Till sidans topp

Sidansvarig: Webbredaktion
Sidan uppdaterades: 2012-09-11 15:12

Tipsa en vän
Utskriftsversion

Guided bone regeneration:… - Göteborgs universitet Till startsida
Webbkarta
Till innehåll Läs mer om hur kakor används på gu.se

Guided bone regeneration: materials and biological mechanisms revisited

Forskningsöversiktsartikel
Författare Ibrahim Elgali
Omar Omar
Christer Dahlin
Peter Thomsen
Publicerad i European Journal of Oral Sciences
Volym 125
Nummer/häfte 5
Sidor 315-337
ISSN 0909-8836
Publiceringsår 2017
Publicerad vid Institutionen för kliniska vetenskaper, Avdelningen för biomaterialvetenskap
Sidor 315-337
Språk en
Länkar doi.org/10.1111/eos.12364
Ämnesord biocompatible materials, growth factors, guided bone regeneration, membrane, osseointegration, alveolar ridge augmentation, platelet-rich fibrin, anorganic bovine, bone, resorbable polymeric membranes, controlled clinical-trial, calcium-sulfate barrier, randomized controlled-trial, asymmetric porous, structure, occlusive titanium barrier, beta-tricalcium phosphate
Ämneskategorier Odontologi, Biomaterialvetenskap

Sammanfattning

Guided bone regeneration (GBR) is commonly used in combination with the installment of titanium implants. The application of a membrane to exclude non-osteogenic tissues from interfering with bone regeneration is a key principle of GBR. Membrane materials possess a number of properties which are amenable to modification. A large number of membranes have been introduced for experimental and clinical verification. This prompts the need for an update on membrane properties and the biological outcomes, as well as a critical assessment of the biological mechanisms governing bone regeneration in defects covered by membranes. The relevant literature for this narrative review was assessed after a MEDLINE/PubMed database search. Experimental data suggest that different modifications of the physicochemical and mechanical properties of membranes may promote bone regeneration. Nevertheless, the precise role of membrane porosities for the barrier function of GBR membranes still awaits elucidation. Novel experimental findings also suggest an active role of the membrane compartment per se in promoting the regenerative processes in the underlying defect during GBR, instead of being purely a passive barrier. The optimization of membrane materials by systematically addressing both the barrier and the bioactive properties is an important strategy in this field of research.

Sidansvarig: Webbredaktion|Sidan uppdaterades: 2012-09-11
Dela:

På Göteborgs universitet använder vi kakor (cookies) för att webbplatsen ska fungera på ett bra sätt för dig. Genom att surfa vidare godkänner du att vi använder kakor.  Vad är kakor?