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Assessment of health-related quality of life and patient satisfaction in children and adolescents with growth hormone deficiency or idiopathic short stature - part 1: a critical evaluation of available tools

Artikel i vetenskaplig tidskrift
Författare A. L. Brutt
D. E. Sandberg
John Chaplin
H. Wollmann
M. Noeker
M. Koltowska-Häggstrom
M. Bullinger
Publicerad i Hormone Research
Volym 72
Nummer/häfte 2
Sidor 65-73
ISSN 1423-0046
Publiceringsår 2009
Publicerad vid Institutionen för kliniska vetenskaper
Sidor 65-73
Språk en
Länkar dx.doi.org/10.1159/000232158
Ämneskategorier Medicin och Hälsovetenskap

Sammanfattning

The concept of health-related quality of life (HrQoL) reflects the subjective perception of health and includes aspects of well-being and functioning in physical, emotional, mental and social life domains. Nowadays, HrQoL has become a relevant treatment outcome from epidemiological and clinical perspectives and is also broadly employed in health economic analyses. To assess HrQoL generic as well as condition-specific instruments are used. The former are applicable to a wide range of health conditions and aim at measuring HrQoL across different conditions. The latter focus on capturing the impact of a specific disease. Although HrQoL research in adults is now well-advanced, there are still open questions regarding how to assess HrQoL in pediatric conditions, such as short stature. Eight generic (one chronic-generic) and seven condition-specific (one treatment-specific) instruments used in HrQoL research in short stature of youth are described. Additionally, this mini review identifies a need for further research and indicates potential directions.

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