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Ophthalmological findings in children born after intracytoplasmic sperm injection

Artikel i vetenskaplig tidskrift
Författare Margareta Hök Wikstrand
Kerstin Strömland
Sara Flodin
Christina Bergh
Ulla-Britt Wennerholm
Ann Hellström
Publicerad i Acta Ophthalmol Scand
Volym 84
Nummer/häfte 2
Sidor 177-81
Publiceringsår 2006
Publicerad vid Institutionen för neurovetenskap och fysiologi, sektionen för klinisk neurovetenskap och rehabilitering
Institutionen för kliniska vetenskaper
Sidor 177-81
Språk en
Länkar www.ncbi.nlm.nih.gov/entrez/query.f...
Ämnesord Case-Control Studies, Child, Preschool, Cognition/physiology, Female, Gestational Age, Humans, Intelligence/physiology, Male, Maternal Age, *Ocular Physiology, Refraction, Ocular/physiology, Refractive Errors/epidemiology, *Sperm Injections, Intracytoplasmic, Sweden/epidemiology, Vision Disorders/epidemiology, Vision Tests, Visual Acuity/*physiology
Ämneskategorier Medicin och Hälsovetenskap

Sammanfattning

PURPOSE: To investigate visual function and ocular morphology in children born after intracytoplasmic sperm injection (ICSI) and compare them with visual function and ocular morphology in matched children born after spontaneous conception. METHODS: A total of 137 children born after ICSI and 159 control children were examined at the age of 5 years in a blinded study. The two groups were matched for age, gender and maternal age. The children underwent a detailed ophthalmological investigation by an ophthalmologist and an orthoptist. RESULTS: A total of 90.4% of the ICSI children had a visual acuity (VA) in the better eye of >or= 0.8, compared with 93.7% of the controls (NS). No significant differences were found between ICSI children and controls with regard to hyperopia, myopia, astigmatism, heterotropia, stereoscopic vision and convergence. One child with Goldenhar syndrome and one with Marcus Gunn syndrome were observed in the ICSI group. One child in the ICSI group was treated for retinopathy of prematurity. CONCLUSION: In this limited study group, no significant differences in visual function and/or ocular morphology were found between children born after ICSI and matched control children at the age of 5 years.

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