Till sidans topp

Sidansvarig: Webbredaktion
Sidan uppdaterades: 2012-09-11 15:12

Tipsa en vän
Utskriftsversion

Puncture of a lumbar inte… - Göteborgs universitet Till startsida
Webbkarta
Till innehåll Läs mer om hur kakor används på gu.se

Kontaktformulär








 


OBS! Vill du ha svar, ange e-post eller telefonnummer!




Puncture of a lumbar intervertebral disc induces changes in spontaneous pain behavior: an experimental study in rats

Artikel i vetenskaplig tidskrift
Författare Kjell Olmarker
Publicerad i Spine
Volym 33
Nummer/häfte 8
Sidor 850-5
ISSN 1528-1159 (Electronic)
Publiceringsår 2008
Publicerad vid Institutionen för kliniska vetenskaper
Sidor 850-5
Språk en
Länkar www.ncbi.nlm.nih.gov/entrez/query.f...
Ämnesord Animals, Behavior, Animal/*physiology, Disease Models, Animal, Grooming/physiology, Hypokinesia/physiopathology/psychology, Intervertebral Disk/*injuries/physiopathology, Intervertebral Disk Displacement/etiology/physiopathology/*psychology, Lumbar Vertebrae/injuries/pathology, Motor Activity/physiology, Pain/physiopathology/*psychology, Punctures, Rats, Wounds, Penetrating/complications/physiopathology/*psychology
Ämneskategorier Ortopedi

Sammanfattning

STUDY DESIGN: Changes in spontaneous behavior was studied in rats after a controlled puncture of a lumbar intervertebral disc. OBJECTIVE: To study if puncture of a lumbar disc would induce recordable changes in spontaneous pain behavior. SUMMARY OF BACKGROUND DATA: Anular tears are common and may be found both in patients with low back pain and in asymptomatic patients. It has been suggested that anular injury may relate to low back pain either by stimulation of local sensory receptors in the posterior part of the anulus fibrosus or by ingrowth of newly formed nerve fibers into the deeper parts of the disc. The objective of the study was to analyze if a controlled puncture of a lumbar intervertebral disc might induce recordable changes in spontaneous behavior of rats. METHODS: After anesthesia, the L4-L5 disc was punctured in 10 rats. Ten other rats received sham surgery. Spontaneous behavior was assessed at days 1, 3, 7, 14, and 21 after surgery. RESULTS: Statistically significant differences in behavior were seen at all days analyzed. Most consistent were increases in "grooming" and in "wet-dog shakes." CONCLUSION: Puncture of a lumbar intervertebral disc in the rat produces changes in spontaneous behavior mainly seen as increased "grooming" and "wet-dog shakes," 2 behaviors that have been suggested to indicate stress and pain.

Sidansvarig: Webbredaktion|Sidan uppdaterades: 2012-09-11
Dela:

På Göteborgs universitet använder vi kakor (cookies) för att webbplatsen ska fungera på ett bra sätt för dig. Genom att surfa vidare godkänner du att vi använder kakor.  Vad är kakor?

Denna text är utskriven från följande webbsida:
http://www.gu.se/forskning/publikation/?tipFriend=true&tipUrl=http%3A%2F%2Fwww.gu.se%2Fforskning%2Fpublikation%2F%3FfeedbackForm%3Dtrue%26returnAddress%3Dhttp%253A%252F%252Fwww.gu.se%252Fforskning%252Fpublikation%252F%253Fprint%253Dtrue%2526publicationId%253D82005%26recipientName%3DWebbredaktion%26encodedEmail%3DYWxsYW4uZXJpa3Nzb25AZ3Uuc2U%26print%3Dtrue%26publicationId%3D82005&feedbackForm=true&encodedEmail=YWxsYW4uZXJpa3Nzb25AZ3Uuc2U&publicationId=82005
Utskriftsdatum: 2020-07-12