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Minor salivary gland secretion rates and immunoglobulin A in adults and the elderly.

Artikel i vetenskaplig tidskrift
Författare Lars Eliasson
Dowen Birkhed
Tor Österberg
Anette Carlén
Publicerad i European journal of oral sciences
Volym 114
Nummer/häfte 6
Sidor 494-9
ISSN 0909-8836
Publiceringsår 2006
Publicerad vid Institutionen för odontologi
Sidor 494-9
Språk en
Länkar dx.doi.org/10.1111/j.1600-0722.2006...
Ämnesord Adolescent, Adrenergic beta-Antagonists, pharmacology, Adult, Age Factors, Aged, Aged, 80 and over, Aging, physiology, Antihypertensive Agents, pharmacology, Female, Humans, Immunoglobulin A, Secretory, analysis, Male, Middle Aged, Pregnancy, Regression Analysis, Saliva, chemistry, immunology, secretion, Salivary Glands, Minor, drug effects, secretion, Secretory Rate, drug effects, Sex Factors, Smoking
Ämneskategorier Odontologi, Cariologi, Oral mikrobiologi

Sammanfattning

Previously published data are conflicting about the effect of various factors on secretions from minor salivary glands. The aim of the present study was to investigate the secretion rate from palatal, buccal, and labial glands, and to analyze the immunoglobulin A (IgA) concentrations in relation to age, gender, circulatory disease, diabetes, medication, smoking, and pregnancy. Resting and stimulated whole-saliva secretion rates, as well as IgA concentration in stimulated whole saliva, were also examined. One-hundred and forty two individuals (96 women and 46 men), 18-82 yr of age, participated. The results did not suggest any effect of aging on the secretion capacity of minor salivary glands, but the IgA concentration seemed to increase with age. Women had lower buccal and labial saliva secretion rates, and lower levels of IgA in buccal saliva, than men. For whole saliva, resting, but not stimulated, saliva secretion rates were reduced with age, and the secretion rate of stimulated whole saliva was lower in women than in men. The IgA concentration in buccal saliva showed a positive correlation with IgA in stimulated whole saliva, and the IgA concentration decreased with increased flow rate in both salivas.

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