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Classification models for early identification of persons at risk for dementia in primary care: an evaluation in a sample aged 80 years and older.

Artikel i vetenskaplig tidskrift
Författare Tessa N van den Kommer
Daniel E Bontempo
Hannie C Comijs
Scott M Hofer
Miranda G Dik
Andrea M Piccinin
Cees Jonker
Dorly J H Deeg
Boo Johansson
Publicerad i Dementia and geriatric cognitive disorders
Volym 28
Nummer/häfte 6
Sidor 567-577
ISSN 1421-9824
Publiceringsår 2009
Publicerad vid Psykologiska institutionen
Sidor 567-577
Språk en
Länkar dx.doi.org/10.1159/000261501
Ämnesord Aged, 80 and over, psychology, Alcohol Drinking, epidemiology, Biological Markers, Cost-Benefit Analysis, Data Interpretation, Statistical, Dementia, classification, diagnosis, economics, Depression, psychology, Diabetes Mellitus, psychology, Female, Humans, Longitudinal Studies, Male, Memory Disorders, diagnosis, psychology, Models, Statistical, Neuropsychological Tests, Primary Health Care, Prognosis, Psychiatric Status Rating Scales, Risk Assessment, classification, methods, statistics & numerical data, Smoking, psychology, Sweden, epidemiology, Twin Studies as Topic
Ämneskategorier Psykologi

Sammanfattning

AIM: To evaluate previously developed classification models to make implementation in primary care possible and aid early identification of persons at risk for dementia. METHODS: Data were drawn from the OCTO-Twin study. At baseline, 521 persons >or= 80 years of age were nondemented, and for 387 a blood sample was available. Predictors of dementia were collected and analyzed in initially nondemented persons using generalized estimating equations and Cox survival analyses. RESULTS: In the basic model using predictors already known or easily obtained (basic set), the mean 2-year predictive value increased from 6.9 to 28.8% in persons with memory complaints and an MMSE score

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