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Associations Between Oral Health and Risk of Dementia in a 37-Year Follow-Up Study: The Prospective Population Study of Women in Gothenburg

Artikel i vetenskaplig tidskrift
Författare R. Stewart
Ulrika Stenman
Magnus Hakeberg
Catharina Hägglin
Deborah Gustafson
Ingmar Skoog
Publicerad i Journal of the American Geriatrics Society
Volym 63
Nummer/häfte 1
Sidor 100-105
ISSN 0002-8614
Publiceringsår 2015
Publicerad vid Institutionen för odontologi
Institutionen för neurovetenskap och fysiologi, sektionen för psykiatri och neurokemi
Sidor 100-105
Språk en
Länkar dx.doi.org/10.1111/jgs.13194
Ämnesord dementia, tooth loss, oral health, periodontal disease, cohort study, ALZHEIMERS-DISEASE, COGNITIVE IMPAIRMENT, GENERAL DESIGN, DENTAL-HEALTH, EDENTULISM, NUTRITION, MORTALITY, DECLINE, PURPOSE, PEOPLE, Geriatrics & Gerontology, Gerontology
Ämneskategorier Geriatrik

Sammanfattning

ObjectivesTo investigate the association between incident dementia and previous number of teeth measured over a long interval. ParticipantsWomen with (n=158) and without (n=539) dementia in 2000 to 2005. MeasurementsTooth counts in 1968-69, 1980-81, and 1992-93. Covariates included age, education, stroke, myocardial infarction, diabetes mellitus, smoking status, blood pressure, body mass index, and cholesterol level. ResultsAfter adjustment for age, odds ratios (ORs) for dementia in 2000-05, comparing first with fourth tooth count quartiles, were 1.81 (95% confidence interval (CI)=1.03-3.19) for tooth counts measured in 1968, 2.25 (95% CI=1.18-4.32) for those in 1980, and 1.99 (0.92-4.30) for those in 1992. After further adjustment for education, ORs were 1.40 (95% CI=1.03-3.19) for 1968, 1.96 (95% CI=0.98-3.95) for 1980, and 1.59 (95% CI=0.71-3.53) for 1992, and after additional adjustment for vascular risk factors, ORs were 1.38 (95% CI=0.74-2.58) for 1968, 2.09 (95% CI=1.01-4.32) for 1980, and 1.61 (95% CI=0.70-3.68) for 1992. ConclusionIn most of the analyses, lower tooth count was not associated with dementia, although a significant association was found for one of the three examinations. Further research may benefit from more-direct measures of dental and periodontal disease.

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