Till sidans topp

Sidansvarig: Webbredaktion
Sidan uppdaterades: 2012-09-11 15:12

Tipsa en vän
Utskriftsversion

Bipolar disorders: Subtyp… - Göteborgs universitet Till startsida
Webbkarta
Till innehåll Läs mer om hur kakor används på gu.se

Bipolar disorders: Subtypes, treatments, and health inequalities

Doktorsavhandling
Författare Alina (Aikaterini) Karanti
Datum för examination 2020-03-13
ISBN 978-91-7833-731-6
Förlag Göteborgs universitet
Publiceringsår 2020
Publicerad vid Institutionen för neurovetenskap och fysiologi, sektionen för psykiatri och neurokemi
Språk en
Länkar hdl.handle.net/2077/62687
Ämnesord bipolar disorders, drug therapy, lithium, lamotrigine, quetiapine, mood stabilizers, antidepressants, electroconvulsive therapy, psychotherapy, psychoeducation, comorbidity, socioeconomic factors, healthcare disparity, gender, education
Ämneskategorier Psykiatri

Sammanfattning

This thesis comprises five studies based on prospective, longitudinal data from the Swedish national quality register BipoläR. Study I examined the differences between bipolar subtype I and II with respect to clinical features, course of illness, comorbidity, and socioeconomic factors. Study II investigated temporal changes in drug prescription patterns in bipolar disorder. Study III examined the effectiveness of psychoeducation for bipolar disorder. Study IV and V examined health inequalities in the management of bipolar disorder with respect to sex and patients’ educational level, respectively. Results showed noticeable phenomenological differences between the BDI and BDII, where BDII has a different and more complex clinical presentation in terms of illness course and comorbidity (Study I). This supports the validity of separating BDI and BDII. Concerning pharmacological treatment, we found that lithium use decreased during the study period, while lamotrigine and quetiapine increased. The use of antidepressants remained unchanged in BDII but increased somewhat in BDI (Study II). We found that psychoeducation decreased the risk for depressive and manic episodes as well as inpatient care in routine clinical practice (Study III). Lastly, we found differences in the management of bipolar disorder without apparent medical rationale. Whereas women were more likely to receive psychotherapy, antidepressants, benzodiazepines, antipsychotics, lamotrigine, and electroconvulsive therapy, men were more likely to use lithium (Study IV). Further, higher education in patients increased the likelihood of receiving psychotherapy and psychoeducation, but decreased likelihood of receiving first-generation antipsychotics, tricyclic antidepressants, and compulsory inpatient care (Study V).

Sidansvarig: Webbredaktion|Sidan uppdaterades: 2012-09-11
Dela:

På Göteborgs universitet använder vi kakor (cookies) för att webbplatsen ska fungera på ett bra sätt för dig. Genom att surfa vidare godkänner du att vi använder kakor.  Vad är kakor?