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Exercise Influences in Depressive Disorders: Symptoms, Biomarkers and Telomeres

Artikel i vetenskaplig tidskrift
Författare Trevor Archer
Publicerad i Clinical Depression
Volym 1
Nummer/häfte 1
ISSN 2572-0791
Publiceringsår 2015
Publicerad vid Psykologiska institutionen
Språk en
Länkar doi.org/10.4172/2572-0791.1000e101
Ämnesord Exercise, mood, biomarkers, function, alleviation
Ämneskategorier Psykologi

Sammanfattning

The exact mechanisms concerning how exercise affects the brain, under conditions of health or disorder, are not fully understood and the literature lacks a sufficiency of well-designed studies concerning the effects of exercise training on depressive disorders. Nevertheless, the observed antidepressant actions of exercise are strong enough to warrant its application as a viable alternative to current medications in the treatment of depressive disorders. The beneficial effects of exercise upon cognitive, executive function and working memory, emotional, self-esteem and depressed mood, motivational, anhedonia and psychomotor retardation, and somatic/physical, sleep disturbances and chronic aches and pains, categories of depression are discussed. The ameliorative effects of physical exercise upon several biomarkers associated with depressive states: hypothalamic-pituitary- adrenal (HPA) axis homeostasis, anti-neurodegenerative effects, monoamine metabolism regulation and neuro-immune functioning have been outlined. The notion that physical exercise may function as “scaffolding” that buttresses available network circuits, anti-inflammatory defences and neuroreparative processes, e.g. brain-derived neurotrophic factor (BDNF), holds a certain appeal. In older adults, it has been observed that exercise was associated with significantly lower levels of depressive symptom severity. An activity program based on “nordic walking”, i.e. using staves, was shown to induce a positive effect on depressive symptoms and sleeping disorders in elderly patients, suggesting that Nordic walking based exercise programs should be developed for the elderly who suffer from depression or a sleeping disorder.

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