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Trends in mortality risks among 94,328 patients surviving 30 days after a first isolated coronary artery bypass graft procedure from 1987 to 2006: A population-based study

Artikel i vetenskaplig tidskrift
Författare Susanne Nielsen
Lena Björck
Anders Jeppsson
Kok Wai Giang
Kristin Falk
Sylvia Määttä
Tatiana Zverkova Sandström
Annika Rosengren
Publicerad i International Journal of Cardiology
Volym 244
Sidor 316-321
ISSN 0167-5273
Publiceringsår 2017
Publicerad vid Institutionen för vårdvetenskap och hälsa
Institutionen för medicin, avdelningen för molekylär och klinisk medicin
Sidor 316-321
Språk en
Länkar dx.doi.org/10.1016/j.ijcard.2017.05...
Ämnesord Coronary artery bypass graft surgery, Coronary artery disease, Survival, Temporal trends, acute myocardial-infarction, surgery, women, revascularization, outcomes, disease, men, database, sweden, cohort, Cardiovascular System & Cardiology, ahle e, 1994, european heart journal, v15, p1204
Ämneskategorier Klinisk medicin

Sammanfattning

Background: Updated knowledge about survival after coronary artery bypass graft (CABG) surgery is needed. We examined 20-year trends in 4-year survival after a first isolated CABG procedure, compared with that of the general population. Methods: We identified 94,328 patients surviving 30 days after a first isolated CABG 1987-2006 from the Swedish Inpatient Register. Results: Crude annual mortality rates remained stable at approximately 1% in patients aged 18-54 years and at approximately 2% in those aged >= 55 years. After adjustment for comorbidities, 4-year survival in men aged 18-54 and >= 55 years improved by 37% (HR: 0.63, 95% CI, 0.46-0.88) and 31% (HR: 0.69, 95% CI, 0.63-0.76), respectively, (1987-1991 vs. 2002-2006). The corresponding estimate for women aged >= 55 years was 38% (HR: 0.62, 95% CI, 0.52-0.75), with no significant change in survival in women aged b55 years (HR: 1.02, 95% CI, 0.52-2.03). Men and women aged b55 years had higher mortality than the general population, with standardized mortality ratios (SMR) of 1.76 (95% CI, 1.35-2.22) in men and 4.49 (95% CI, 2.74-6.68) in women during the last period (2002-2006). In contrast, patients aged >= 55 years had better survival with a SMR of 0.74 (95% CI, 0.70-0.78) in men and 0.82 (95% CI, 0.74-0.91) in women during 2002-2006. Conclusion: During 1987-2006, there was a significant improvement in survival after CABG for all categories, except in women aged < 55 years. Men and women aged >= 55 years who survived the first 30 days after CABG had a lower mortality risk than the general population.

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