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Retinal Fibre Layer Thickness Measurement in Normal Paediatric Population in Sweden Using Optical Coherence Tomography

Artikel i vetenskaplig tidskrift
Författare Marcelo Ayala
E. Ntoula
Publicerad i Journal of Ophthalmology
Sidor article ID 4160568
ISSN 2090-004X
Publiceringsår 2016
Publicerad vid Institutionen för neurovetenskap och fysiologi
Sidor article ID 4160568
Språk en
Länkar dx.doi.org/10.1155/2016/4160568
Ämneskategorier Oftalmologi

Sammanfattning

Purpose. To evaluate the correlation between peripapillary retinal nerve fibre layer (RNFL) thickness and both age and refraction error in healthy children using optical coherence tomography (OCT). Patients and Methods. 80 healthy children with a mean age of 9.1 years (range 3.8 to 16.7 years) undergoing routine ocular examination at the orthoptic section of the Ophthalmology Department were recruited for this cross-sectional study. After applying cycloplegia, the peripapillary RNFL thickness was measured in both eyes using the Topcon 3D OCT 2000 device. Results. 138 eyes were included in the analysis. The average refractive error (SE) was +1.7 D (range-5.25 to +7.25 D). The mean total RNFL thickness was 105 μm ± 10.3, the mean superior RNFL thickness was 112.7 μm ± 16.5, and the mean inferior RNFL thickness was 132.6 μm ± 18.3. We found no statistically significant effect of age on RNFL thickness (ANOVA, f=0.33, p=0.56). Refraction was proven to have a statistically significant effect (ANOVA, f=67.1, p<0.05) in RNFL measurements. Conclusions. Data obtained from this study may assist in establishing a normative database for a paediatric population. Refraction error should be taken into consideration due to its statistically significant correlation with RNFL thickness. © 2016 Marcelo Ayala and Evangelia Ntoula.

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