Till sidans topp

Sidansvarig: Webbredaktion
Sidan uppdaterades: 2012-09-11 15:12

Tipsa en vän
Utskriftsversion

Prevalence of Klinefelter… - Göteborgs universitet Till startsida
Webbkarta
Till innehåll Läs mer om hur kakor används på gu.se

Prevalence of Klinefelter's syndrome in male breast cancer patients

Artikel i vetenskaplig tidskrift
Författare Ragnar Hultborn
C. Hanson
Istvan Köpf
I. Verbiene
Elisabet Warnhammar Finnborg
Anna Weimarck
Publicerad i Anticancer Res
Volym 17
Nummer/häfte 6D
Sidor 4293-7
ISSN 0250-7005 (Print)
Publiceringsår 1997
Publicerad vid Institutionen för särskilda specialiteter, Avdelningen för onkologi
Sidor 4293-7
Språk en
Länkar www.ncbi.nlm.nih.gov/entrez/query.f...
Ämnesord Aged, Breast Neoplasms, Male/complications/*epidemiology/pathology/surgery, Humans, In Situ Hybridization, Fluorescence, Klinefelter Syndrome/complications/*epidemiology/pathology, Lymphatic Metastasis, Male, Neoplasm Metastasis, Prevalence, Probability, Registries, Survival Rate, Sweden/epidemiology
Ämneskategorier Cancer och onkologi

Sammanfattning

Klinefelter's syndrome (KS, XXY) as a risk factor for developing breast cancer was evaluated in a retrospective study of 93 unselected male breast cancer patients from the Healthcare region of Western Sweden. Archival normal material from lymph nodes or skin and subcutaneous tissue was examined using the FISH (fluorescence in situ hybridisation)-technique. The best yield of intact nuclei was obtained from lymph node tissue. The prevalence rate of KS in males with breast cancer was found to be 7.5 per cent, a much higher rate than previously reported (approximately 3 per cent). Methodological differences are suggested to cause the increased prevalence rate. Based on our finding and on the prevalence of KS in the normal population as well as on the incidence of MBC, a 50-fold increased risk of developing breast cancer in males with KS relative to normal males was found. The same median age at diagnosis, 72 years, was established for both groups of patients. No differences in survival were seen.

Sidansvarig: Webbredaktion|Sidan uppdaterades: 2012-09-11
Dela:

På Göteborgs universitet använder vi kakor (cookies) för att webbplatsen ska fungera på ett bra sätt för dig. Genom att surfa vidare godkänner du att vi använder kakor.  Vad är kakor?