Till sidans topp

Sidansvarig: Webbredaktion
Sidan uppdaterades: 2012-09-11 15:12

Tipsa en vän
Utskriftsversion

Effects of fruit and vege… - Göteborgs universitet Till startsida
Webbkarta
Till innehåll Läs mer om hur kakor används på gu.se

Effects of fruit and vegetable low molecular mass fractions on gene expression in gingival cells challenged with Prevotella intermedia and Actinomyces naeslundii.

Artikel i vetenskaplig tidskrift
Författare Laura Canesi
Cristina Borghi
Monica Stauder
Peter Lingström
Adele Papetti
Jonathan Pratten
Caterina Signoretto
David A Spratt
Mike Wilson
Egija Zaura
Carla Pruzzo
Publicerad i Journal of biomedicine & biotechnology
Volym 2011
Sidor 230630
ISSN 1110-7251
Publiceringsår 2011
Publicerad vid Institutionen för odontologi
Sidor 230630
Språk en
Länkar dx.doi.org/10.1155/2011/230630
Ämnesord Actinomyces, drug effects, Anti-Bacterial Agents, chemistry, pharmacology, Cell Line, Cell Survival, Chicory, chemistry, Fruit, chemistry, Gene Expression, drug effects, Gingiva, cytology, drug effects, microbiology, Humans, Molecular Weight, Plant Extracts, chemistry, pharmacology, Prevotella intermedia, drug effects, Shiitake Mushrooms, chemistry
Ämneskategorier Cariologi

Sammanfattning

Low molecular mass (LMM) fractions obtained from extracts of raspberry, red chicory, and Shiitake mushrooms have been shown to be an useful source of specific antibacterial, antiadhesion/coaggregation, and antibiofilm agent(s) that might be used for protection towards caries and gingivitis. In this paper, the effects of such LMM fractions on human gingival KB cells exposed to the periodontal pathogens Prevotella intermedia and Actinomyces naeslundii were evaluated. Expression of cytokeratin 18 (CK18) and β4 integrin (β4INT) genes, that are involved in cell proliferation/differentiation and adhesion, and of the antimicrobial peptide β2 defensin (HβD2) in KB cells was increased upon exposure to either live or heat-killed bacteria. All LMM fractions tested prevented or reduced the induction of gene expression by P. intermedia and A. naeslundii depending on the experimental conditions. Overall, the results suggested that LMM fractions could modulate the effects of bacteria associated with periodontal disease in gingival cells.

Sidansvarig: Webbredaktion|Sidan uppdaterades: 2012-09-11
Dela:

På Göteborgs universitet använder vi kakor (cookies) för att webbplatsen ska fungera på ett bra sätt för dig. Genom att surfa vidare godkänner du att vi använder kakor.  Vad är kakor?