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Secular trends of birthweight in boys from 1950 to 2010

Artikel i vetenskaplig tidskrift
Författare Jimmy Célind
M. Hedlund
Maria Bygdell
Arvid Sondén
Anders Elfvin
Jenny Kindblom
Publicerad i Pediatrics and Neonatology
ISSN 1875-9572
Publiceringsår 2019
Publicerad vid Core Facilities, Bioinformatics
Centre for Bone and Arthritis Research
Institutionen för kliniska vetenskaper, Avdelningen för pediatrik
Språk en
Länkar dx.doi.org/10.1016/j.pedneo.2019.01...
Ämnesord birthweight, epidemiology, fetal growth, secular trends, article, birth weight, body mass, child, cohort analysis, controlled study, fetus growth, human, linear regression analysis, major clinical study, male, school health service, Swedish citizen
Ämneskategorier Pediatrik

Sammanfattning

Background: Birthweight is an indicator of fetal development and intrauterine conditions and is associated with future health outcomes. Secular birthweight trends prior to the 1970s are mostly unknown. Our aim was to explore secular birthweight trends in Swedish boys from 1950 to 2010. Methods: We have collected detailed growth data including birthweight from archived School Health Care records for children born in Gothenburg from 1946 and onwards and established a unique population-based cohort, the Body Mass Index Epidemiology Study (BEST). The birthweight cohort spans six decades (1950–2010) and includes 46,548 boys. Results: The mean birthweight of the complete study cohort was 3580 ± 562 g. Linear regression analysis of the entire period revealed a minimal negative secular trend for birthweight (BETA = −0.4 g/year; p < 0.01). However, three distinct trends appeared during sub-periods: a decrease 1950–80, an increase 1980–2000 and another decrease 2000–2010. Conclusion: We demonstrate that birthweight in boys has undergone periodic decreases and subsequent increases, but the overall trend from the 1950s to the present is stable. © 2019

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