Till sidans topp

Sidansvarig: Webbredaktion
Sidan uppdaterades: 2012-09-11 15:12

Tipsa en vän
Utskriftsversion

Serum fatty acids in infa… - Göteborgs universitet Till startsida
Webbkarta
Till innehåll Läs mer om hur kakor används på gu.se

Serum fatty acids in infants, reflecting family fish consumption, were inversely associated with allergy development but not related to farm residence.

Artikel i vetenskaplig tidskrift
Författare Karin Jonsson
Malin Barman
Sara Moberg
Agneta Sjöberg
Hilde Kristin Brekke
Bill Hesselmar
Ann-Sofie Sandberg
Agnes E Wold
Publicerad i Acta paediatrica (Oslo, Norway : 1992)
Volym 105
Nummer/häfte 12
Sidor 1462–1471
ISSN 1651-2227
Publiceringsår 2016
Publicerad vid Institutionen för kliniska vetenskaper, Avdelningen för pediatrik
Institutionen för kost- och idrottsvetenskap
Institutionen för biomedicin, avdelningen för infektionssjukdomar
Sidor 1462–1471
Språk en
Länkar dx.doi.org/10.1111/apa.13592
Ämnesord Atopy; eicosapentaenoic acid; farm children; fatty acid composition; serum
Ämneskategorier Lungmedicin och allergi, Pediatrik, Epidemiologi, Näringslära

Sammanfattning

AIM: In this study, differences in serum fatty acid patterns between farm and non-farm infants were investigated and related to subsequent allergy development. We also related allergy-related serum fatty acids to maternal diet and breast milk fatty acids. METHODS: The FARMFLORA birth cohort included 28 farm and 37 non-farm infants. Serum was obtained from 21 farm infants and 29 controls at four months postpartum and analysed for phospholipid fatty acids. Allergy was diagnosed by paediatricians at three years of age. RESULTS: Serum fatty acid patterns were similar in farm and control infants, although farm infants had lower 18:1 omega-7 proportions. Serum proportions of eicosapentaenoic acid (EPA) were unrelated to farming status, but lower in children who subsequently developed allergy, with an odds ratio of 0.47 and 95% confidence interval of 0.27-0.83 (p=0.01) for every 0.1% EPA increase. The infants' serum EPA proportions correlated with breast milk EPA proportions, which, in turn, correlated with maternal oily fish intake during lactation. CONCLUSION: The allergy protective effect of farming was not linked to infant serum fatty acid composition. However, healthy infants had higher proportions of EPA in their sera, probably reflecting a family diet rich in fish, compared to subsequently allergic children.

Sidansvarig: Webbredaktion|Sidan uppdaterades: 2012-09-11
Dela:

På Göteborgs universitet använder vi kakor (cookies) för att webbplatsen ska fungera på ett bra sätt för dig. Genom att surfa vidare godkänner du att vi använder kakor.  Vad är kakor?