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Viewpoint and practical recommendations from a movement disorder specialist panel on objective measurement in the clinical management of Parkinson's disease

Artikel i vetenskaplig tidskrift
Författare P. Odin
K. R. Chaudhuri
J. Volkmann
A. Antonini
A. Storch
E. Dietrichs
Z. Pirtosek
T. Henriksen
M. Horne
D. Devos
Filip Bergquist
Publicerad i Npj Parkinson's Disease
Volym 4
ISSN 2373-8057
Publiceringsår 2018
Publicerad vid Institutionen för neurovetenskap och fysiologi, sektionen för farmakologi
Språk en
Länkar https://doi.org/10.1038/s41531-018-...
Ämnesord quality-of-life, medication adherence, motor fluctuations, care, outcomes, impact, costs, trial, complications, dyskinesias, Neurosciences & Neurology
Ämneskategorier Neurovetenskaper

Sammanfattning

Motor aspects of Parkinson's disease, such as fluctuations and dyskinesia, can be reliably evaluated using a variety of "wearable" technologies, but practical guidance on objective measurement (OM) and the optimum use of these devices is lacking. Therefore, as a first step, a panel of movement disorder specialists met to provide guidance on how OM could be assessed and incorporated into clinical guidelines. A key aspect of the incorporation of OM into the management of Parkinson's disease (PD) is defining cutoff values that separate "controlled" from "uncontrolled" symptoms that can be modified by therapy and that relate to an outcome that is relevant to the person with PD (such as quality of life). Defining cutoffs by consensus, which can be subsequently tested and refined, is the first step to optimizing OM in the management of PD. OM should be used by all clinicians that treat people with PD but the least experienced may find the most value, but this requires guidance from experts to allow non-experts to apply guidelines. While evidence is gained for devices that produce OM, expert opinion is needed to supplement the evidence base.

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