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Preferred Reporting Items for RAndomized Trials in Endodontics (PRIRATE) guidelines: a development protocol

Artikel i vetenskaplig tidskrift
Författare V. Nagendrababu
H. F. Duncan
L. Bjorndal
Thomas Kvist
E. Priya
S. J. Pulikkotil
J. Jayaraman
P. M. H. Dummer
Publicerad i International Endodontic Journal
Volym 52
Nummer/häfte 7
Sidor 974-978
ISSN 0143-2885
Publiceringsår 2019
Publicerad vid Institutionen för odontologi, sektion 1
Sidor 974-978
Språk en
Länkar dx.doi.org/10.1111/iej.13087
Ämnesord endodontics, health research reporting guidelines, protocol, randomized clinical trial, evidence-based dentistry, quality assessment, clinical-trials, statement, Dentistry, Oral Surgery & Medicine, hulz kf, 1995, jama-journal of the american medical association, v273, p408
Ämneskategorier Odontologi

Sammanfattning

Randomized clinical trials are acknowledged as the most appropriate methodology for demonstrating the efficacy or effectiveness of one intervention as opposed to another and thus play a major role in clinical decision-making. However, it is recognized that despite the existence of various guidelines, for example, the Consolidated Standards for Reporting Trials (CONSORT) statement, the quality of manuscripts describing randomized trials is often suboptimal. The current project aims to develop and disseminate new guidelines, Preferred Reporting Items for RAndomized Trials in Endodontics (PRIRATE), to improve the planning and reporting quality of randomized trials in the field of Endodontics. The project leads (VN, PD) designed a robust process to develop the PRIRATE guidelines. At first, a steering committee of eight members, including the project leads, was formed. Thereafter, a five-stage consensus process will be followed: initial steps, pre-meeting activities, face-to-face consensus meeting, post-meeting activities and post-publication activities. The steering committee will develop the first draft of the PRIRATE guidelines by identifying relevant and important items from various sources including the CONSORT guidelines and the Clinical and Laboratory Images in Publications (CLIP) principles. This will be followed by the establishment of a PRIRATE Delphi Group (PDG) consisting of 30 members. The individual items of the first draft of the PRIRATE guidelines developed by the steering committee will be evaluated and scored on a 9-point Likert scale by the PDG members. Items with a score of seven and above by more than 70% of PDG members will be included in the second draft of the guidelines, and the Delphi process will be repeated until each item fulfils the set conditions. After obtaining consensus from the PDG, the PRIRATE guidelines will be discussed by 20 selected individuals within a PRIRATE Face-to-face Consensus Meeting Group (PFCMG) to arrive at a final consensus. The final PRIRATE guidelines will be accompanied with an explanation and elaboration document developed by the steering committee and approved by six members, three from the PDG and three from the PFCMG. The PRIRATE guidelines will be published in journals and actively disseminated to educational institutions, national and international academic societies and presented at scientific meetings. The steering committee will periodically revise and update the PRIRATE guidelines based on feedback from stakeholders.

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