Till sidans topp

Sidansvarig: Webbredaktion
Sidan uppdaterades: 2012-09-11 15:12

Tipsa en vän
Utskriftsversion

Moyamoya angiopathy: long… - Göteborgs universitet Till startsida
Webbkarta
Till innehåll Läs mer om hur kakor används på gu.se

Moyamoya angiopathy: long-term follow-up study in a Finnish population

Artikel i vetenskaplig tidskrift
Författare M. Savolainen
S. Mustanoja
J. Pekkola
T. Tyni
A. M. Uusitalo
S. Ruotsalainen
E. Poutiainen
J. Hernesniemi
L. Kivipelto
Turgut Tatlisumak
Publicerad i Journal of Neurology
Volym 266
Nummer/häfte 3
Sidor 574-581
ISSN 0340-5354
Publiceringsår 2019
Publicerad vid Institutionen för neurovetenskap och fysiologi, sektionen för klinisk neurovetenskap
Sidor 574-581
Språk en
Länkar dx.doi.org/10.1007/s00415-018-9154-...
Ämnesord Stroke, Moyamoya angiopathy, Treatment, Prognosis, Follow-up, Quality of life, Mood symptoms, quality-of-life, cognition
Ämneskategorier Neurovetenskaper

Sammanfattning

Background and purposeMoyamoya angiopathy (MMA) is a chronic cerebrovascular disorder predominantly starting in childhood or early adulthood and thus affects the whole lifetime. Little is known on MMAs long-term outcomes in European patients. We report long-term follow-up data on Finnish MMA patients.MethodsWe included patients from our Helsinki University Hospital MMA database and arranged long-term follow-up visits for all the patients. This follow-up included a review of the medical records accumulated in due time, detailed neurological and neuropsychological evaluation, and outcome measures modified Rankin Scale (mRS) and Barthel Index (BI).ResultsThere were 61 MMA patients with a mean follow-up period of 9.5years (SD 6.7years; range 1.3-35.4years; 581 patient-years). Only two patients had died and two-thirds (n=40, 65.6%) had no new events during the follow-up period. Eight patients (13.1%) had an ischemic and five patients (8.2%) a hemorrhagic stroke during the follow-up. There were no differences between operated (n=26) and conservatively (n=35) treated groups regarding recurrent events or the outcome measured with mRS or BI. Finnish MMA patients reported significantly poorer physical and psychological health aspects of QOL when compared to the general Finnish population. Symptoms of low mood were found in 27 (56%) patients.ConclusionsFinnish MMA patients have a benign and stable course with a 3.5% annual stroke risk. We found no differences in the clinical outcomes between the operated and conservative groups, however, the psychosocial well-being requires more attention in MMA patients.

Sidansvarig: Webbredaktion|Sidan uppdaterades: 2012-09-11
Dela:

På Göteborgs universitet använder vi kakor (cookies) för att webbplatsen ska fungera på ett bra sätt för dig. Genom att surfa vidare godkänner du att vi använder kakor.  Vad är kakor?