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Rhythm Control and Its Relation to Symptoms during the First Two Years after Radiofrequency Ablation for Atrial Fibrillation

Artikel i vetenskaplig tidskrift
Författare A. Bjorkenheim
A. Brandes
A. Chemnitz
A. Magnuson
Nils Edvardsson
D. Poci
Publicerad i Pace-Pacing and Clinical Electrophysiology
Volym 39
Nummer/häfte 9
Sidor 914-925
ISSN 0147-8389
Publiceringsår 2016
Publicerad vid Institutionen för medicin
Sidor 914-925
Språk en
Länkar https://gup.ub.gu.se/file/206713
Ämnesord atrial fibrillation, catheter ablation, implantable loop recorder, monitoring, symptoms
Ämneskategorier Kardiologi

Sammanfattning

Clinical Trial RegistrationURL:. Unique Identifier: NCT00697359. ObjectivesTo evaluate rhythm control up to two years after atrial fibrillation (AF) ablation and its relation to reported symptoms. BackgroundThe implantable loop recorder (ILR) continuously records the electrocardiogram (ECG), has an automatic AF detection algorithm, and has a possibility for patients to activate an ECG recording during symptoms. MethodsFifty-seven patients (mean age 57 9 years, 60% male, 88% paroxysmal AF) underwent AF ablation following ILR implantation. Device data were downloaded at the ablation and three, six, 12, 18, and 24 months after ablation. ResultsFifty-four patients completed the two-year follow-up. Thirteen (24%) patients had no AF episodes detected by ILR during follow-up. Ten of 41 patients (24%) with AF recurrence were only detected by ILR and AF recurrences were detected earlier by ILR (P < 0.001). The median AF burden in patients with AF recurrence was 5.7% (interquartile range 0.4-14.4) and was even lower in patients with AF only detected by ILR (P = 0.001). Forty-eight % of the patients indicated symptoms via the patient activator but 33% of those recordings were not due to AF. Early AF recurrence (within 3 months) was highly associated with later AF recurrence (P < 0.001). AF burden >0.5% and longest AF episode >6 hours before the ablation were independent predictors of AF recurrence during intermittent but not continuous monitoring. ConclusionsAfter AF ablation, the AF burden was low throughout the 24 months follow-up. Nevertheless, symptoms were commonly indicated but one-third of patient-activated recordings did not show AF. Continuous monitoring was superior to intermittent follow-up in detecting AF episodes and assessing the AF burden.

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