Till sidans topp

Sidansvarig: Webbredaktion
Sidan uppdaterades: 2012-09-11 15:12

Tipsa en vän
Utskriftsversion

Oral and faecal lactobaci… - Göteborgs universitet Till startsida
Webbkarta
Till innehåll Läs mer om hur kakor används på gu.se

Oral and faecal lactobacilli and their expression of mannose-specific adhesins in individuals with and without IgA deficiency.

Artikel i vetenskaplig tidskrift
Författare Elisabeth Lönnermark
Forough Nowrouzian
Ingegerd Adlerberth
Siv Ahrné
Agnes E Wold
Vanda Friman
Publicerad i International journal of medical microbiology : IJMM
Volym 302
Nummer/häfte 1
Sidor 53-60
ISSN 1618-0607
Publiceringsår 2012
Publicerad vid Institutionen för biomedicin, avdelningen för infektionssjukdomar
Sidor 53-60
Språk en
Länkar dx.doi.org/10.1016/j.ijmm.2011.08.0...
Ämneskategorier Mikrobiologi, Bakteriologi, Immunologi inom det medicinska området, Infektionsmedicin

Sammanfattning

Lactobacilli are present in the intestine and oral cavity of most adults. Secretory IgA in mucosal secretions may provide carbohydrate receptors for bacterial adhesins. Here, oral and faecal samples from 33 IgA-deficient individuals and 34 controls were cultured for lactobacilli, which were identified using species-specific PCR or partial 16S rDNA sequencing and tested for expression of mannose-specific adhesins. Lactobacilli were found in the oral cavity of 76% of IgA-deficient and 85% of control individuals. Lactobacillus paracasei and Lactobacillus gasseri dominated in both groups. Lactobacillus fermentum was less common in IgA-deficient individuals than in controls (p=0.0055) and Lactobacillus salivarius was less common in symptomatic than in healthy IgA-deficient individuals (p=0.0051). Faecal samples yielded lactobacilli in most individuals. L. paracasei was most frequent, followed by L. gasseri and Lactobacillus plantarum. Mannose-specific adhesins were expressed more frequently by oral than by faecal isolates (p=0.032) and oral isolates adhered in higher numbers than faecal isolates (46 vs. 14 bacteria/cell, p=0.0038). Faecal isolates from IgA-deficient individuals more frequently expressed mannose-specific adhesins than faecal isolates from controls (p=0.039). Mannose-specific adhesins may be a colonisation factor in the oral cavity, and the presence of secretory IgA may modify adhesin expression. However, secretory IgA seems to have little influence on Lactobacillus species distribution.

Sidansvarig: Webbredaktion|Sidan uppdaterades: 2012-09-11
Dela:

På Göteborgs universitet använder vi kakor (cookies) för att webbplatsen ska fungera på ett bra sätt för dig. Genom att surfa vidare godkänner du att vi använder kakor.  Vad är kakor?