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Effect of Fluoridated Sealants on Adjacent Tooth Surfaces: A 30-mo Randomized Clinical Trial

Artikel i vetenskaplig tidskrift
Författare M. G. Cagetti
G. Carta
F. Cocco
S. Sale
G. Congiu
A. Mura
L. Strohmenger
Peter Lingström
G. Campus
Publicerad i Journal of Dental Research
Volym 93
Nummer/häfte 7
Sidor 59-65
ISSN 0022-0345
Publiceringsår 2014
Publicerad vid Institutionen för odontologi, sektion 3
Sidor 59-65
Språk en
Länkar dx.doi.org/10.1177/0022034514535808
Ämnesord pit and fissure sealants, fluorides, dental caries, primary teeth, community dentistry, primary, NATIONAL PATHFINDER SURVEY, CHILDRENS ORAL-HEALTH, RESIN-BASED SEALANT, GLASS-IONOMER, INTERPROXIMAL CARIES, PRIMARY DENTITION, FISSURE, SEALANTS, MOLARS, ASSOCIATION, Dentistry, Oral Surgery & Medicine
Ämneskategorier Odontologi

Sammanfattning

A double-blind randomized clinical trial was performed in 6- to 7-yr-old schoolchildren to evaluate, in a 30-mo period, whether the caries increment on the distal surface of the second primary molars adjacent to permanent first molars sealed with fluoride release compounds would be lower with respect to those adjacent to permanent first molars sealed with a nonfluoridated sealant. In sum, 2,776 subjects were enrolled and randomly divided into 3 groups receiving sealants on sound first molars: high-viscosity glass ionomer cement (GIC group); resin-based sealant with fluoride (fluoride-RB group); and a resin-based sealant without fluoride (RB group). Caries (D-1-D-3 level) was recorded on the distal surface of the second primary molar, considered the unit of analysis including only sound surfaces at the baseline. At baseline, no differences in caries prevalence were recorded in the 3 groups regarding the considered surfaces. At follow-up, the prevalence of an affected unit of analysis was statistically lower (p=.03) in the GIC and fluoride-RB groups (p=.04). In the GIC group, fewer new caries were observed in the unit of analysis respect to the other 2 groups. Incidence rate ratios (IRRs) were 0.70 (95% confidence interval: 0.50, 0.68; p < .01) for GIC vs. RB and 0.79 (95% confidence interval: 0.53, 1.04; p = .005) for fluoride-RB vs. RB. Caries incidence was significantly associated with low socioeconomic status (IRR = 1.18; 95% confidence interval: 1.10, 1.42; p = .05). Dental sealant high-viscosity GIC and fluoride-RB demonstrated protection against dental caries, and there was evidence that these materials afforded additional protection for the tooth nearest to the sealed tooth.

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