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Classic Interstitial Cystitis: Unrelated to BPS

Artikel i vetenskaplig tidskrift
Författare Magnus Fall
Ralph Peeker
Publicerad i Current Bladder Dysfunction Reports
Volym 10
Nummer/häfte 1
Sidor 95-102
ISSN 1931-7212
Publiceringsår 2015
Publicerad vid Institutionen för kliniska vetenskaper, Avdelningen för urologi
Sidor 95-102
Språk en
Länkar dx.doi.org/10.1007/s11884-014-0273-...
Ämnesord Bladder pain syndrome, Classification, Interstitial cystitis, Phenotype definitions
Ämneskategorier Urologi och njurmedicin

Sammanfattning

When first recognized, more than one hundred years ago, the term interstitial cystitis (IC) was reserved for subjects with a special type of deep inflammation of the bladder wall. Later, the scope of IC widened, including all kinds of bladder pain syndromes (BPS), giving rise to a lot of confusion and difficulties in research as well as in clinical practice. Herein, recent progress in the understanding of the BPS/IC complex will be discussed, emphasizing the fact that the classic Hunner disease (BPS type 3C according to the European Society for the Study of Interstitial Cystitis (ESSIC) classification) is a well-defined condition that fulfills the requirements of the denomination interstitial cystitis. The paper will also discuss recent research on diagnostics, markers, genetics, and various types of remedies for classic IC. For the benefit of our patients, in BPS/IC, it is time for a final separation of the concepts BPS and IC. Classic IC is a well-defined entity with multiple unique characteristics, those characteristics having a potential for development of a specific rational, pharmacological, and surgical treatment algorithm if further investigated. BPS, on the other hand, seems to include a heterogenic composition of conditions calling for broad attempts to be more closely explored. © 2015, Springer Science+Business Media New York.

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