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Cognitive Performance Deficits and Dysgraphia in Alzheimer’s Disease Patients

Artikel i vetenskaplig tidskrift
Författare Emanuela Onofri
Marco Mercuri
Maria-Lucia Salesi
Max Rapp-Ricciardi
Trevor Archer
Publicerad i Open Medicine Journal
Volym 2015
Nummer/häfte 2
Sidor 6-16
ISSN 1874-2203
Publiceringsår 2015
Publicerad vid Psykologiska institutionen
Sidor 6-16
Språk en
Länkar dx.doi.org/10.4172/2155-9562.100022...
Ämnesord Key-words: AD, ADL, cognitive tests, correlations, DΔ, deficits, dysgraphia, IADL, MMSE, PQ1.
Ämneskategorier Psykologi, Annan medicin och hälsovetenskap, Hälsovetenskaper

Sammanfattning

Abstract: Introduction: Agraphia or dysgraphia, observed often in early AD, encompasses a progressive disorganization and degeneration of the various components of handwriting. Methods: Deficits in writing ability, dysgraphia, and the relationship with other measures of cognitive decline were studied in a group of 30 patients, originating from the Lazio region, Rome, Italy, presenting a moderate to relatively severe stage of Alzheimer’s disease (AD). Extent of dysgraphia and cognitive performance was compared with a matched group of healthy controls selected from the same region. Results: Several markedly strong relationships between dysgraphia and several measures of cognitive performance in AD patients were observed concomitant with consistent deficits by this patient sample in comparison with the matched group of healthy control subjects were obtained. Additionally, several measures of loss of functional integrity, MMSE, ADL and IADL, were found to be associated with both dysgraphia and impairments in cognitive performance. Conclusion: The present results are discussed from the notion of affected brain regions underlying functions in cognition, language and motor domains that are disturbed in AD.

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