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Clinical and imaging observations of desmoid tumors left without treatment

Artikel i vetenskaplig tidskrift
Författare Mikael Dalén
Mats Geijer
Henry Kvist
Peter Bergh
Björn Gunterberg
Publicerad i Acta Orthopaedica
Volym 77
Nummer/häfte 6
Sidor 932-7
ISSN 1745-3674 (Print)
Publiceringsår 2006
Publicerad vid Institutionen för kliniska vetenskaper
Sidor 932-7
Språk en
Länkar www.ncbi.nlm.nih.gov/pubmed/1726020...
Ämnesord Adolescent, Adult, Aged, Child, Diagnostic Imaging, Female, Fibromatosis, Abdominal/*diagnosis, Fibromatosis, Aggressive/*diagnosis, Follow-Up Studies, Humans, Male, Middle Aged, *Neoplasm Regression, Spontaneous, Retrospective Studies, Soft Tissue Neoplasms/*diagnosis
Ämneskategorier Medicin och Hälsovetenskap, Tumörbiologi, Ortopedi

Sammanfattning

BACKGROUND: Until now, surgical treatment has been the mainstay in the treatment of desmoid tumors, even though it is associated with a high recurrence rate. There have, however, been occasional case reports showing that desmoid tumors may spontaneously decrease in size or even disappear. PATIENTS AND METHODS: This is a retrospective review of 8 patients with abdominal (5) or extra-abdominal (3) desmoid tumors who were followed both clinically and with imaging techniques (sonography, CT or MRI). Mean follow-up time was 4.4 (0.8-7.5) years. Tumor volume was assessed in each investigation and followed over time. RESULTS: 3 tumors disappeared, 2 diminished in size, 1 did not change and 2 tumors became larger, 1 of which had tripled in volume at the latest follow-up. INTERPRETATION: Desmoid tumors have probably been overtreated in the past. Many of them tend to regress spontaneously.

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