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Cognitive disability in alzheimer's disease and its management

Artikel i övriga tidskrifter
Författare M. Corsi
T. Di Raimo
C. Di Lorenzo
Max Rapp-Ricciardi
Trevor Archer
S. Ricci
R. Businaro
Publicerad i Clinica Terapeutica
Volym 167
Nummer/häfte 5
Sidor 123-126
ISSN 0009-9074
Publiceringsår 2016
Publicerad vid Psykologiska institutionen
Sidor 123-126
Språk en
Länkar dx.doi.org/10.7417/ct.2016.1955
Ämnesord Cognitive disability, Alzheimer's disease, intervention strategies, multidomain intervention, medicolegal considerations, musical memory, dementia, impairment, caregivers, interventions, stress, General & Internal Medicine, Pharmacology & Pharmacy
Ämneskategorier Psykologi


Cognitive disability linked to neurodegenerative diseases and in particular to Alzheimer's disease, remains an increasing cause for concern through a dramatic prevalence increment and associated socioeconomic burdens. Initially Alzheimer's disease develops asymptomatically with primary clinical signs, such as memory impairment, decline of spatial and perceptual abilities, occurring at a later stage. This delay implies the possibility of promoting early interventions during the pre-symptomatic stage of the disease. Different strategies have been applied in order to prevent/delay onset of Alzheimer's disease or at least to improve quality of life and health conditions of Alzheimer's disease patients and their caregivers, especially in the absence of current viable therapies. Multidomain interventions, aimed at affecting several risk factors simultaneously, offer a versatility that may attain improved outcomes in comparison with single-domain prevention trials. These multidomain interventions involve diet, physical exercise, cognitive training and social activities, while music therapy, improving self-consciousness and reducing neurofibrils, may contribute to deceleration/delay onset of Alzheimer's disease progression. Information and Communication Technology (ICT) provides broad applications to improve quality of life and well-being of Alzheimer's disease patients and caregivers, suffering from psychological distress, as well as reducing additional public health costs.

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