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Quality of life in children and adults with growth hormone deficiency

Kapitel i bok
Författare I. Wiklund
Ann Erling
Kerstin Albertsson-Wikland
Publicerad i In S. Stabler & B. B. Bercu, (Eds.), Therapeutic outcome of endocrine disorders. Efficacy, innovation and quality of life
Sidor 21-29
ISBN 9781461270522
Förlag Springer
Förlagsort New York
Publiceringsår 2000
Publicerad vid Psykologiska institutionen
Institutionen för kvinnors och barns hälsa, Avdelningen för pediatrik
Sidor 21-29
Språk en
Ämneskategorier Annan medicin och hälsovetenskap, Psykologi


There has been a growing recognition among clinicians of the importance of earning more about how patients view the effects of their condition and its treatment. The concept of health-related quality of life represents a method that is commonly used to assess the views of the patients in terms of the physical, social, and emotional aspects of living with their condition (1). Quality of life is an important component of research into outcomes, which is directed toward verifying the extent to which patients are compromised by their current state, and whether they benefit from the health care given. There is growing scientific awareness that clinical indicators are inadequate for explaining health-related quality of life (2). This particularly applies to conditions where there may be few biological markers of disease activity. In fact, in this situation it has been suggested that the ultimate goal of treatment is to maintain or to improve the patients’ quality of life. Outcomes in growth hormone (GH) deficiency include objective measures of height, weight, body composition or bone diameter. In children, intellectual functioning is estimated in addition to the physiological outcomes. These measures, however, do not necessarily reflect the impact of the condition. Neither do changes in these parameters represent valid indicators of health-related quality of life. It is therefore essential to measure quality of life alongside conventional clinical parameters.

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