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Evaluation of screening procedures for congenital cataracts.

Artikel i vetenskaplig tidskrift
Författare Gunilla Magnusson
P Jakobsson
U Kugelberg
A Lundvall
E Maly
K Tornqvist
Maths Abrahamsson
B Andreasson
Magnus P. Borres
U Broberger
Lena Hellström-Westas
R Kornfält
N Nelson
Johan Sjöstrand
Klara Thiringer
Publicerad i Acta paediatrica (Oslo, Norway : 1992)
Volym 92
Nummer/häfte 12
Sidor 1468-73
ISSN 0803-5253
Publiceringsår 2003
Publicerad vid Institutionen för klinisk neurovetenskap, Sektionen för oftalmologi
Institutionen för kvinnors och barns hälsa, Avdelningen för pediatrik
Sidor 1468-73
Språk en
Länkar www.ncbi.nlm.nih.gov/entrez/query.f...
Ämnesord Cataract, congenital, diagnosis, Humans, Infant, Infant, Newborn, Neonatal Screening, methods, Retrospective Studies
Ämneskategorier Oftalmologi, Folkhälsomedicinska forskningsområden, Barn

Sammanfattning

AIM: To evaluate the efficacy of two different Swedish screening procedures for early detection of congenital cataracts in comparison with no screening. METHODS: Children born between January 1992 and December 1998 in Swedish regions with an established eye-screening routine procedure, diagnosed with congenital cataract, and operated on before 1 y of age, were included in a retrospective study. Age at referral and age at time of the operation were compared between regions using different screening procedures: screening in the maternity wards (Region 1), at the well-baby clinics (Region 2) and one region without any screening (Region 3). RESULTS: Seventy-two children were included in the study. Concerning early diagnosis and surgery, Region 1 differed significantly from Regions 2 and 3, which were more similar and were combined for further analysis. The difference in detected cases was greatest at 21 d of age (55% vs 18%; p < 0.001), but persisted even at 100 d of age (78% vs 64%; p < 0.02). Region 1 screening resulted in more and earlier cases detected than the other two regions (22 vs 15 per 100,000 births). In 72% of all cases, surgery was performed in response to referrals from either the maternity wards (36%), or the well-baby clinics (36%). However, half of the cases from the well-baby clinics were detected too late, i.e. at > 100 d. CONCLUSION: Eye screening in the maternity ward is preferable to well-baby clinic screening and to no screening at all, since it leads to early detection. Screening should also be performed routinely at well-baby clinics within the period when successful treatment is possible.

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