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Burnout is associated with elevated prolactin levels in men but not in women

Artikel i vetenskaplig tidskrift
Författare Anna-Karin Lennartsson
Håkan Billig
Ingibjörg H Jonsdottir
Publicerad i Journal of Psychosomatic Research
Volym 76
Nummer/häfte 5
Sidor 380-383
ISSN 0022-3999
Publiceringsår 2014
Publicerad vid Institutionen för neurovetenskap och fysiologi
Sidor 380-383
Språk en
Länkar dx.doi.org/10.1016/j.jpsychores.201...
Ämnesord Prolactin, Burnout, Prolonged stress, Men and women, PSYCHOLOGICAL STRESS, JOB STRAIN, SECRETION, CORTISOL, RISK, DEPRESSION, RESPONSES, ESTROGEN, HORMONES, ANXIETY
Ämneskategorier Neurovetenskaper, Fysiologi

Sammanfattning

Objective: Prolactin levels have been shown to be increased by different types of psychosocial stress. Since burnout is a consequence of long-term psychosocial stress, prolactin levels might also be affected in burnout. The aim of this study was to investigate whether there are differences in prolactin levels between individuals who report burnout and others. Method: Morning fasting serum prolactin levels were compared between individuals who reported burnout (24 men and 25 women) and individuals who reported no burnout (25 men and 13 women). Women were tested in the follicular phase of the menstrual cycle. Men and women were analysed separately. Results: Men who reported burnout exhibited significantly higher (34%) serum prolactin levels compared to men who reported no burnout. The prolactin levels in women who reported burnout were not different from the levels in the women who reported no burnout before or after adjusting for estradiol levels. Conclusions: This study indicates that prolactin levels are higher in men with burnout than men without burnout but not affected in women with burnout. Why no association was seen in women needs to be further explored. (C) 2014 Elsevier Inc. All rights reserved.

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