Till sidans topp

Sidansvarig: Webbredaktion
Sidan uppdaterades: 2012-09-11 15:12

Tipsa en vän
Utskriftsversion

Vertex-based morphometry … - Göteborgs universitet Till startsida
Webbkarta
Till innehåll Läs mer om hur kakor används på gu.se

Vertex-based morphometry in euthymic bipolar disorder implicates striatal regions involved in psychomotor function

Artikel i vetenskaplig tidskrift
Författare B. Liberg
C. J. Ekman
C. Sellgren
A. Johansson
Mikael Landén
Publicerad i Psychiatry Research-Neuroimaging
Volym 221
Nummer/häfte 3
Sidor 173-178
ISSN 0925-4927
Publiceringsår 2014
Publicerad vid Institutionen för neurovetenskap och fysiologi
Sidor 173-178
Språk en
Länkar dx.doi.org/10.1016/j.pscychresns.20...
Ämnesord Magnetic resonance imaging, Bipolar disorder, Basal ganglia, Shape analysis, Volumetry, Psychomotor, MAJOR DEPRESSIVE DISORDER, COGNITIVE IMPAIRMENT, MOTOR RETARDATION, BRAIN, METAANALYSIS, SCHIZOPHRENIA, DYSFUNCTION, VALIDITY, PUTAMEN, UPDATE
Ämneskategorier Psykiatri

Sammanfattning

We hypothesized that psychomotor disturbances in patients with bipolar disorder are associated with morphometric changes in functionally specific regions of the basal ganglia and thalamus. We used structural magnetic resonance imaging and vertex-based morphometry to investigate whether psychomotor performance is associated with changes in volume and shape in euthymic subjects with bipolar disorder (n=27) compared with matched healthy controls (n=27). We saw no significant differences between age- and sex-matched groups in motor performance. We found a statistically significant group difference in the shape of the right putamen in the absence of psychomotor disturbances. There was an association between shape and motor performance in controls that was lacking in patients. We conclude that euthymic subjects with bipolar disorder without psychomotor disturbances show shape changes in regions of the right putamen that contribute to executive functions and motor function. It may be that other brain regions sustain the psychomotor functions that produce nearly identical motor performance in both groups. (C) 2014 Elsevier Ireland Ltd. All rights reserved

Sidansvarig: Webbredaktion|Sidan uppdaterades: 2012-09-11
Dela:

På Göteborgs universitet använder vi kakor (cookies) för att webbplatsen ska fungera på ett bra sätt för dig. Genom att surfa vidare godkänner du att vi använder kakor.  Vad är kakor?