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Portable scintillation detector for lung activity measurements prior to V/PSPECT

Konferensbidrag (offentliggjort, men ej förlagsutgivet)
Författare Malin Larsson
Jakob Himmelman
Johanna Dalmo
Publicerad i Optimization in X-ray and Molecular Imaging, 28-30 May, 2015, Gothenburg, Sweden.
Publiceringsår 2015
Publicerad vid Institutionen för kliniska vetenskaper, Avdelningen för radiofysik
Språk en
Ämnesord Nuclear Medicine V/PSPECT
Ämneskategorier Klinisk medicin

Sammanfattning

Ventilation and perfusion SPECT (V/PSPECT) is a tomographic imaging method using 99mTc labeled carbon particles (technegas) and 99mTc-macro aggregated albumin (MAA), respectively, for examination of the lungs. The primary purpose of V/PSPECT is to diagnose pulmonary embolism (PE). Today in Sahlgrenska University Hospital, the gamma camera is used for determination of enough inhaled technegas before the ventilation SPECT, a sufficient activity in the lungs are 20- 30 MBq. To economize with camera time and eliminate the risk of contamination of the camera detector system it would be advantageous to use a portable detector in a preparation room to ensure an adequate count rate. The aim of this study was to find a method to use a portable scintillation detector for estimation of inhaled techegas in lung tissue before V/PSPECT and to validate the method for clinical use. A scintillation detector (SSL Radhound with SS404 Al probe, Southern Scientific UK, Gamma Data AB, UK), was positioned over and/or laterally of the patient lying on a bed in supine positon. The patient inhaled technegas and the countrate of the portable detector was compared to the total counts from the ventilation SPECT images. The scintillation detector count statistics showed potential to replace the gamma camera measurements of the inhaled lung activity. The detected counts by scintillation detector showed good correlation to the number of counts in the SPECT images. In conclusion, the scintillation measurements can replace the method using a gamma camera for the activity uptake measurement before ventilation SPECT in the clinic.

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