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Neurodevelopmental problems should be considered in children with febrile seizures.

Artikel i vetenskaplig tidskrift
Författare Gill Nilsson
Joakim Westerlund
Elisabeth Fernell
Eva Billstedt
Carmela Miniscalco
Thomas Arvidsson
Ingrid Olsson
Christopher Gillberg
Publicerad i Acta paediatrica (Oslo, Norway : 1992)
ISSN 1651-2227
Publiceringsår 2019
Publicerad vid Gillbergcentrum
Institutionen för kliniska vetenskaper, Avdelningen för pediatrik
Språk en
Länkar dx.doi.org/10.1111/apa.14716
www.ncbi.nlm.nih.gov/entrez/query.f...
Ämnesord Essence ; Developmental disorder; Febrile seizures; Preschool children
Ämneskategorier Barn- och ungdomspsykiatri

Sammanfattning

Clinical developmental phenotyping of four- to five-year-old children with febrile seizures (FSs).Children with FS (n = 157, corresponding to 3.7% of the targeted general population of four-five-year-olds) had been identified at child healthcare centres in Gothenburg. Parents of 73 children (41 boys, 32 girls) accepted participation in the present study. The assessments included a neuropaediatric assessment, Movement ABC, Wechsler Preschool and Primary Scale of Intelligence-III and parent questionnaires (Five-to-Fifteen (FTF) and Strengths and Difficulties Questionnaire (SDQ)). Hospital records were reviewed, when applicable.One-third of the children had at least one DSM-5 neurodevelopmental disorder diagnosis or marked developmental problems within areas of attention, activity regulation, behaviour, speech and language, general cognition or motor functioning. No differences were found between children with single vs recurrent or simple vs complex FS.Febrile seizure are relatively often associated with Early Symptomatic Syndromes Eliciting Neurodevelopmental Clinical Examinations (ESSENCEs). We found no indications that ESSENCE might be caused by FS per se. However, the results suggest that child healthcare professionals should consider the possibility of ESSENCE in children with a history of FS.

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