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Dyslipidemia and high waist-hip ratio in women with self-reported social anxiety.

Artikel i vetenskaplig tidskrift
Författare Mikael Landén
Fariba Baghaei
Roland Rosmond
Göran Holm
Per Björntorp
Elias Eriksson
Publicerad i Psychoneuroendocrinology
Volym 29
Nummer/häfte 8
Sidor 1037-46
ISSN 0306-4530
Publiceringsår 2004
Publicerad vid Hjärt-kärlinstitutionen
Institutionen för klinisk neurovetenskap, Sektionen för psykiatri
Institutionen för fysiologi och farmakologi, Avdelningen för farmakologi
Sidor 1037-46
Språk en
Länkar dx.doi.org/10.1016/j.psyneuen.2003....
Ämnesord Adult, Anxiety Disorders, blood, epidemiology, Body Constitution, Body Mass Index, Cohort Studies, Comorbidity, Female, Humans, Hyperlipidemias, blood, epidemiology, Lipoproteins, blood, Self Assessment (Psychology), Social Environment, Sweden, epidemiology, Testosterone, blood, Thyroxine, blood, Triglycerides, blood
Ämneskategorier Fysiologi, Psykiatri

Sammanfattning

Previous research has indicated that phobic anxiety is associated with coronary heart disease. In this study, the possible association between social anxiety and various anthropometric, metabolic, and endocrine measurements known to be associated with cardiovascular disease were studied in a population-based cohort of 216 women 41-42 years old. Each participant was assessed by means of a DSM-IV based self-report questionnaire regarding social anxiety and related psychiatric diagnoses. Waist-to-hip ratio (WHR), body mass index (BMI), and serum levels of lipids and hormones were assessed. The prevalence of social anxiety was 14% (n=31). The social anxiety group displayed higher serum levels of triglycerides (1.3+/-0.9 vs. 1.0+/-0.5, P=0.003) and low-density lipoprotein (LDL) (3.3+/-0.8 vs. 3.0+/-0.7, P=0.03), but lower high-density lipoprotein (HDL) (1.4+/-0.3 vs. 1.6+/-0.4, P=0.04) and HDL/LDL ratio (0.46+/-0.15 vs. 0.57+/-0.22, P=0.008) than the other women. Serum levels of total testosterone (1.6+/-0.8 vs. 2.2+/-1.1, P=0.013) and free thyroxin (14+/-2 vs. 16+/-4, P=0.04) were lower in subjects confirming social anxiety. While WHR was significantly higher in the social anxiety group (0.83+/-0.06 vs. 0.80+/-0.07, P=0.016), BMI did not differ between the groups. Our data suggest that self-reported social anxiety is associated with two established risk factors for cardiovascular disease: dyslipidemia and increased WHR.

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