagopal, Kristina M. Adams Waldorf
American Journal of Obstetrics and Gynecology - 2018-01-01 -
Femur-sparing pattern of abnormal fetal growth in pregnant women from New York City after maternal Zika virus
infection
C. L. Walker, A. A. Merriam, E. O. Ohuma, M. K. Dighe, M. Gale, L. Rajagopal, A. T. Papageorghiou, C. Gyamfi-Bannerman, Kristina M. Adams Waldorf
American Journal of Obstetrics and Gynecology - 2018-01-01 -
Group B streptococcus exploits vaginal epithelial exfoliation for ascending
infection
J. Vornhagen, B. Armistead, V. Santana-Ufret, C. Gendrin, S. Merillat, M. Coleman, P. Quach, E. Boldenow, V. Alishetti, C. Leonhard-Melief, L. Y. Ngo, C. Whidbey, K. S. Doran, C. Curtis, Kristina M. Adams Waldorf, E. Nance, L. Rajagopal
Journal of Clinical Investigation - 2018-01-01 -
Human Cervical Mucus Plugs Exhibit Insufficiencies in Antimicrobial Activity Towards Group B
Streptococcus
J. Vornhagen, P. Quach, V. Santana-Ufret, V. Alishetti, A. Brokaw, B. Armistead, H. Q. Tang, J. W. MacDonald, T. K. Bammler, Kristina M. Adams Waldorf, N. Uldbjerg, L. Rajagopal
Journal of Infectious Diseases - 2018-01-01 -
Congenital Zika virus infection as a silent pathology with loss of neurogenic output in the fetal
brain
Kristina M. Adams Waldorf, B. R. Nelson, J. E. Stencel-Baerenwald, C. Studholme, R. P. Kapur, B. Armistead, C. L. Walker, S. Merillat, J. Vornhagen, J. Tisoncik-Go, A. Baldessari, M. Coleman, M. K. Dighe, D. W. W. Shaw, J. A. Roby, V. Santana-Ufret, E. Boldenow, J. W. Li, X. H. Gao, M. A. Davis, J. A. Swanstrom, K. Jensen, D. G. Widman, R. S. Baric, J. T. Medwid, K. A. Hanley, J. Ogle, G. M. Gough, W. Lee, C. English, W. M. Durning, J. Thiel, C. Gatenby, E. C. Dewey, M. R. Fairgrieve, R. D. Hodge, R. F. Grant, L. Kuller, W. B. Dobyns, R. F. Hevner, M. Gale, L. Rajagopal
Nature Medicine - 2018-01-01 -
Dramatic enhancement of the detection limits of bioassays via ultrafast deposition of
polydopamine
J. Li, M. A. Baird, M. A. Davis, W. Tai, L. S. Zweifel, Kristina M. Adams Waldorf, Jr. Gale, L. Rajagopal, R. H. Pierce, X. Gao
Nature Biomedical Engineering - 2017-01-01 -
Perinatal Group B Streptococcal Infections: Virulence Factors, Immunity, and Prevention
Strategies
J. Vornhagen, Kristina M. Adams Waldorf, L. Rajagopal
Trends in Microbiology - 2017-01-01