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Non-Graft-versus-Host Disease Ocular Complications after Hematopoietic Cell Transplantation: Expert Review from the Late Effects and Quality of Life Working Committee of the Center for International Blood and Marrow Transplant Research and the Transplant Complications Working Party of the European Society for Blood and Marrow Transplantation

Artikel i vetenskaplig tidskrift
Författare Y. Inamoto
I. Petricek
L. Burns
S. Chhabra
Z. DeFilipp
P. Hematti
A. Rovo
R. Schears
A. Shah
V. Agrawal
A. Ahmed
I. Ahmed
A. Ali
M. Aljurf
H. Alkhateeb
A. Beitinjaneh
N. Bhatt
D. Buchbinder
M. Byrne
N. Callander
Kristina Teär Fahnehjelm
N. Farhadfar
R. P. Gale
S. Ganguly
S. Hashmi
G. C. Hildebrandt
E. Horn
A. Jakubowski
R. T. Kamble
J. Law
C. Lee
S. Nathan
O. Penack
R. Pingali
P. Prasad
D. Pulanic
S. Rotz
A. Shreenivas
A. Steinberg
K. Tabbara
A. Tichelli
B. Wirk
J. Yared
G. W. Basak
M. Battiwalla
R. Duarte
B. N. Savani
M. E. D. Flowers
B. E. Shaw
N. Valdes-Sanz
Publicerad i Biology of Blood and Marrow Transplantation
Volym 25
Nummer/häfte 5
Sidor E145-E154
ISSN 1083-8791
Publiceringsår 2019
Publicerad vid Institutionen för neurovetenskap och fysiologi, sektionen för klinisk neurovetenskap
Sidor E145-E154
Språk en
Länkar dx.doi.org/10.1016/j.bbmt.2018.11.0...
Ämnesord Hematopoietic cell, transplantation, Complication, Eye, Review, Prevention, Treatment, nervous-system lymphoma, term-follow-up, cytomegalovirus retinitis, risk-factors, randomized-trial, macular edema, retinal, microvasculopathy, intraocular-pressure, adenovirus infection, toxoplasma-gondii, Hematology, Immunology, Transplantation
Ämneskategorier Neurovetenskaper, Hematologi

Sammanfattning

Non-graft-versus-host disease (GVHD) ocular complications are generally uncommon after hematopoietic cell transplantation (HCT) but can cause prolonged morbidity affecting activities of daily living and quality of life. Here we provide an expert review of non-GVHD ocular complications in a collaboration between transplantation physicians and ophthalmologists through the Late Effects and Quality of Life Working Committee of the Center for International Blood and Marrow Transplant Research and the Transplant Complications Working Party of the European Society of Blood and Marrow Transplantation. Complications discussed in this review include cataracts, glaucoma, ocular infections, ocular involvement with malignancy, ischemic microvascular retinopathy, central retinal vein occlusion, retinal hemorrhage, retinal detachment and ocular toxicities associated with medications. We summarize the incidence, risk factors, screening, prevention, and treatment of individual complications and generate evidence-based recommendations. Baseline ocular evaluation before HCT should be considered in all patients who undergo HCT. Follow-up evaluations should be considered according to clinical signs and symptoms and risk factors. Better preventive strategies and treatments remain to be investigated for individual ocular complications after HCT. Both transplantation physicians and ophthalmologists should be knowledgeable about nonGVHD ocular complications and provide comprehensive collaborative team care. (C) 2018 American Society for Blood and Marrow Transplantation.

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