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Post-Term Birth is Associated with Greater Risk of Obesity in Adolescent Males.

Artikel i vetenskaplig tidskrift
Författare Jacques Beltrand
Tanya K Soboleva
Paul R Shorten
José G B Derraik
Paul Hofman
Kerstin Albertsson-Wikland
Ze'ev Hochberg
Wayne S Cutfield
Publicerad i The Journal of pediatrics
Volym 160
Nummer/häfte 5
Sidor 769–773
ISSN 1097-6833
Publiceringsår 2012
Publicerad vid Institutionen för kliniska vetenskaper, Avdelningen för pediatrik
Sidor 769–773
Språk en
Länkar dx.doi.org/10.1016/j.jpeds.2011.10....
Ämneskategorier Pediatrik

Sammanfattning

OBJECTIVE: To test the hypothesise that post-term birth (>42 weeks gestation) adversely affects longitudinal growth and weight gain throughout childhood. STUDY DESIGN: A total of 525 children (including 17 boys and 20 girls born post-term) were followed from birth to age 16 years. Weight and height were recorded prospectively throughout childhood, and respective velocities from birth to end of puberty were calculated using a mathematical model. RESULTS: At birth, post-term girls were slimmer than term girls (ponderal index, 27.7±2.6 kg/m(3) vs 26.3±2.8 kg/m(3); P<.05). At age 16 years, post-term boys were 11.8 kg heavier than term subjects (body mass index [BMI], 25.4±5.5 kg/m(2) vs 21.7±3.1 kg/m(2); P<.01). The rate of obesity was 29% in post-term boys and 7% in term boys (P<.01), and the combined rate of overweight and obesity was 47% in post-term boys and 13% in term boys (P<.01). Weight velocity, but not height velocity, was higher in post-term boys at age 1.5-7 years (P<.05) and again at age 11.5-16 years (P<.05). BMI was higher in post-term boys at age 3 years, with the difference increasing thereafter. BMI and growth were similar in post-term and term girls. CONCLUSION: In this post-term birth cohort, boys, but not girls, demonstrated accelerated weight gain during childhood, leading to greater risk of obesity in adolescence.

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